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Article / Publication Details AbstractIntroduction: Intravitreal injections are currently the most common intraocular surgical procedure worldwide. Some studies have reported a higher risk of intraoperative complications, namely posterior capsular rupture (PCR), during cataract surgery. The aim of this retrospective and observational study, conducted at Department of Ophthalmology, Centro Hospitalar Universitário do Porto, was to assess the risk of posterior capsular rupture (PCR) during cataract surgery in eyes previously treated with intravitreal injections (IVI) with antivascular endothelial growth factor (anti-VEGF) and/or corticosteroids. Methods: Eyes undergoing cataract surgery between June 2019 and May 2021. Combined surgeries, such as glaucoma surgery and pars plana vitrectomy (PPV) were excluded. The occurrence of PCR during cataract surgery in treated and previously untreated eyes with IVI was analyzed. Results: A total of 5813 cataract surgeries were analyzed; 4.1% of the cases had previously undergone IVI. The PCR rate in cataract surgery was 1.8%: 6.7% in eyes previously treated with IVI and 1.6% without previous IVI (OR=4.5, 95% CI: 2.6-7.7, p
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