1. Bacigaluppi, M, Semerano, A, Gullotta, GS, et al. Insights from thrombi retrieved in stroke due to large vessel occlusion. J Cereb Blood Flow Metab 2019; 39: 1433–1451.
Google Scholar | SAGE Journals | ISI2. Brinjikji, W, Duffy, S, Burrows, A, et al. Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome: A systematic review. J Neurointerv Surg 2017; 9: 529–534.
Google Scholar | Crossref | Medline3. De Meyer, SF, Andersson, T, Baxter, B, et al. Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions. Int J Stroke 2017; 12: 606–614.
Google Scholar | SAGE Journals | ISI4. Kirchhof, K, Welzel, T, Mecke, C, et al. Differentiation of white, mixed, and red thrombi: Value of CT in estimation of the prognosis of thrombolysis phantom study. Radiology 2003; 228: 126–130.
Google Scholar | Crossref | Medline | ISI5. Besachio, DA, Quigley, EP, Shah, LM, et al. Noncontrast computed tomographic Hounsfield unit evaluation of cerebral venous thrombosis: A quantitative evaluation. Neuroradiology 2013; 55: 941–945.
Google Scholar | Crossref | Medline6. Brogan, GX Bench to bedside: Pathophysiology of acute coronary syndromes and implications for therapy. Acad Emerg Med 2002; 9: 1029–1044.
Google Scholar | Crossref | Medline7. Minnerup, J, Kleinschnitz, C. Visualization of clot composition in ischemic stroke: Do we get what we see? Stroke 2011; 42: 1193–1194.
Google Scholar | Crossref | Medline | ISI8. Mehta, BP, Nogueira, RG. Should clot composition affect choice of endovascular therapy? Neurology 2012; 79: s63–s67.
Google Scholar | Crossref | Medline9. Tan, JC, Dillon, WP, Liu, S, et al. Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients. Ann Neurol 2007; 61: 533–543.
Google Scholar | Crossref | Medline | ISI10. Barber, PA, Demchuk, AM, Zhang, J, et al. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score. Lancet 2000; 355: 1670–1674.
Google Scholar | Crossref | Medline | ISI11. Tung, EL, McTaggart, RA, Baird, GL, et al. Rethinking thrombolysis in cerebral infarction 2b: Which thrombolysis in cerebral infarction scales best define near complete recanalization in the modern thrombectomy era? Stroke 2017; 48: 2488–2493.
Google Scholar | Crossref | Medline12. Amarenco, P, Bogousslavsky, J, Caplan, LR, et al. The ASCOD phenotyping of ischemic stroke (updated ASCO phenotyping). Cerebrovasc Dis 2013; 36: 1–5.
Google Scholar | Crossref | Medline | ISI13. Hart, RG, Diener, HC, Coutts, SB, et al. Embolic strokes of undetermined source: The case for a new clinical construct. Lancet Neurol 2014; 13: 429–438.
Google Scholar | Crossref | Medline | ISI14. Mortimer, AM, Little, DH, Minhas, KS, et al. Thrombus length estimation in acute ischemic stroke: A potential role for delayed contrast enhanced CT. J Neurointerv Surg 2014; 6: 244–248.
Google Scholar | Crossref | Medline15. Qazi, EM, Sohn, SI, Mishra, S, et al. Thrombus characteristics are related to collaterals and angioarchitecture in acute stroke. Can J Neurol Sci 2015; 42: 381–388.
Google Scholar | Crossref | Medline | ISI16. Liebeskind, DS, Sanossian, N, Yong, WH, et al. CT and MRI early vessel signs reflect clot composition in acute stroke. Stroke 2011; 42: 1237–1243.
Google Scholar | Crossref | Medline | ISI17. Di Meglio, L, Desilles, JP, Ollivier, V, et al. Acute ischemic stroke thrombi have an outer shell that impairs fibrinolysis. Neurology 2019; 93: e1686–e1698.
