A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions

Parenti I, Rabaneda LG, Schoen H, Novarino G. Neurodevelopmental disorders: from genetics to functional pathways. Trends Neurosci. 2020;43(8):608–21 (Epub 2020/06/09).

Article  CAS  PubMed  Google Scholar 

Lenartowicz A, Loo SK. Use of EEG to diagnose ADHD. Curr Psychiatry Rep. 2014;16(11):498 (Epub 2014/09/23).

Article  PubMed  PubMed Central  Google Scholar 

Masi A, DeMayo MM, Glozier N, Guastella AJ. An overview of autism spectrum disorder, heterogeneity and treatment options. Neurosci Bull. 2017;33(2):183–93 (Epub 2017/02/19).

Article  PubMed  PubMed Central  Google Scholar 

Bishop DVM. What causes specific language impairment in children? Curr Dir Psychol Sci. 2006;15(5):217–21 (Epub 2008/11/15).

Article  PubMed  PubMed Central  Google Scholar 

Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry. 2003;160(4):636–45 (Epub 2003/04/02).

Article  PubMed  Google Scholar 

Almasy L, Blangero J. Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design. Am J Med Genet. 2001;105(1):42–4 (Epub 2001/06/27).

Article  CAS  PubMed  Google Scholar 

Blokland GAM, Mesholam-Gately RI, Toulopoulou T, Del Re EC, Lam M, DeLisi LE, et al. Heritability of neuropsychological measures in schizophrenia and nonpsychiatric populations: a systematic review and meta-analysis. Schizophr Bull. 2017;43(4):788–800 (Epub 2016/11/23).

Article  PubMed  Google Scholar 

Plomin R, von Stumm S. The new genetics of intelligence. Nat Rev Genet. 2018;19(3):148–59 (Epub 2018/01/18).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Visscher PM, Hill WG, Wray NR. Heritability in the genomics era—concepts and misconceptions. Nat Rev Genet. 2008;9(4):255–66 (Epub 2008/03/06).

Article  CAS  PubMed  Google Scholar 

van Soelen IL, Brouwer RM, van Leeuwen M, Kahn RS, Hulshoff Pol HE, Boomsma DI. Heritability of verbal and performance intelligence in a pediatric longitudinal sample. Twin Res Hum Genet. 2011;14(2):119–28 (Epub 2011/03/24).

Article  PubMed  Google Scholar 

Ronald A, Viding E, Happe F, Plomin R. Individual differences in theory of mind ability in middle childhood and links with verbal ability and autistic traits: a twin study. Soc Neurosci. 2006;1(3–4):412–25 (Epub 2008/07/18).

Article  PubMed  Google Scholar 

Constantino JN, Todd RD. Autistic traits in the general population: a twin study. Arch Gen Psychiatry. 2003;60(5):524–30 (Epub 2003/05/14).

Article  PubMed  Google Scholar 

Lowe JK, Werling DM, Constantino JN, Cantor RM, Geschwind DH. Social responsiveness, an autism endophenotype: genomewide significant linkage to two regions on chromosome 8. Am J Psychiatry. 2015;172(3):266–75 (Epub 2015/03/03).

Article  PubMed  Google Scholar 

Pineda DA, Lopera F, Puerta IC, Trujillo-Orrego N, Aguirre-Acevedo DC, Hincapie-Henao L, et al. Potential cognitive endophenotypes in multigenerational families: segregating ADHD from a genetic isolate. Atten Deficit Hyp Disord. 2011;3(3):291–9 (Epub 2011/07/23).

Article  Google Scholar 

Missitzi J, Gentner R, Misitzi A, Geladas N, Politis P, Klissouras V, et al. Heritability of motor control and motor learning. Physiol Rep. 2013;1(7):e00188 (Epub 2014/04/20).

Article  PubMed  PubMed Central  Google Scholar 

Williams LR, Gross JB. Heritability of motor skill. Acta Genet Med Gemellol. 1980;29(2):127–36 (Epub 1980/01/01).

Article  CAS  PubMed  Google Scholar 

Burton BK, Hjorthoj C, Jepsen JR, Thorup A, Nordentoft M, Plessen KJ. Research review: do motor deficits during development represent an endophenotype for schizophrenia? A meta-analysis. J Child Psychol Psychiatry. 2016;57(4):446–56 (Epub 2015/11/19).

Article  PubMed  Google Scholar 

Iacono WG, Vaidyanathan U, Vrieze SI, Malone SM. Knowns and unknowns for psychophysiological endophenotypes: integration and response to commentaries. Psychophysiology. 2014;51(12):1339–47 (Epub 2014/11/13).

