Activin A and Follistatin Serum Concentrations in Breast Augmentation Patients: Concentrations sériques d'activine A et de follistatine chez les patientes ayant une augmentation mammaire

1. Hall-Findlay, EJ . Breast implant complication review: double capsules and late seromas. Plast Reconstr Surg. 2011;127(1):56–66.
Google Scholar | Crossref | Medline | ISI2. Spear, SL, Rottman, SJ, Glicksman, C, Brown, M, Al-Attar, A. Late seromas after breast implants: theory and practice. Plast Reconstr Surg. 2012;130(2):423-435.
Google Scholar | Crossref | Medline3. Henriksen, TF, Hölmich, LR, Fryzek, JP, et al. Incidence and severity of short-term complications after breast augmentation: results from a nationwide breast implant registry. Ann Plast Surg. 2003;51(6):531-539.
Google Scholar | Crossref | Medline4. Doren, EL, Pierpont, YN, Shivers, SC, Berger, LH. Comparison of allergan, mentor, and sientra contoured cohesive Gel breast implants: a single Surgeon's 10-Year Experience. Plast Reconstr Surg. 2015;136(5):957-966.
Google Scholar | Crossref | Medline5. Hammond, DC, Canady, JW, Love, TR, Wixtrom, RN, Caplin, DA. Mentor contour profile Gel implants: clinical outcomes at 10 years. Plast Reconstr Surg. 2017;140(6):1142-1150.
Google Scholar | Crossref | Medline6. Siggelkow, W, Faridi, A, Spiritus, K, Klinge, U, Rath, W, Klosterhalfen, B. Histological analysis of silicone breast implant capsules and correlation with capsular contracture. Biomaterials. 2003;24(6):1101-1109.
Google Scholar | Crossref | Medline7. Kasper, CS . Histologic features of breast capsules reflect surface configuration and composition of silicone bag implants. Am J Clin Pathol. 1994;102(5):655-659.
Google Scholar | Crossref | Medline8. Moyer, HR, Ghazi, BH, Losken, A. The effect of silicone gel bleed on capsular contracture: a generational study. Plast Reconstr Surg. 2012;130(4):793-800.
Google Scholar | Crossref | Medline9. Zeplin, PH, Corduff, N. Influence of patient age on capsular contracture after aesthetic breast augmentation. Plast Surg (Oakv). 2015;23(2):67-69.
Google Scholar | SAGE Journals10. Iwuagwu, FC, Frame, JD. Silicone breast implants: complications. Br J Plast Surg. 1997;50(8):632-636.
Google Scholar | Crossref | Medline11. Prantl, L, Schreml, S, Fichtner-Feigl, S, et al. Clinical and morphological conditions in capsular contracture formed around silicone breast implants. Plast Reconstr Surg. 2007;120(1):275-284.
Google Scholar | Crossref | Medline | ISI12. Garner, WL, Rittenberg, T, Ehrlich, HP, et al. Hypertrophic scar fibroblasts accelerate collagen gel contraction. Wound Repair Regen. 1995;3(2):185-191.
Google Scholar | Crossref | Medline13. Ehrlich, HP . Wound closure: evidence of cooperation between fibroblasts and collagen matrix. Eye (Lond. 1988;2[2]:149-157.
Google Scholar | Crossref | Medline14. Betarbet, U, Blalock, TW. Keloids: a review of etiology, prevention, and treatment. J Clin Aesthet Dermatol. 2020;13(2):33-43.
Google Scholar | Medline15. Huang, C, Ogawa, R. Fibroproliferative disorders and their mechanobiology. Connect Tissue Res. 2012;53(3):187-196.
Google Scholar | Crossref | Medline16. Derynck, R, Zhang, YE. Smad-dependent and smad-independent pathways in TGF-beta family signalling. Nature. 2003;425(6958):577-584.
Google Scholar | Crossref | Medline | ISI17. Takagi, K, Kawaguchi, Y, Kawamoto, M, et al. Activation of the activin A-ALK-smad pathway in systemic sclerosis. J Autoimmun. 2001;36(3–4):181-188.
