Can Periodontal Disease Be Considered Linked to Obesity and Lipoinflammation? Mechanisms Involved in the Pathogenesis Occurrence

1.

Pi-Sunyer FX, Becker DM, Bouchard C, Carleton RA, Colditz GA, Dietz WH, et al. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Am J Clin Nutr. 1998;68(4):899–917. https://doi.org/10.1093/ajcn/68.4.899.

Article  Google Scholar 

2.

Ng M, Fleming T, Robinson M, Blake T, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384(9945):766–81. https://doi.org/10.1016/s0140-6736(14)60460-8.

Article  PubMed  PubMed Central  Google Scholar 

3.

Guh DP, Zhang W, Bansback N, Amarsi Z, Laird Birmingham C, Anis AH. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009;9:88. https://doi.org/10.1186/1471-2458-9-88.

Article  PubMed  PubMed Central  Google Scholar 

4.

Chaffee BW, Weston SJ. Association between chronic periodontal disease and obesity: a systematic review and meta-analysis. J Periodontol. 2010;81(12):1708–24. https://doi.org/10.1902/jop.2010.100321.

Article  PubMed  PubMed Central  Google Scholar 

5.

Suvan J, D’Aiuto F, Moles DR, Petrie A, Donos N. Association between overweight/obesity and periodontitis in adults. A systematic review. Obes Rev. 2011;12(5):e381–404. https://doi.org/10.1111/j.1467-789X.2010.00808.x.

Article  PubMed  Google Scholar 

6.

Nishida N, Tanaka M, Hayashi N, Nagata H, Takeshita T, Nakayama K, et al. Determination of smoking and obesity as periodontitis risks using the classification and regression tree method. J Periodontol. 2005;76(6):923–8. https://doi.org/10.1902/jop.2005.76.6.923.

Article  PubMed  Google Scholar 

7.

Ishitaq SM, Rashid H, Hussain Z, Arshad MI, Khan JA. Adiponectin and PAAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease. Rev Endocr Metab Disord. 2019;20(3):253–61. https://doi.org/10.1007/s11154-019-09510-2.

CAS  Article  Google Scholar 

8.

Rodriguez-Rodriguez E, Perea JM, López-Sobaler AM, Ortega RM. Obesity, insulin resistance and increase in adipokines levels: importance of the diet and physical activity. Nutr Hosp. 2009;24(4):415–21.

CAS  PubMed  Google Scholar 

9.

Flores-Lázaro JR, Rodríguez-Martínez E, Rivas-Arancibia S. Metabolic consequences of the functional alterations of adipose tissue in obese patients. Rev Med Hosp Gen Méx. 2011;74(3):157–65.

Google Scholar 

10.

Kim S, Moustaid-Moussa N. Secretory, endocrine and autocrine/paracrine function of the adipocyte. J Nutr. 2000;130(12):S3110–5. https://doi.org/10.1093/jn/130.12.3110S.

Article  Google Scholar 

11.

Ibrahim MM. Subcutaneous and visceral adipose tissue: structural and functional differences. Obes Rev. 2010;11(1):11–8. https://doi.org/10.1111/j.1467-789x.2009.00623.x.

Article  PubMed  Google Scholar 

12.

De Luis DA, González Sagrado M, Conde R, Aller R, Izaola O, Castro MJ. Circulating adipocytokines in morbid obese patients, relation with cardiovascular risk factors and anthropometric parameters. Nutr Hosp. 2011;26(1):91–6.

PubMed  Google Scholar 

13.

De Luis DA, Aller R, Izaola O, Ovalle HF. The serum profile of adipokines in naïve patients with diabetes mellitus type 2 and obesity. J Clin Lab Anal. 2011;25(6):409–13. https://doi.org/10.1002/jcla.20493.

CAS  Article  PubMed  PubMed Central  Google Scholar 

14.

Wellen KE, Hotamisligil GS. Obesity-induced inflammatory changes in adipose tissue. J Clin Invest. 2003;112(12):1785–8. https://doi.org/10.1172/jci20514.

CAS  Article  PubMed  PubMed Central  Google Scholar 

15.

Nishimura S, Manabe I, Nagasaki M, Seo K, Yamashita H, Hosoya Y, et al. In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J Clin Invest. 2008;118:710–21. https://doi.org/10.1172/jci33328.

CAS  Article  PubMed  PubMed Central  Google Scholar 

16.

Xu H, Barnes GT, Yang Q, Tan G, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112(12):1821–30. https://doi.org/10.1172/jci19451.

CAS  Article  PubMed  PubMed Central  Google Scholar 

17.

Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, et al. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell. 2006;124(3):587–99. https://doi.org/10.1016/j.cell.2005.11.040.

CAS  Article  PubMed  Google Scholar 

18.

Mizutani K, Park K, Mima A, Katagiri S, King GL. Obesity-associtated gingival vascular inflammation and insulin resistance. J Dent Res. 2014;93(6):596–601. https://doi.org/10.1177/0022034514532102.

CAS  Article  PubMed  PubMed Central  Google Scholar 

19.

Watanabe K, Iizuka T, Adeleke A, Pham L, Shlimon AE, Yasin M, et al. Involvement of toll-like receptor 4 in alveolar bone loss and glucose homeostasis in experimental periodontitis. J Periodontal Res. 2011;46(1):21–30. https://doi.org/10.1111/j.1600-0765.2010.01304.x.

CAS  Article  PubMed  Google Scholar 

20.

Cunha JS, Ferreira VM, Naves MA, Boim MA. Effects of high glucose and high insulin concentrations on osteoblast function in vitro. Cell Tissue Res. 2014;358(1):249–56. https://doi.org/10.1007/s00441-014-1913-x.

CAS  Article  PubMed  Google Scholar 

21.

