Long term results after intraocular surgery in treated retinoblastoma eyes

Ocular Oncology and Pathology

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Article / Publication Details Abstract

Introduction: To analyze the results of intraocular surgery in treated retinoblastoma eyes and to assess the long-term results with a priority on local recurrences, secondary enucleation and metastases. Methods: Retrospective noncomparative case series. Results: From March 1964 to January 2020, 43 eyes of 40 retinoblastoma patients underwent intraocular surgery. Time interval between last therapy and surgery was 9.5 years on average. Thirty eyes were treated for radiogenic cataract formation with a gain in visual acuity in 63.3%. One child developed an upper eyelid metastasis, 3 showed second primary malignancies (SPM), one a late recurrence and 2 eyes were enucleated. Retinal surgery was performed in 16 eyes, 6 eyes were done as a combined procedure. Indications were radiogenic complications in 10 eyes and a rhegmatogenous retinal detachment in 6 eyes. 43.75% had a postoperative gain in visual acuity. Two patients developed late recurrences, one a SPM and 4 eyes could not be preserved. Conclusion: Surgical therapy in treated retinoblastoma is necessary in isolated cases. In our series cataract surgery was a safe procedure with a good option of a significant increase in visual acuity. Vitreoretinal treated eyes showed a limited gain in visual acuity, a higher risk of late recurrences and a lower globe retention rate. Therefore preoperative high-quality imaging and individual risk-benefit analysis is mandatory.

S. Karger AG, Basel

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