Staphylococcal scalded skin syndrome (SSSS) is an exfoliative skin condition seen in children and infants and is preceded by a disruption in skin integrity at a distant localized site. The presentation often involves diffuse desquamation of the epidermis, cleavage of the stratum granulosum, and bullae formation due to the circulating exotoxin ( 1 Leung A Barankin B Leong KF. Staphylococcal-scalded skin syndrome: evaluation, diagnosis, and management.

World J Pediatr. 2018; 14: 116-120

). It is a potentially life-threatening condition, and the presentation has a wide differential diagnosis. Prompt treatment is essential for favorable outcomes.