Google Scholar | Crossref | Medline18. Puig, J, Pedraza, S, Demchuk, A, et al. Quantification of thrombus Hounsfield units on noncontrast CT predicts stroke subtype and early recanalization after intravenous recombinant tissue plasminogen activator. AJNR Am J Neuroradiol 2012; 33: 90–96.
Google Scholar | Crossref | Medline | ISI19. Moftakhar, P, English, JD, Cooke, DL, et al. Density of thrombus on admission CT predicts revascularization efficacy in large vessel occlusion acute ischemic stroke. Stroke 2013; 44: 243–245.
Google Scholar | Crossref | Medline | ISI20. Niesten, JM, van der Schaaf, IC, Biessels, GJ, et al. Relationship between thrombus attenuation and different stroke subtypes. Neuroradiology 2013; 55: 1071–1079.
Google Scholar | Crossref | Medline | ISI21. Niesten, JM, van der Schaaf, IC, van der Graaf, Y, et al. Predictive value of thrombus attenuation on thin-slice non-contrast CT for persistent occlusion after intravenous thrombolysis. Cerebrovasc Dis 2014; 37: 116–122.
Google Scholar | Crossref | Medline22. Topcuoglu, MA, Arsava, EM, Kursun, O, et al. The utility of middle cerebral artery clot density and burden assessment by noncontrast computed tomography in acute ischemic stroke patients treated with thrombolysis. J Stroke Cerebrovasc Dis 2014; 23: e85–e91.
Google Scholar | Crossref | Medline | ISI23. Mokin, M, Morr, S, Natarajan, SK, et al. Thrombus density predicts successful recanalization with Solitaire stent retriever thrombectomy in acute ischemic stroke. J Neurointerv Surg 2015; 7: 104–107.
Google Scholar | Crossref | Medline | ISI24. Santos, EM, Yoo, AJ, Beenen, LF, et al. Observer variability of absolute and relative thrombus density measurements in patients with acute ischemic stroke. Neuroradiology 2016; 58: 133–139.
Google Scholar | Crossref | Medline25. Kim, EY, Heo, JH, Lee, SK, et al. Prediction of thrombolytic efficacy in acute ischemic stroke using thin-section noncontrast CT. Neurology 2006; 67: 1846–1848.
Google Scholar | Crossref | Medline26. Mackman, N. New insights into the mechanisms of venous thrombosis. J Clin Invest 2012; 122: 2331–2336.
Google Scholar | Crossref | Medline | ISI27. Fogelson, AL, Neeves, KB. Fluid mechanics of blood clot formation. Annu Rev Fluid Mech 2015; 47: 377–403.
Google Scholar | Crossref | Medline28. Berndt, M, Friedrich, B, Maegerlein, C, et al. Thrombus permeability in admission computed tomographic imaging indicates stroke pathogenesis based on thrombus histology. Stroke 2018; 49: 2674–2682.
Google Scholar | Crossref | Medline29. Benson, JC, Fitzgerald, ST, Kadirvel, R, et al. Clot permeability and histopathology: Is a clot’s perviousness on CT imaging correlated with its histologic composition? J Neurointerv Surg 2020; 12: 38–42.
Google Scholar | Crossref | Medline30. Ye, G, Cao, R, Lu, J, et al. CT-based higher thrombus density is associated with secondary embolism during mechanical thrombectomy: A preliminary observation. J Stroke Cerebrovasc Dis 2019; 28: 104311.
Google Scholar | Crossref | Medline31. Laridan, E, Denorme, F, Desender, L, et al. Neutrophil extracellular traps in ischemic stroke thrombi. Ann Neurol 2017; 82: 223–232.
Google Scholar | Crossref | Medline32. Novotny, J, Oberdieck, P, Titova, A, et al. Thrombus NET content is associated with clinical outcome in stroke and myocardial infarction. Neurology 2020; 94: e2346–e2360.
Google Scholar | Crossref | Medline33. Genchi, A, Semerano, A, Gullotta, GS, et al. Cerebral thrombi of cardioembolic etiology have an increased content of neutrophil extracellular traps. J Neurol Sci 2021; 423: 117355.
Google Scholar | Crossref | Medline