Google Scholar | Crossref18. de Kretser, DM, O’Hehir, RE, Hardy, CL, Hedger, MP. The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair. Mol Cell Endocrinol. 2012;359(1–2):101-106.
Google Scholar | Crossref | Medline19. Ohga, E, Matsuse, T, Teramoto, S, Ouchi, Y. Activin receptors are expressed on human lung fibroblast and activin A facilitates fibroblast-mediated collagen gel contraction. Life Sci. 2000;66(17):1603-1613.
Google Scholar | Crossref | Medline20. Ohga, E, Matsuse, T, Teramoto, S, et al. Effects of activin A on proliferation and differentiation of human lung fibroblasts. Biochem Biophys Res Commun. 1996;228(2):391-396.
Google Scholar | Crossref | Medline21. Sugiyama, M, Ichida, T, Sato, T, Ishikawa, T, Matsuda, Y, Asakura, H. Expression of activin A is increased in cirrhotic and fibrotic rat livers. Gastroenterology. 1998;114(3):550-558.
Google Scholar | Crossref | Medline22. Hedger, MP, Winnall, WR, Phillips, DJ, de Kretser, DM. The regulation and functions of activin and follistatin in inflammation and immunity. Vitam Horm. 2011;85:255-297.
Google Scholar | Crossref | Medline23. Hedger, MP, de Kretser, DM. The activins and their binding protein, follistatin-diagnostic and therapeutic targets in inflammatory disease and fibrosis. Cytokine Growth Factor Rev. 2013;24(3):285-295.
Google Scholar | Crossref | Medline24. Fumagalli, M, Musso, T, Vermi, W, et al. Imbalance between activin A and follistatin drives postburn hypertrophic scar formation in human skin. Exp Dermatol. 2007;16(7):600-610.
Google Scholar | Crossref | Medline25. Frenkiel, BA, Temple-Smith, P, de Kretser, D, Southwick, GJ. Follistatin and the breast implant capsule. Plast Reconstr Surg Glob Open. 2017;5(3):e1258.
Google Scholar | Crossref | Medline26. Henriksen, TF, Fryzek, JP, Hölmich, LR, et al. Surgical intervention and capsular contracture after breast augmentation: a prospective study of risk factors. Ann Plast Surg. 2005;54(4):343-351.
Google Scholar | Crossref | Medline27. Wolfram, D, Rainer, C, Niederegger, H, Piza, H, Wick, G. Cellular and molecular composition of fibrous capsules formed around silicone breast implants with special focus on local immune reactions. J Autoimmun. 2004;23(1):81-91.
Google Scholar | Crossref | Medline28. Berman, B, Maderal, A, Raphael, B. Keloids and hypertrophic scars: pathophysiology, classification, and treatment. Dermatol Surg. 2017;43(Suppl 1):S3-S18.
Google Scholar | Crossref | Medline29. Ma, TT, Meng, XM. TGF-β/ smad and renal fibrosis. Adv Exp Med Biol. 2019;1165:347-364.
Google Scholar | Crossref | Medline30. Rosenbloom, J, Macarak, E, Piera-Velazquez, S, Jimenez, SA. Human fibrotic diseases: current challenges in fibrosis research. Methods Mol Biol. 2017;1627:1-23.
Google Scholar | Crossref | Medline31. Olsen, OE, Hella, H, Elsaadi, S, Jacobi, C, Martinez-Hackert, E, Holien, T. Activins as dual specificity TGF-β family molecules: sMAD-activation via activin- and BMP-type 1 receptors. Biomolecules. 2020;10(4):519.
Google Scholar | Crossref32. Chin, GS, Liu, W, Peled, Z, et al. Differential expression of transforming growth factor-beta receptors I and II and activation of smad 3 in keloid fibroblasts. Plast Reconstr Surg. 2001;108(2):423-429.
Google Scholar | Crossref | Medline | ISI33. Mukhopadhyay, A, Chan, SY, Lim, IJ, Phillips, DJ, Phan, TT. The role of the activin system in keloid pathogenesis. Am J Physiol Cell Physiol. 2007;292(4):C1331-C1338.
Google Scholar | Crossref | Medline34. Khoury, RH, Wang, QF, Crowley, WF, et al. Serum follistatin levels in women: evidence against an endocrine function of ovarian follistatin. J Clin Endocrinol Metab. 1995;80(4):1361-1368.