Article  PubMed  PubMed Central  Google Scholar 

Constantino JN, Kennon-McGill S, Weichselbaum C, Marrus N, Haider A, Glowinski AL, et al. Infant viewing of social scenes is under genetic control and is atypical in autism. Nature. 2017;547(7663):340–4 (Epub 2017/07/13).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moon AL, Haan N, Wilkinson LS, Thomas KL, Hall J. CACNA1C: association with psychiatric disorders, behavior, and neurogenesis. Schizophr Bull. 2018;44(5):958–65 (Epub 2018/07/10).

Article  PubMed  PubMed Central  Google Scholar 

Dedic N, Pohlmann ML, Richter JS, Mehta D, Czamara D, Metzger MW, et al. Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. Mol Psychiatry. 2018;23(3):533–43 (Epub 2017/07/12).

Article  CAS  PubMed  Google Scholar 

Eichler EE, Flint J, Gibson G, Kong A, Leal SM, Moore JH, et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet. 2010;11(6):446–50 (Epub 2010/05/19).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, et al. Finding the missing heritability of complex diseases. Nature. 2009;461(7265):747–53 (Epub 2009/10/09).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kong A, Steinthorsdottir V, Masson G, Thorleifsson G, Sulem P, Besenbacher S, et al. Parental origin of sequence variants associated with complex diseases. Nature. 2009;462(7275):868–74 (Epub 2009/12/18).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Benonisdottir S, Oddsson A, Helgason A, Kristjansson RP, Sveinbjornsson G, Oskarsdottir A, et al. Epigenetic and genetic components of height regulation. Nat Commun. 2016;7:13490 (Epub 2016/11/17).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mozaffari SV, DeCara JM, Shah SJ, Sidore C, Fiorillo E, Cucca F, et al. Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree. Communications biology. 2019;2:28 (Epub 2019/01/25).

Article  PubMed  PubMed Central  Google Scholar 

Lawson HA, Cheverud JM, Wolf JB. Genomic imprinting and parent-of-origin effects on complex traits. Nat Rev Genet. 2013;14(9):609–17 (Epub 2013/08/07).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Weaver JR, Bartolomei MS. Chromatin regulators of genomic imprinting. Biochem Biophys Acta. 2014;1839(3):169–77 (Epub 2013/12/19).

CAS  PubMed  Google Scholar 

Pearson CE. Slipping while sleeping? Trinucleotide repeat expansions in germ cells. Trends Mol Med. 2003;9(11):490–5 (Epub 2003/11/08).

Article  CAS  PubMed  Google Scholar 

Cassidy SB, Dykens E, Williams CA. Prader-Willi and Angelman syndromes: sister imprinted disorders. Am J Med Genet. 2000;97(2):136–46 (Epub 2001/02/17).

Article  CAS  PubMed  Google Scholar 

Buiting K. Prader-Willi syndrome and Angelman syndrome. Am J Med Genet C Semin Med Genet. 2010;154C(3):365–76 (Epub 2010/08/31).

Article  CAS  PubMed  Google Scholar 

Chamberlain SJ, Lalande M. Neurodevelopmental disorders involving genomic imprinting at human chromosome 15q11–q13. Neurobiol Dis. 2010;39(1):13–20 (Epub 2010/03/23).

Article  CAS  PubMed  Google Scholar 

Nudel R, Simpson NH, Baird G, O’Hare A, Conti-Ramsden G, Bolton PF, et al. Associations of HLA alleles with specific language impairment. J Neurodevelop Disord. 2014;6(1):1 (Epub 2014/01/18).

Article  Google Scholar 

Nudel R, Simpson NH, Baird G, O’Hare A, Conti-Ramsden G, Bolton PF, et al. Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment. Genes Brain Behav. 2014;13(4):418–29 (Epub 2014/02/28).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pettigrew KA, Frinton E, Nudel R, Chan MTM, Thompson P, Hayiou-Thomas ME, et al. Further evidence for a parent-of-origin effect at the NOP9 locus on language-related phenotypes. J Neurodev Disord. 2016;8:24 (Epub 2016/06/17).

Article  PubMed  PubMed Central  Google Scholar 

Connolly S, Anney R, Gallagher L, Heron EA. A genome-wide investigation into parent-of-origin effects in autism spectrum disorder identifies previously associated genes including SHANK3. Eur J Hum Genet. 2017;25(2):234–9 (Epub 2016/11/24).

Article  CAS  PubMed  Google Scholar 

Mott R, Yuan W, Kaisaki P, Gan X, Cleak J, Edwards A, et al. The architecture of parent-of-origin effects in mice. Cell. 2014;156(1–2):332–42 (Epub 2014/01/21).

留言 (0)

沒有登入
gif