Authors Atif Iqbal 1Department of Oral and Maxillofacial Surgery, Ziauddin College of Dentistry, Ziauddin University, Noor Ul Wahab Department of Research and Methodology, College of Physicians and Surgeons, Pakistan Nabeel Baig College of Physicians & Surgeons Pakistan Afifa Razi Department of Oral Medicine & Diagnosis, Ziauddin, College of Dentistry, Ziauddin University. Komal Shahzad Oral & Maxillofacial Surgery, Ziauddin College of Dentistry, Ziauddin University Dr Hafiz Mujtaba Hussain Oral & Maxillofacial Surgery, Ziauddin College of Dentistry, Ziauddin University DOI: https://doi.org/10.58397/ashkmdc.v29i4.981 Keywords: Dental implants, implantation,, ISQ value, Osseo-integration,, Vitamin D deficiency, Vitamin D supplementation. Abstract

Objective: To assess the impact of vitamin D supplementation on osseointegration success rates in dental implant patients at a tertiary care hospital.
Methods: The randomized control trial included patients aged 18 to 45 years, either gender with Vitamin D insufficiency undergoing dental implant procedures and had vitamin D insufficiency. Exclusion criteria was prior bone regenerative therapy, arthritis, periodontal disease, bleeding disorders, poor oral hygiene, uncontrolled hypertension and diabetes mellitus, severe vitamin D deficiency, chronic renal disease, use of proton pump inhibitors, pregnant women. This was a and patients were enrolled via non probability consecutive sampling. Participants were equally divided into two groups: Group A
received a daily oral intake of 5000 IU Vitamin D3 for 12 weeks, while Group B received a placebo (vitamin E 400mg). Osseo-integration was evaluated at three months using radiographic and clinical assessments with Ostell (ISQ). Additionally, serum Vitamin D levels were measured pre-operatively and post-operatively at 3 months interval post implant placement. Data analysis was performed using SPSS version 23.00.
Results: The median ISQ at three months was notably higher in Group A (Vitamin D supplement) compared to Group B (placebo), with values of 71 vs 65 ISQ (p=0.001). Moreover, the median Vitamin D levels at three months were significantly elevated in Group A compared to Group B (p=0.001). The mean age of the study sample was 33.71±7.84 years. The study found that vitamin D levels were significantly higher in Group A compared with Group B at three months (p=0.001) that suggesting that the supplementation was effective in elevating Vitamin D levels.
Conclusion: The study concludes that Vitamin D supplementation significantly improves osseointegration of dental implants. It emphasizes the importance of targeted vitamin D supplementation in optimizing implant success.

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