Google Scholar | Medline35. de Kretser, DM, Bensley, JG, Pettilä, V, et al. Serum activin A and B levels predict outcome in patients with acute respiratory failure: a prospective cohort study. Crit Care. 2013;17(5):R263.
Google Scholar | Crossref | Medline36. Dohi, T, Ejima, C, Kato, R, et al. Therapeutic potential of follistatin for colonic inflammation in mice. Gastroenterology. 2005;128(2):411-423.
Google Scholar | Crossref | Medline37. Zeplin, PH, Larena-Avellaneda, A, Jordan, MC, Laske, M, Schmidt, K. Phosphorylcholine-coated silicone implants - effect on inflammatory response and fibrous capsule formation. Ann Plast Surg. 2010;65(6):560-564.
Google Scholar | Crossref | Medline38. Zeplin, PH, Larena-Avellaneda, A, Schmidt, K. Surface modification of silicone breast implants by binding the antifibrotic drug halofuginone reduces capsular fibrosis. Plast Reconstr Surg. 2010;126(1):266-274.
Google Scholar | Crossref | Medline39. Zeplin, PH, Berninger, AK, Maksimovikj, NC, van Gelder, P, Scheibel, T, Walles, H. Improvement of silicone implants with spider silk coating: immunohistochemical analysis of capsule formation. Handchir Mikrochir Plast Chir. 2014;46(6):336-341.
Google Scholar | Medline40. Zeplin, PH, Maksimovikj, NC, Jordan, MC, et al. Spider silk as a bioshield to reduce periprosthetic fibrous capsule formation. Adv Funct Mat. 2014;24(18):2658-2666.
Google Scholar | Crossref41. Zeplin, PH . Reduction of cutaneous scar formation by halofuginone-eluting silicone gel sheets: a controlled study on nude mice. Ann Plast Surg. 2012;68(3):271-275.
Google Scholar | Crossref | Medline42. Muttukrishna, S, Fowler, PA, George, L, Groome, NP, Knight, PG. Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J Clin Endocrinol Metab. 1996;81(9):3328-3334.
Google Scholar | Medline43. Wakatsuki, M, Shintani, Y, Abe, M, Liu, ZH, Shitsukawa, K, Saito, S. Immunoradiometric assay for follistatin: serum immunoreactive follistatin levels in normal adults and pregnant women. J Clin Endocrinol Metab. 1996;81(2):630-634.
Google Scholar | Medline44. Woodruff, TK, Sluss, P, Wang, E, Janssen, I, Mersol-Barg, MS. Activin A and follistatin are dynamically regulated during human pregnancy. J Endocrinol. 1997;152(2):167-174.
Google Scholar | Crossref | Medline45. Harada, K, Shintani, Y, Sakamoto, Y, Wakatsuki, M, Shitsukawa, K, Saito, S. Serum immunoreactive activin A levels in normal subjects and patients with various diseases. J Clin Endocrinol Metab. 1996;81(6):2125-2130.
Google Scholar | Medline46. Luisi, S, Battaglia, C, Florio, P, et al. Activin A and inhibin B in extra-embryonic coelomic and amniotic fluids, and maternal serum in early pregnancy. Placenta. 1998;19(5–6):435-438.
Google Scholar | Crossref | Medline47. Muttukrishna, S, Knight, PG, Groome, NP, Redman, CW, Ledger, WL. Activin A and inhibin A as possible endocrine markers for pre-eclampsia. Lancet. 1997;349(9061):1285-1288.
Google Scholar | Crossref | Medline48. Phillips, DJ, Jones, KL, Scheerlinck, JY, Hedger, MP, de Kretser, DM. Evidence for activin A and follistatin involvement in the systemic inflammatory response. Mol Cell Endocrinol. 2001;180(1–2):155-162.
Google Scholar | Crossref | Medline49. Lee, JK, Choi, SM, Lee, J, et al. Serum activin-A as a predictive and prognostic marker in critically ill patients with sepsis. Respirology. 2016;21(5):891-897.
Google Scholar | Crossref | Medline

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