In response to rising nitrate levels in Iowa’s public drinking water, the city of Des Moines built the world’s largest nitrate removal facility. The facility operates when nitrate levels exceed the regulatory threshold of 10 mg/L, incurring costs exceeding $10,000 per day. To evaluate the effect of the nitrate removal facility on birth weight and gestational age, we analyzed publicly available birth certificate microdata (1992-2004). In addition to adjusting for maternal and fraternal sociodemographic factors, our linear regression model included county-year fixed-effects to adjust for annual differences across counties and year-month fixed-effects to account for seasonal variation in birth outcomes. Unbiased identification relied on exogenous geotemporal variation in first-trimester exposure to operation of the nitrate removal facility. Operating the nitrate removal facility was associated with a 0.4-percentage-point increase in the probability of normal birth weight and was associated with a 1.6-percentage-point increase in the probability of a normal term birth. The positive associations were largest among mothers with higher risk of adverse outcomes (smoked during pregnancy, cesarean deliveries, prior preterm births, excessive weight gain, unmarried, unknown father). A post-hoc analysis suggests that this intervention may be cost effective, multiplying public investment by 3.5 dollars in health benefits. As policymakers explore how to address rising nitrate pollution, quantifying the value of nitrate reduction strategies could inform future public health interventions. Although the Des Moines nitrate removal facility appears to serve a crucial public health function and advance health equity, challenges remain for deciding how to pay for this potentially cost-effective intervention.

The authors have declared no competing interest.

This study did not receive any funding.

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