Clinical and behavioral correlates in adult methamphetamine users with childhood exposure to household drug and alcohol use

Christine Buchanan Wanida Rattanasumawong Department of Psychiatry and Neurology, Phramongkutklao Hospital Robert T. Malison Department of Psychiatry, Yale School of Medicine Joel Gelernter Department of Psychiatry, Yale School of Medicine Yaira Nunez Yale School of Medicine Rasmon Kalayasiri Chulalongkorn University

Keywords: methamphetamine, MA, exposure to drug and alcohol use in the household, environmental factors

Abstract

Aims: To describe and compare methamphetamine (MA) users with and without a family history of alcohol or drug () use in the household.

Design:  A total of 1144 Thai-speaking MA users in Thailand were recruited for a cohort study. Cross-sectional baseline data were analyzed according to their exposure to FAOD use (FAOD+/FAOD-). The Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) was utilized to collect baseline socio-demographic information and variables known to be associated with the impact of FAOD use.

Findings:  FAOD+ participants had lower average years of education (p<0.01), fewer average months of employment in the past year (p<0.01) and reported higher rates of self-harm experience (p<0.001), gambling (p=0.018) and antisocial personality disorder  (p=0.015). FAOD+ participants had more severe clinical, adverse consequences. FAOD+ significantly predicted episodes of lifetime MA use (R2 =0.004,  p=0.032), the largest number of drinks ever had in a 24-hour period (R2 =0.01, p=0.001), paranoid experiences ([OR]=1.090, p=0.004), alcohol dependence ([OR]=1.112, p=0.001) and antisocial personality disorder ([OR]=1.139, p=0.015). FAOD+ participants who were exposed to alcohol only were more likely to report a significantly higher number of drinks ever had in a 24-hour periods (p<0.005). Similarly, FAOD+ participants who were exposed to MA use only were significantly more likely to report more frequent use of MA (p<0.005).

Conclusions:  FAOD+ participants were characterized by a generally more severe clinical presentation than FAOD- participants. Moreover, we show the specificity of drug type mattered, with family exposure of alcohol and MA associated with greater subsequent use of the respective drugs.

How to Cite

Buchanan, C., Rattanasumawong, W., Malison, R. T., Gelernter, J., Nunez, Y., & Kalayasiri, R. (2022). Clinical and behavioral correlates in adult methamphetamine users with childhood exposure to household drug and alcohol use. International Journal of Alcohol and Drug Research, 9(2), 77-84. Retrieved from https://ijadr.org/index.php/ijadr/article/view/345

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