Alzheimer’s Association (2023) 2023 Alzheimer’s disease facts and figures. Alzheimer’s Dement 19(4):1598–1695. https://doi.org/10.1002/alz.13016

Article  Google Scholar 

Andermann T, Antonelli A, Barrett RL, Silvestro D (2022) Estimating Alpha, beta, and gamma diversity through deep learning. Front Plant Sci 13:839407. https://doi.org/10.3389/fpls.2022.839407

Article  PubMed  PubMed Central  Google Scholar 

Bao W, He Y, Yu J, Liu M, Yang X, Ta N, Zhang E, Liang C (2022) Regulatory effect of Lactiplantibacillus plantarum 2–33 on intestinal microbiota of mice with antibiotic-associated diarrhea. Front Nutr. https://doi.org/10.3389/fnut.2022.921875

Article  PubMed  PubMed Central  Google Scholar 

Belloni V, Galeazzi A, Bernini G, Mandrioli M, Versace E, Haase A (2018) Evolutionary compromises to metabolic toxins: ammonia and urea tolerance in Drosophila suzukii and Drosophila melanogaster. Physiol Behav 191:146–154. https://doi.org/10.1016/j.physbeh.2018.04.021

Article  PubMed  CAS  Google Scholar 

Brandt SM, Dionne MS, Khush RS, Pham LN, Vigdal TJ, Schneider DS (2004) Secreted bacterial effectors and host-produced eiger/TNF drive death in a Salmonella-infected fruit fly. PLoS Biol 2(12):e418. https://doi.org/10.1371/journal.pbio.0020418

Article  PubMed  PubMed Central  CAS  Google Scholar 

Broderick N, Lemaitre B (2012) Gut-associated microbes of Drosophila melanogaster. Gut Microbes 3(4):307–321. https://doi.org/10.4161/gmic.19896

Article  PubMed  PubMed Central  Google Scholar 

Bronzuoli MR, Iacomino A, Steardo L, Scuderi C (2016) Targeting neuroinflammation in Alzheimer’s disease. J Inflamm Res 9:199–208. https://doi.org/10.2147/JIR.S86958

Article  PubMed  PubMed Central  CAS  Google Scholar 

Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJA, Holmes SP (2016) DADA2: high-resolution sample inference from Illumina amplicon data. Nat Methods 13(7):581. https://doi.org/10.1038/nmeth.3869

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cao YY, Wang L, Ge H, Lu XL, Pei Z, Gu Q, Xu J (2013) Salvianolic acid A, a polyphenolic derivative from Salvia miltiorrhiza bunge, as a multifunctional agent for the treatment of Alzheimer’s disease. Mol Diversity 17(3):515–524. https://doi.org/10.1007/s11030-013-9452-z

Article  CAS  Google Scholar 

Cerqueira GM, Peleg AY (2011) Insights into Acinetobacter baumannii pathogenicity. IUBMB Life 63(12):1055–1060. https://doi.org/10.1002/iub.533

Article  PubMed  CAS  Google Scholar 

Chambers MC, Jacobson E, Khalil S, Lazzaro BP (2019) Consequences of chronic bacterial infection in Drosophila melanogaster. PLoS ONE 14(10):e0224440. https://doi.org/10.1371/journal.pone.0224440

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chandler JA, Lang JM, Bhatnagar S, Eisen JA, Kopp A (2011) Bacterial communities of diverse Drosophila species: ecological context of a host-microbe model system. PLoS Genet 7(9):e1002272. https://doi.org/10.1371/journal.pgen.1002272

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chapman JR, Dowell MA, Chan R, Unckless RL (2020) The genetic basis of natural variation in Drosophila melanogaster immune defense against Enterococcus faecalis. Genes 11(2):234. https://doi.org/10.3390/genes11020234

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cvetković, V. J., Mitrović, T. L., Jovanović, B., Stamenković, S. S., Todorović, M., Đorđević, M., & Radulović, N. (2015). Toxicity of dimethyl sulfoxide against Drosophila melanogaster. Biologica Nyssana, 6(2), Article 2. https://journal.pmf.ni.ac.rs/bionys/index.php/bionys/article/view/156

Douglas GM, Maffei VJ, Zaneveld JR, Yurgel SN, Brown JR, Taylor CM, Huttenhower C, Langille MGI (2020) PICRUSt2 for prediction of metagenome functions. Nat Biotechnol 38(6):685–688. https://doi.org/10.1038/s41587-020-0548-6

