G. Lanzolla, C. Marcocci, M. Marinò, Oxidative stress in graves disease and graves orbitopathy. Eur. Thyroid. J. 9, 40–50 (2020). https://doi.org/10.1159/000509615
Article PubMed PubMed Central CAS Google Scholar
M.L. Tanda, E. Piantanida, L. Liparulo, G. Veronesi, A. Lai, L. Sassi, N. Pariani, D. Gallo, C. Azzolini, M. Ferrario, L. Bartalena, Prevalence and natural history of graves’ orbitopathy in a large series of patients with newly diagnosed graves’ hyperthyroidism seen at a single center. J. Clin. Endocrinol. Metab. 98, 1443–1449 (2013). https://doi.org/10.1210/jc.2012-3873
Article PubMed CAS Google Scholar
L. Bartalena, L. Baldeschi, K. Boboridis, A. Eckstein, G.J. Kahaly, C. Marcocci, P. Perros, M. Salvi, W.M. Wiersinga, The 2016 European thyroid Association/European group on Graves’ orbitopathy guidelines for the management of Graves’ orbitopathy. Eur. Thyroid. J. 5, 9–26 (2016). https://doi.org/10.1159/000443828
Article PubMed PubMed Central CAS Google Scholar
E. Sabini, B. Mazzi, M.A. Profilo, T. Mautone, G. Casini, R. Rocchi, I. Ionni, F. Menconi, M. Leo, M. Nardi, P. Vitti, C. Marcocci, M. Marinò, High serum cholesterol is a novel risk factor for Graves’ orbitopathy: results of a Cross-Sectional Study. Thyroid 28, 386–394 (2018). https://doi.org/10.1089/thy.2017.0430
Article PubMed CAS Google Scholar
A. Naselli, D. Moretti, C. Regalbuto, M.L. Arpi, F. Lo Giudice, F. Frasca, A. Belfiore, R. Le Moli, Evidence that baseline levels of low-density lipoproteins cholesterol affect the clinical response of Graves’ ophthalmopathy to parenteral corticosteroids. Front. Endocrinol. 11, 1–10 (2020). https://doi.org/10.3389/fendo.2020.609895
Y. D, S.R. SK, N.K. R, A. PA, Association between monocyte-to-high-density lipoprotein (HDL) cholesterol ratio and proteinuria in patients with type 2 diabetes mellitus: a Prospective Observational Study. Cureus 15, e45783 (2023). https://doi.org/10.7759/cureus.45783
J. Lin, Z. Li, J. Xu, M. Pan, T. Yin, J. Wang, Q. Sun, W. Zheng, R. Chen, Independent and joint associations of monocyte to high-density lipoprotein-cholesterol ratio and body mass index with cardiorenal syndrome: insights from NHANES 2003–2020. Lipids Health Dis 23, 1–10 (2024). https://doi.org/10.1186/s12944-024-02149-2
A.Y. Alhalwani, S.Y. Hafez, N. Alsubaie, K. Rayani, Y. Alqanawi, Z. Alkhomri, S. Hariri, S. Jambi, Assessment of leukocyte and systemic inflammation index ratios in dyslipidemia patients with dry eye disease: a retrospective case‒control study. Lipids Health Dis 23, 1–9 (2024). https://doi.org/10.1186/s12944-024-02176-z
Y.C. Teh, J.L. Ding, L.G. Ng, S.Z. Chong, Capturing the fantastic voyage of monocytes through time and space. Front. Immunol. 10, 1–9 (2019). https://doi.org/10.3389/fimmu.2019.00834
S. Fang, Y. Lu, Y. Huang, H. Zhou, X. Fan, Mechanisms that underly T cell immunity in Graves’ orbitopathy. Front. Endocrinol. 12, 1–17 (2021). https://doi.org/10.3389/fendo.2021.648732
National Cholesterol Education Program (NCEP) Executive summary of the third report of the national cholesterol education programme. JAMA 285, 2486–2497 (2001). https://doi.org/10.1001/jama.285.19.2486
J.L. Mendoza, K.L. Stafford, Confidence intervals, power calculation, and sample size estimation for the squared multiple correlation coefficient under the fixed and random regression models: a computer program and useful standard tables. Educ. Psychol. Meas. 61, 650–667 (2001)
N.J.D. Nagelkerke, A note on a general definition of the coefficient of determination. Biometrika 78, 691–692 (1991). https://doi.org/10.1093/biomet/78.3.691
J. Yang, L. Zhang, C. Yu, X.-F. Yang, H. Wang, Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases. Biomark. Res. 2, 1 (2014). https://doi.org/10.1126/science.312.5782.1868
Article PubMed PubMed Central Google Scholar
T.J. Smith, TSHR-IGF-IR complex drives orbital fibroblast misbehavior in thyroid eye disease. Curr. Opin. Endocrinol. Diabetes Obes. 31, 177–183 (2024). https://doi.org/10.1097/MED.0000000000000878
Article PubMed CAS Google Scholar