Zhang L, Meng S, Tu Q, Yu L, Tang Y, Dard MM, et al. Adiponectin ameliorates experimental periodontitis in diet-induced obesity mice. PLoS One. 2014;9(5):e97824. https://doi.org/10.1371/journal.pone.0097824.

CAS  Article  PubMed  PubMed Central  Google Scholar 

22.

Goto H, Hozumi A, Osaki M, Fukushima T, Sakamoto K, Yonekura A, et al. Primary human bone marrow adipocytes support TNF-α-induced osteoclast differentiation and function through RANKL expression. Cytokine. 2011;56(3):662–8. https://doi.org/10.1016/j.cyto.2011.09.005.

CAS  Article  PubMed  Google Scholar 

23.

Akram Z, Abduljabbar T, Abu Hassan MI, Javed F, Vohra F. Cytokine profile in chronic periodontitis patients with and without obesity: a systematic review and meta-analysis. Dis Markers. 2016;2016:1–12. https://doi.org/10.1155/2016/4801418.

CAS  Article  Google Scholar 

24.

Akram Z, Safii SH, Vaithilingam RD, Baharuddin NA, Javed F, Vohra F. Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis. Clin Oral Investig. 2016;20(5):903–14. https://doi.org/10.1007/s00784-016-1793-4.

Article  PubMed  Google Scholar 

25.

Gerber FA, Sahrmann P, Schmidlin OA, Heumann C, Beer JH, Schmidlin PR. Influence of obesity on the outcome of non-surgical periodontal therapy - a systematic review. BMC Oral Health. 2016;16(1):90. https://doi.org/10.1186/s12903-016-0272-2.

Article  PubMed  PubMed Central  Google Scholar 

26.

Keller A, Rohde JF, Raymond K, Heitmann BL. Association between periodontal disease and overweight and obesity: a systematic review. J Periodontol. 2015;86(6):766–76. https://doi.org/10.1902/jop.2015.140589.

Article  PubMed  Google Scholar 

27.

Li LW, Wong HM, Sun L, Wen YF, McGrath CP. Anthropometric measurements and periodontal diseases in children and adolescents: a systematic review and meta-analysis. Adv Nutr. 2015;6(6):828–41. https://doi.org/10.3945/an.115.010017.

CAS  Article  PubMed  PubMed Central  Google Scholar 

28.

Martens L, De SS, Yusof MY, Rajasekharan S. Association between overweight/obesity and periodontal disease in children and adolescents: a systematic review and meta-analysis. Eur Arch Paediatr Dent. 2017;18(2):69–82. https://doi.org/10.1007/s40368-017-0272-1.

CAS  Article  PubMed  Google Scholar 

29.

Martinez-Herrera M, Silvestre-Rangil J, Silvestre FJ. Association between obesity and periodontal disease. A systematic review of epidemiological studies and controlled clinical trials. Med Oral Patol Oral Cir Bucal. 2017;22(6):e708–15. https://doi.org/10.4317/medoral.21786.

CAS  Article  PubMed  PubMed Central  Google Scholar 

30.

De Moura-Grec PG, Marsicano JA, Paz de Carvalho CA, Sales-Peres SH. Obesity and periodontitis: systematic review and meta-analysis. Cien Saude Colet. 2014;19(6):1763–72. https://doi.org/10.1590/1413-81232014196.13482013.

Article  PubMed  Google Scholar 

31.

Nascimento GG, Leite FR, Conceicao DA, Ferrua CP, Singh A, Demarco FF. Is there a relationship between obesity and tooth loss and edentulism? A systematic review and meta-analysis. Obes Rev. 2016;17(7):587–98. https://doi.org/10.1111/obr.12418.

CAS  Article  PubMed  Google Scholar 

32.

Nascimento GG, Leite FR, Correa MB, Peres MA, Demarco FF. Does periodontal treatment have an effect on clinical and immuno-logical parameters of periodontal disease in obese subjects? A systematic review and meta-analysis. Clin Oral Investig. 2016;20(4):639–47. https://doi.org/10.1007/s00784-015-1678-y.

Article  PubMed  Google Scholar 

33.

Nascimento GG, Leite FR, Do LG, et al. Is weight gain associated with the incidence of periodontitis? A systematic review and meta-analysis. J Clin Periodontol. 2015;42(6):495–505. https://doi.org/10.1111/jcpe.12417.

Article  PubMed  Google Scholar 

34.

Papageorgiou SN, Reichert C, Jager A, Deschner J. Effect of over- weight/obesity on response to periodontal treatment: systematic review and a meta-analysis. J Clin Periodontol. 2015;42(3):247–61. https://doi.org/10.1111/jcpe.12365.

Article  PubMed  Google Scholar 

35.

Suvan JE, Finer N, D’Aiuto F. Periodontal complications with obesity. Periodontol 2000. 2018;78(1):98–128. https://doi.org/10.1111/prd.12239.

Article  PubMed  Google Scholar 

36.

Nascimento GG, Peres KG, Mittinty MN, Mejia GC, Silva DA, Gonzalez-Chica D, et al. Obesity and periodontal outcomes: a population-based cohort study in Brazil. J Periodontol. 2017;88(1):50–8. https://doi.org/10.1902/jop.2016.160361.

Article  PubMed  Google Scholar 

37.

Reid IR. Fat and bone. Arch Biochem Biophys. 2010;503(1):20–7. https://doi.org/10.1016/j.abb.2010.06.027.

CAS  Article  PubMed  Google Scholar 

38.

Neumann T, Lodes S, Kästner B, Franke S, Kiehntopf M, Lehmann T, et al. Osteocalcin, adipokines and their associations with glucose metabolism in type 1 diabetes. Bone. 2016;82:50–5. https://doi.org/10.1016/j.bone.2015.04.017.

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