Background

Obesity and arteriosclerosis are both independently associated with cardiovascular disease risk. Obesity also may increase arterial stiffness.

Aims

This study aimed to investigate the association between anthropometric indices and non-invasive arterial stiffness parameters, using data from a large population-based cohort of seemingly healthy women and men.

Methods

A total of 5023 eligible participants were included in the study. The pulse wave velocity, central blood pressures and bio-impedance measures were obtained at the time of enrolment. Multiple regression analysis was performed to assess the relationship between anthropometric indices with arterial stiffness parameters.

Results

The mean age of participants was 45.3±8.8 years, 2,368 (47.1%) were males and 2655 (52.8%) were females. The prevalence of participant with underweight, normal weight, overweight and obesity were 0.73%, 33.2%, 48.7% and 17.2% respectively. Systolic and diastolic blood pressure, fatty liver and hypertension were significantly higher in overweight/obesity participants. The overweight/obesity participants had significantly higher pulse wave velocity than the normal-weight group (471.5±42.6 /496.7±47.5 cm/s versus 448.1±41.4 cm/s, P<.001).

Conclusion

The prevalence of diabetes, hypertension, fatty liver disease, chronic lung disease and also kidney stones were significantly higher in overweight and individuals with obesity. Body mass index, body fat mass, waist hip ratio Abdominal Circumference, neck circumference, visceral fat area, total body water, 50kHz-Whole Body Phase Angle are positively correlated with pulse wave velocity. Augmentation index had no significant correlation with body mass index, arm, hip and abdominal circumferences.

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