Article  PubMed  PubMed Central  CAS  Google Scholar 

Durairajan SSK, Yuan Q, Xie L, Chan W-S, Kum W-F, Koo I, Liu C, Song Y, Huang J-D, Klein WL, Li M (2008) Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty. Neurochem Int 52(4):741–750. https://doi.org/10.1016/j.neuint.2007.09.006

Article  PubMed  CAS  Google Scholar 

Fei Y, Wang S, Yang L, Qiu Y, Li Y, Liu W, Xi T, Fang W, Li Y (2017) Salvia miltiorrhiza Bunge (Danshen) extract attenuates permanent cerebral ischemia through inhibiting platelet activation in rats. J Ethnopharmacol 207:57–66. https://doi.org/10.1016/j.jep.2017.06.023

Article  PubMed  Google Scholar 

Friedland RP, Chapman MR (2017) The role of microbial amyloid in neurodegeneration. PLoS Pathog 13(12):e1006654. https://doi.org/10.1371/journal.ppat.1006654

Article  PubMed  PubMed Central  CAS  Google Scholar 

Galac MR, Lazzaro BP (2011) Comparative pathology of bacteria in the genus Providencia to a natural host Drosophila melanogaster. Microbes Infect 13(7):673–683. https://doi.org/10.1016/j.micinf.2011.02.005

Article  PubMed  PubMed Central  Google Scholar 

Galland L (2014) The gut microbiome and the brain. J Med Food 17(12):1261–1272. https://doi.org/10.1089/jmf.2014.7000

Article  PubMed  PubMed Central  CAS  Google Scholar 

Giannella, R. A. (1996). Salmonella. In S. Baron (Ed.), Medical Microbiology (4th ed.). University of Texas Medical Branch at Galveston. http://www.ncbi.nlm.nih.gov/books/NBK8435/

Gloor GB, Reid G (2016) Compositional analysis: a valid approach to analyze microbiome high-throughput sequencing data. Can J Microbiol 62(8):692–703. https://doi.org/10.1139/cjm-2015-0821

Article  PubMed  CAS  Google Scholar 

Gloor GB, Macklaim JM, Pawlowsky-Glahn V, Egozcue JJ (2017) Microbiome datasets are compositional: and this is not optional. Front Microbiol. https://doi.org/10.3389/fmicb.2017.02224

Article  PubMed  PubMed Central  Google Scholar 

Hansmannel F, Sillaire A, Kamboh MI, Lendon C, Pasquier F, Hannequin D, Laumet G, Mounier A, Ayral A-M, DeKosky ST, Hauw J-J, Berr C, Mann D, Amouyel P, Campion D, Lambert J-C (2010) Is the urea cycle involved in Alzheimer’s Disease? J Alzheimer’s Dis 21(3):1013–1021. https://doi.org/10.3233/JAD-2010-100630

Article  CAS  Google Scholar 

Harding CM, Hennon SW, Feldman MF (2018) Uncovering the mechanisms of Acinetobacter baumannii virulence. Nat Rev Microbiol 16(2):91–102. https://doi.org/10.1038/nrmicro.2017.148

Article  PubMed  CAS  Google Scholar 

He Y, Jia K, Li L, Wang Q, Zhang S, Du J, Du H (2018) Salvianolic acid B attenuates mitochondrial stress against Aβ toxicity in primary cultured mouse neurons. Biochem Biophys Res Commun 498(4):1066–1072. https://doi.org/10.1016/j.bbrc.2018.03.119

Article  PubMed  CAS  Google Scholar 

Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad GG (2013) Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Mol Metab 3(1):42–54. https://doi.org/10.1016/j.molmet.2013.10.003

Article  PubMed  PubMed Central  CAS  Google Scholar 

Huang YS, Zhang JT (1992) Antioxidative effect of three water-soluble components isolated from Salvia miltiorrhiza in vitro. Acta Pharm Sinica 27(2):96–100

CAS  Google Scholar 

Huser A, Rohwedder A, Apostolopoulou AA, Widmann A, Pfitzenmaier JE, Maiolo EM, Selcho M, Pauls D, von Essen A, Gupta T, Sprecher SG, Birman S, Riemensperger T, Stocker RF, Thum AS (2012) The serotonergic central nervous system of the Drosophila larva: anatomy and behavioral function. PLoS ONE 7(10):e47518. https://doi.org/10.1371/journal.pone.0047518

Article  PubMed  PubMed Central  CAS