Cognitive effects of vortioxetine in older adults: a systematic review

1. Fiske, A, Wetherell, JL, Gatz, M. Depression in older adults. Annu Rev Clin Psychol 2009; 5: 363–389.
Google Scholar | Crossref | Medline | ISI2. Aziz, R, Steffens, D. Overlay of late-life depression and cognitive impairment. Focus (Am Psychiatr Publ) 2017; 15: 35–41.
Google Scholar | Medline3. Alexopoulos, GS . Mechanisms and treatment of late-life depression. Transl Psychiatry 2019; 9: 188.
Google Scholar | Crossref | Medline4. Hanninen, T, Koivisto, K, Reinikainen, KJ, et al. Prevalence of ageing-associated cognitive decline in an elderly population. Age Ageing 1996; 25: 201–205.
Google Scholar5. Bettio, LEB, Rajendran, L, Gil-Mohapel, J. The effects of aging in the hippocampus and cognitive decline. Neurosci Biobehav Rev 2017; 79: 66–86.
Google Scholar | Crossref | Medline6. Cirrito, JR, Disabato, BM, Restivo, JL et al. Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans. Proc Natl Acad Sci U S A 2011; 108: 14968–14973.
Google Scholar7. Bartels, C, Wagner, M, Wolfsgruber, S, et al. Impact of SSRI therapy on risk of conversion from mild cognitive impairment to Alzheimer’s dementia in individuals with previous depression. Am J Psychiatry 2018; 175: 232–241.
Google Scholar8. Raskin, J, Wiltse, CG, Siegal, A, et al. Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial. Am J Psychiatry 2007; 164: 900–909.
Google Scholar9. Lavretsky, H, Reinlieb, M, St Cyr, N et al. Citalopram, methylphenidate, or their combination in geriatric depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry 2015; 172: 561–569.
Google Scholar | Crossref | Medline | ISI10. Blumberg, MJ, Vaccarino, SR, McInerney, SJ. Procognitive effects of antidepressants and other therapeutic agents in major depressive disorder: a systematic review. J Clin Psychiatry 2020; 81: 19r13200.
Google Scholar | Crossref | Medline11. Sanchez, C, Asin, KE, Artigas, F. Vortioxetine, a novel antidepressant with multimodal activity: review of preclinical and clinical data. Pharmacol Ther 2015; 145: 43–57.
Google Scholar | Crossref | Medline | ISI12. D’Agostino, A, English, CD, Rey, JA. Vortioxetine (brintellix): a new serotonergic antidepressant. P T 2015; 40: 36–40.
Google Scholar | Medline13. Katona, C, Hansen, T, Olsen, CK. A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder. Int Clin Psychopharmacol 2012; 27: 215–223.
Google Scholar | Crossref | Medline | ISI14. Cumbo, E, Cumbo, S, Torregrossa, S, et al Treatment effects of vortioxetine on cognitive functions in mild Alzheimer’s disease patients with depressive symptoms: a 12 month, open-label, observational study. J Prev Alzheimers Dis 2019; 6: 192–197.
Google Scholar | Medline15. Lenze, EJ, Stevens, A, Waring, JD, et al Augmenting computerized cognitive training with vortioxetine for age-related cognitive decline: a randomized controlled trial [published correction appears in Am J Psychiatry. 2020;177(6):556]. Am J Psychiatry 2020; 177: 548–555.
Google Scholar16. Guyatt, GH, Oxman, AD, Vist, GE, et al GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008; 336: 924–926.
Google Scholar | Crossref | Medline17. Sharp, R . The Hamilton rating scale for depression. Occup Med (Lond) 2015; 65: 340.
Google Scholar | Crossref | Medline18. Arevalo-Rodriguez, I, Smailagic, N, Roqué, I, Figuls, M, et al Mini-Mental State Examination (MMSE) for the detection of Alzheimer’s disease and other dementias in people with mild cognitive impairment (MCI). Cochrane Database Syst Rev 2015; 2015: CD010783.
Google Scholar19. Jaeger, J . Digit Symbol Substitution test: the case for sensitivity over specificity in neuropsychological testing. J Clin Psychopharmacol 2018; 38: 513–519.
Google Scholar | Crossref | Medline20. Rosano, C, Perera, S, Inzitari, M, et al. Digit Symbol Substitution test and future clinical and subclinical disorders of cognition, mobility and mood in older adults. Age Ageing 2016; 45: 688–695.
Google Scholar21. Vakil, E, Blachstein, H. Rey Auditory-Verbal Learning Test: structure analysis. J Clin Psychol 1993; 49: 883–890.
Google Scholar | Crossref | Medline | ISI22. Tombaugh, TN, McIntyre, NJ. The mini-mental state examination: a comprehensive review. J Am Geriatr Soc 1992; 40: 922–935.
Google Scholar | Crossref | Medline | ISI23. Heaton, RK, Akshoomoff, N, Tulsky, D, et al. Reliability and validity of composite scores from the NIH Toolbox Cognition Battery in adults. J Int Neuropsychol Soc 2014; 20: 588–598.
Google Scholar24. H. Lundbeck A/S . Brintellix (package insert). Denmark: H. Lundbeck A/S, 2013.
Google Scholar25. Takeda Pharmaceuticals America, Inc . Trintellix (package insert). Deerfield, IL: Takeda Pharmaceutical America, Inc., 2013.
Google Scholar26. Deakin, JB, Rahman, S, Nestor, PJ, et al Paroxetine does not improve symptoms and impairs cognition in frontotemporal dementia: a double-blind randomized controlled trial. Psychopharmacology (Berl) 2004; 172: 400–408.
Google Scholar | Crossref | Medline | ISI27. Wang, C, Gao, S, Hendrie, HC, et al Antidepressant use in the elderly is associated with an increased risk of dementia. Alzheimer Dis Assoc Disord 2016; 30: 99–104.
Google Scholar | Crossref | Medline28. McIntyre, RS, Lophaven, S, Olsen, CK. A randomized, double-blind, placebo-controlled study of vortioxetine on cognitive function in depressed adults. Int J Neuropsychopharmacol 2014; 17: 1557–1567.
Google Scholar | Crossref | Medline | ISI

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