M.S. Draman, M. Ludgate, Thyroid eye disease- an update. Expert. Rev. Ophthalmol. 11, 273–284 (2016). https://doi.org/10.1080/17469899.2016.1202113
K. Shi, H. Li, T. Chang, W. He, Y. Kong, C. Qi, R. Li, H. Huang, Z. Zhu, P. Zheng, Z. Ruan, J. Zhou, F.D. Shi, Q. Liu, Bone marrow hematopoiesis drives multiple sclerosis progression. Cell 185, 2234–2247.e17 (2022). https://doi.org/10.1016/j.cell.2022.05.020
Article PubMed CAS Google Scholar
A. Gulbins, M. Horstmann, S. Keitsch, M. Soddemann, B. Wilker, G.C. Wilson, R. Zeidan, G.D. Hammer, A. Daser, N.E. Bechrakis, G.E. Görtz, A. Eckstein, Potential involvement of the bone marrow in experimental Graves’ disease and thyroid eye disease. Front. Endocrinol. 14, 1–18 (2023). https://doi.org/10.3389/fendo.2023.1252727
G. Lanzolla, G. Vannucchi, I. Ionni, I. Campi, F. Sileo, E. Lazzaroni, M. Marinò, Cholesterol serum levels and use of statins in Graves’ orbitopathy: a new starting point for the therapy. Front. Endocrinol. 10, 1–8 (2020). https://doi.org/10.3389/fendo.2019.00933
P. Duewell, H. Kono, K.J. Rayner, C.M. Sirois, F.G. Bauernfeind, G.S. Abela, L. Franchi, G. Nuñez, T. Espevik, E. Lien, K.A. Fitzgerald, K.L. Rock, G. Vladimer, G. Nunez, M. Schnurr, K.J. Moore, S.D. Wright, V. Hornung, E. Latz, NLRP3 inflamasomes are required for atherogenesis and activated by cholesterol crystals that form early in disease. Nature 464, 1357–1361 (2010). https://doi.org/10.1038/nature08938.NLRP3
Article PubMed PubMed Central CAS Google Scholar
A.R. Tall, M. Westerterp, Inflammasomes, neutrophil extracellular traps, and cholesterol. J. Lipid Res. 60, 721–727 (2019). https://doi.org/10.1194/jlr.S091280
Article PubMed PubMed Central CAS Google Scholar
W.D. Jackson, T.W. Weinrich, K.J. Woollard, Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets. Sci. Rep. 6, 1–12 (2016). https://doi.org/10.1038/srep20038
X. Rao, S. Zhao, Z. Braunstein, H. Mao, M. Razavi, L. Duan, Y. Wei, A.C. Toomey, S. Rajagopalan, J. Zhong, Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways. EBioMedicine 41, 50–61 (2019). https://doi.org/10.1016/j.ebiom.2019.01.065
Article PubMed PubMed Central Google Scholar
J.A.M.J.L. Janssen, T.J. Smith, Lessons learned from targeting IGF-I receptor in thyroid-associated ophthalmopathy. Cells 10, 1–18 (2021). https://doi.org/10.3390/cells10020383
U. Baschant, J. Tuckermann, The role of the glucocorticoid receptor in inflammation and immunity. J. Steroid Biochem. Mol. Biol. 120, 69–75 (2010). https://doi.org/10.1016/j.jsbmb.2010.03.058
Article PubMed CAS Google Scholar
Y. Enuka, M.E. Feldman, A. Chowdhury, S. Srivastava, M. Lindzen, A. Sas-Chen, R. Massart, D. Cheishvili, M.J. Suderman, Y. Zaltsman, C.A. Mazza, K. Shukla, C. Körner, N. Furth, M. Lauriola, M. Oren, S. Wiemann, M. Szyf, Y. Yarden, Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone. Nucleic Acids Res 45, 12681–12699 (2017). https://doi.org/10.1093/nar/gkx865
Article PubMed PubMed Central CAS Google Scholar
R. Le Moli, A. Naselli, G. Costanzo, T. Piticchio, D. Tumino, G. Pellegriti, F. Frasca, A. Belfiore, Determinants of clinical outcome in patients with moderate/severe Graves’ orbitopathy undergoing treatment with parenteral glucocorticoids: a retrospective study. Front. Endocrinol. 15, 1–10 (2024). https://doi.org/10.3389/fendo.2024.1401155
X.Z. Liu, J.M. Wang, Y.X. Ji, D.B. Zhao, Monocyte-to-high-density lipoprotein cholesterol ratio is associated with the presence and size of thyroid nodule irrespective of the gender. Lipids Health Dis 19, 1–7 (2020). https://doi.org/10.1186/s12944-020-1196-z
X.Y. Hu, Y.C. Liang, H.H. Zhang, H.L. Li, D.L. Liu, Association between the systemic immune-inflammation index and thyroid function in U.S. adults. Mediators Inflamm 2023, 5831858 (2023). https://doi.org/10.1155/2023/5831858
Article PubMed PubMed Central Google Scholar
M.H. Lee, Y.H. Chin, C.H. Ng, K.R.Y. Nistala, Z.G.W. Ow, G. Sundar, S.P. Yang, C.M. Khoo, Risk factors of thyroid eye disease. Endocr. Pract. 27, 245–253 (2021).
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