* Corresponding Author; email: [email protected]

1Molecular Carcinogenesis Group, Department of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece

3Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom

5Faculty Institute for Cancer Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom

6Biomedical Research Foundation, Academy of Athens, Athens, Greece

7Center for New Biotechnologies and Precision Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece

8Faculty of Health and Medical Sciences, University of Surrey, United Kingdom