1. Nikitakis, J, Kowcz, A. Web-based international cosmetic ingredient dictionary and handbook. Accessed: February 19, 2020. Personal Care Products Council; http://webdictionary.personalcarecouncil.org/jsp/Home.jsp
Google Scholar2. Burnett, CL, Boyer, I, Bergfeld, WF, et al. Amended safety assessment of methylisothiazolinone as used in cosmetics. Int J Toxicol. 2019;38(suppl 1):70S–84S.
Google Scholar | SAGE Journals3. Burnett, CL, Bergfeld, WF, Belsito, DV, et al. Final report of the safety assessment of methylisothiazolinone. Int J Toxicol. 2010;29(suppl 3):187S–213S.
Google Scholar | SAGE Journals4. Burnett, CL, Bergfeld, WF, Belsito, DV, et al. Amended safety assessment of methylchloroisothiazolinone and methylisothiazolinone as used in cosmetics. Published 2020. https://www.cir-safety.org/ingredients
Google Scholar5. European Chemicals Agency (ECHA) . 2-methyl-2H-isothiazol-3-one. Published 2020. Accessed January 16, 2020. https://echa.europa.eu/registration-dossier/-/registered-dossier/23868/7/1
Google Scholar6. US Food and Drug Administration (FDA) Center for Food Safety & Applied Nutrition (CFSAN) . Voluntary cosmetic registration program (VCRP) - frequency of use of cosmetic ingredients. College Park, MD Obtained under the Freedom of Information Act from CFSAN; requested as “Use Data Methylisothiazolinone When Used in Cosmetics Without Methylchloroisothiazolinone” October 11, 2019; Received November 11, 2019.
Google Scholar7. Personal Care Products Council . Concentration of use by FDA product category: methylisothiazolinone (used without methylchloroisothiazolinone). Unpublished data submitted by Personal Care Products Council. 2020.
Google Scholar8. Johnsen, MA . The influence of particle size. Spray Technol Market. 2004;14(11):24–27.
Google Scholar9. Rothe, H . Special aspects of cosmetic spray evaluation. Unpublished data presented at the 26 September Expert Panel for Cosmetic Ingredient Safety meeting. 2011.
Google Scholar10. Bremmer, HJ, Homme de Lodder, LCHP, Engelen, JGM. Cosmetics fact sheet: to assess the risks for the consumer. Updated version for ConsExpo 4. Bilthoven, Netherlands 2006 2006. RIVM 320104001/2006. Accessed 8/24/2011. 1–77. http://www.rivm.nl/bibliotheek/rapporten/320104001.pdf
Google Scholar11. Rothe, H, Fautz, R, Gerber, E, et al. Special aspects of cosmetic spray safety evaluations: principles on inhalation risk assessment. Toxicol Lett. 2011;205(2):97–104.
Google Scholar | Crossref | Medline | ISI12. European Union . Regulation (EC) No. 1223/2009 of the European parliament and of the council of 30 November 2009 on cosmetic products. Published 2009. Accessed November 9, 2017. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:342:0059:0209:en:PDF
Google Scholar13. Scientific Committee on Consumer Safety . Opinion on methylisothiazolinone (P94) - submission II, 12 December 2013. Published 2014. SCCS/1521/13. Accessed December 18, 2019. https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_145.pdf
Google Scholar14. US Environmental Protection Agency (EPA) . Registration Review Draft Risk Assessment for 2-Methyl-4-Isothiazolin-3-One (MIT) and 5-Chloro-2-Methyl-4-Isothiazolin-3-One (CMIT). Published April 6, 2020. Accessed May 27, 2020. 94.
Google Scholar15. Anonymous . 13-Week inhalation toxicity study in rats (1984): study summary. Unpublished data submitted on the mixture MCI/MI by the Personal Care Products Council on November 22, 2019.
Google Scholar16. DeKoven, JG, Warshaw, EM, Belsito, DV, et al. North American contact dermatitis group patch test results 2013-2014. Dermatitis. 2017;28(1):33–46.
Google Scholar | Crossref | Medline | ISI17. Warshaw, EM, Aschenbeck, KA, Zug, KA, et al. Wet wipe allergens: retrospective analysis from the North American contact dermatitis group 2011-2014. Dermatitis. 2017;28(1):64–69.
Google Scholar | Crossref | Medline18. Salman, A . Methylchloroisothiazolinone and methylisothiazolinone contact allergy: a retrospective cohort study from a tertiary dermatology clinic in Turkey. Contact Dermatitis. 2019;80(3):193–194.
Google Scholar | Crossref | Medline19. Assier, H, Tetart, F, Avenel-Audran, M, et al. Is a specific eyelid patch test series useful? Results of a French prospective study. Contact Dermatitis. 2018;79(3):157–161.
