1. World Health Organization. Global Spending on Health: A World in Transition. See https://apps.who.int/iris/handle/10665/330357 (last checked 13 April 2021).
Google Scholar2. Dall, TM, Gallo, PD, Chakrabarti, R, West, T, Semilla, AP, Storm, MV. An aging population and growing disease burden will require a large and specialized health care workforce by 2025. Health Aff (Millwood) 2013; 32: 2013–2020.
Google Scholar | Crossref | Medline3. Mason, A . New medicines in primary care: a review of influences on general practitioner prescribing. J Clin Pharm Ther 2008; 33: 1–10.
Google Scholar | Crossref | Medline | ISI4. Wathen B and Dean T. An evaluation of the impact of NICE guidance on GP prescribing. Br J Gen Pract 2004; 54: 103–107.
Google Scholar5. Harrison, S, Dowswell, G, Wright, J, Russell, I. General practitioners’ uptake of clinical practice guidelines: a qualitative study. J Health Serv Res Policy 2003; 8: 149–153.
Google Scholar | SAGE Journals6. Bedson, J, Belcher, J, Martino, OI, Ndlovu, M, Rathod, T, Walters, K, et al. The effectiveness of national guidance in changing analgesic prescribing in primary care from 2002 to 2009: an observational database study. Eur J Pain 2013; 17: 434–443.
Google Scholar | Crossref | Medline7. Walker, AJ, Pretis, F, Powell-Smith, A, Goldacre, B. Variation in responsiveness to warranted behaviour change among NHS clinicians: novel implementation of change detection methods in longitudinal prescribing data. BMJ 2019; 367: l5205–l5205.
Google Scholar | Crossref | Medline8. Public Health Matters. Health Matters: Preventing Cardiovascular Disease. See https://publichealthmatters.blog.gov.uk/2019/02/14/health-matters-preventing-cardiovascular-disease/ (last checked 13 April 2021).
Google Scholar9. Luengo‐Fernández, R, Leal, J, Gray, A, Petersen, S, Rayner, M. Cost of cardiovascular diseases in the United Kingdom. Heart 2006; 92: 1384–1384.
Google Scholar | Crossref | Medline | ISI10. NICE. Statins for the Prevention of Cardiovascular Events: Guidance. See https://www.nice.org.uk/guidance/ta94 (last checked 13 April 2021).
Google Scholar11. NICE. Lipid Modification: Cardiovascular Risk Assessment and the Modification of Blood Lipids for the Primary and Secondary Prevention of Cardiovascular Disease: Guidance. See https://www.nice.org.uk/guidance/cg67 (last checked 13 April 2021).
Google Scholar12. NICE. Cardiovascular Disease: Risk Assessment and Reduction, Including Lipid Modification: Guidance and Guidelines. See https://www.nice.org.uk/guidance/cg181/chapter/appendix-a-grouping-of-statins (last checked 13 April 2021).
Google Scholar13. Correa, A, Hinton, W, McGovern, A, van Vlymen, J, Yonova, I, Jones, S, et al. Royal College of General Practitioners Research and Surveillance Centre (RCGP RSC) sentinel network: a cohort profile. BMJ Open 2016; 6: e011092–e011092.
Google Scholar | Crossref | Medline14. Hinton, W, McGovern, A, Coyle, R, Han, TS, Sharma, P, Correa, A, et al. Incidence and prevalence of cardiovascular disease in English primary care: a cross-sectional and follow-up study of the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC). BMJ Open 2018; 8: e020282–e020282.
Google Scholar | Crossref | Medline15. NHS Digital. Prescription Cost Analysis. See https://digital.nhs.uk/data-and-information/publications/statistical/prescription-cost-analysis (last checked 13 April 2021).
Google Scholar16. Law, MR, Wald, NJ, Rudnicka, AR. Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ 2003; 326: 1423–1423.
Google Scholar | Crossref | Medline17. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins. The Lancet 2005; 366: 1267–1278.
Google Scholar | Crossref | Medline | ISI18. Moon, JC, Bogle, RG. Switching statins. BMJ 2006; 332: 1344–1345.
Google Scholar | Crossref | Medline19. Armitage, J . The safety of statins in clinical practice. The Lancet 2007; 370: 1781–1790.
Google Scholar | Crossref | Medline | ISI20. Amarenco, P, Labreuche, J. Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention. Lancet Neurol 2009; 8: 453–463.
Google Scholar | Crossref | Medline | ISI21. Mike Knapper, Dr Inga-Marlene, Ian Giles and Caroline May. Medicinal product regulation and product liability in the UK (England and Wales): overview. Practical Law. See http://uk.practicallaw.thomsonreuters.com/3-500-9763?transitionType=Default&contextData=(sc.Default)&firstPage=true&bhcp=1 (last checked 23 April 2021.).
Google Scholar22. Avery T, Barber N, Ghaleb M, Franklin D, Armstrong S, Crowe S, et al. Investigating the prevalence and causes of prescribing errors in general practice: The PRACtICe Study (PRevalence And Causes of prescrIbing errors in general practiCe): a report for the GMC. See https://www.gmc-uk.org/-/media/gmc-site-images/about/investigatingtheprevalenceandcausesofprescribingerrorsingeneralpracticethepracticestudyreoprtmay2012.pdf?la=en&hash=21B05525C5FEF17C832EF985D8636C08E524A6C9 (last checked 25 October 2021).
Google Scholar23. Goldacre, B, Reynolds, C, Powell-Smith, A, Walker, AJ, Yates, TA, Croker, R, et al. Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data. BMJ Open 2019; 9: e026886–e026886.
Google Scholar | Crossref | Medline24. Matthews, A, Herrett, E, Gasparrini, A, Van Staa, T, Goldacre, B, Smeeth, L, et al. Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data. BMJ 2016; 353: i3283–i3283.
Google Scholar | Crossref | Medline25. Ju, A, Hanson, CS, Banks, E, Korda, R, Craig, JC, Usherwood, T, et al. Patient beliefs and attitudes to taking statins: systematic review of qualitative studies. Br J Gen Pract 2018; 68: e408–e419.
Google Scholar | Crossref | Medline26. Hire, C, Rushforth, B. General practitioners’ views on using a prescribing substitution application (ScriptSwitch®). J Innov Health Inform 2013; 21: 1–11.
Google Scholar27. NICE strategy 2021 to 2026: Dynamic, Collaborative, Excellent. See https://www.nice.org.uk/about/who-we-are/corporate-publications/the-nice-strategy-2021-to-2026 (last checked 13 April 2021).
Google Scholar