Google Scholar | Crossref | Medline20. Ljubojevic Hadzavdic, S, Uter, W, Ilijanic Samoscanec, M, Johansen, JD. Methylisothiazolinone contact allergy in Croatia: epidemiology and course of disease following patch testing. Contact Dermatitis. 2018;79(3):162–167.
Google Scholar | Crossref | Medline21. Flury, U, Palmer, A, Nixon, R. The methylisothiazolinone contact allergy epidemic in Australia. Contact Dermatitis. 2018;79(3):189–191.
Google Scholar | Crossref | Medline22. Jacob, SE, McGowan, M, Silverberg, NB, et al. Pediatric contact dermatitis registry data on contact allergy in children with atopic dermatitis. JAMA Dermatol. 2017;153(8):765–770.
Google Scholar | Crossref | Medline23. Bouschon, P, Waton, J, Pereira, B, Schmutz, JL, Le Bouedec, MCF, D’Incan, M. Methylisothiazolinone allergic contact dermatitis: assessment of relapses in 139 patients after avoidance advice. Contact Dermatitis. 2018;80(5):304–310.
Google Scholar | Crossref24. Gallo, R, Signori, A, Gervasio, S, Riva, S, Parodi, A. Methylisothiazolinone contact allergy - are rinse-off cosmetics and household products relevant sources of exposure? Contact Dermatitis. 2016;75(5):319–321.
Google Scholar | Crossref | Medline25. Foley, CC, White, S, Merry, S, et al. Understanding the role of cutaneous allergy testing in anogenital dermatoses: a retrospective evaluation of contact sensitization in anogenital dermatoses. Int J Dermatol. 2019;58(7):806–810.
Google Scholar | Crossref | Medline26. Uter, W, Aalto-Korte, K, Agner, T, et al. The epidemic of methylisothiazolinone contact allergy in Europe: follow-up on changing exposures. J Eur Acad Dermatol Venereol. 2020;34(2):333–339.
Google Scholar | Crossref | Medline27. Deschamps, T, Nosbaum, A, Delcroix, F, Vocanson, M, Berard, F, Nicolas, JF. Long-lasting allergic contact dermatitis to methylisothiazolinone misdiagnosed as atopic dermatitis. Eur J Dermatol. 2019;29(1):100–101.
Google Scholar | Medline28. Gilmore, R, Shan, G, Katta, R.Allergic contact dermatitis to methylisothiazolinone in hair care products: report of a case. Dermatol Online J. 2017;23(8):1–4.
Google Scholar | Crossref29. Mamodaly, M, Dereure, O, Raison-Peyron, N. A new source for isothiazolinone contact allergy in traditional, non-digital photography. Contact Dermatitis. 2019;81(1):76–77.
Google Scholar | Crossref | Medline30. Martinez-Mera, C, Gonzalez, MA, Hospital, M, Turrion-Merion, L. Isothiazolinones in paint as a cause of airborne contact dermatitis in a patient with psoriasis receiving anti-interleukin-17 therapy. Contact Dermatitis. 2019;80(5):328–329.
Google Scholar | Crossref | Medline31. Herry, J, Esquirol, Y, Giordano-Labadie, F. An intriguing occupational atypical dermatitis with respiratory symptoms. Contact Dermatitis. 2016;75(5):322–323.
Google Scholar | Crossref | Medline32. Dahlin, J, Hindsen, M, Persson, C, Isaksson, M. What lash stylists and dermatologists should know! Contact Dermatitis. 2016;75(5):317–319.
Google Scholar | Crossref | Medline33. Bennike, NH, Johansen, JD, Zachariae, C. Please, label the label: a case report of occupational allergic contact dermatitis caused by methylisothiazolinone in adhesive labels. Contact Dermatitis. 2016;75(5):314–315.
Google Scholar | Crossref | Medline34. El-Houri, RB, Christensen, LP, Persson, C, Bruze, M, Andersen, KE. Methylisothiazolinone in a designer spectacle frame - a surprising finding. Contact Dermatitis. 2016;75(5):310–312.
Google Scholar | Crossref | Medline35. Madsen, JT, Andersen, KE, Nielsen, DT, Hvid, L, El-Houri, RB, Christensen, LP. Undisclosed presence of methylisothiazolinone in ‘100% natural’ Konjac sponge. Contact Dermatitis. 2016;75(5):308–309.
Google Scholar | Crossref | Medline36. Dendooven, E, Foubert, K, Naessens, T, Pieters, L, Lambert, J, Aerts, O. Periocular contact allergy from spectacle frames cleaned with methylisothiazolinone-containing household detergents. J Eur Acad Dermatol Venereol. 2019;33(11):e412–e413.
Google Scholar | Crossref | Medline