Transforaminal Steroid Injection After Dorsal Root Ganglion Pulsed Radiofrequency (DRG-PRF): Impact on Pain Intensity and Disability

Breivik H, Eisenberg E, O’Brien T, OPENMinds. The individual and societal burden of chronic pain in Europe: the case for strategic prioritisation and action to improve knowledge and availability of appropriate care. BMC Public Health. 2013;13:1229. https://doi.org/10.1186/1471-2458-13-1229.

Article  PubMed  PubMed Central  Google Scholar 

Knezevic NN, Candido KD, Vlaeyen JWS, Van Zundert J, Cohen SP. Low back pain. Lancet. 2021;398(10294):78–92. https://doi.org/10.1016/S0140-6736(21)00733-9.

Article  PubMed  Google Scholar 

Wuertz K, Haglund L. Inflammatory mediators in intervertebral disk degeneration and discogenic pain. Glob Spine J. 2013;3(3):175–84. https://doi.org/10.1055/s-0033-1347299.

Article  Google Scholar 

Albrecht DS, Ahmed SU, Kettner NW, et al. Neuroinflammation of the spinal cord and nerve roots in chronic radicular pain patients. Pain. 2018;159(5):968–77. https://doi.org/10.1097/j.pain.0000000000001171.

Article  PubMed  PubMed Central  Google Scholar 

Manchikanti L, Knezevic NN, Boswell MV, Kaye AD, Hirsch JA. Epidural injections for lumbar radiculopathy and spinal stenosis: a comparative systematic review and meta-analysis. Pain Physician. 2016;19(3):E365-410.

Article  PubMed  Google Scholar 

Manchikanti L, Benyamin RM, Falco FJE, Kaye AD, Hirsch JA. Do epidural injections provide short- and long-term relief for lumbar disc herniation? A systematic review. Clin Orthop. 2015;473(6):1940–56. https://doi.org/10.1007/s11999-014-3490-4.

Article  PubMed  Google Scholar 

Helm Ii S, Harmon PC, Noe C, et al. Transforaminal epidural steroid injections: a systematic review and meta-analysis of efficacy and safety. Pain Physician. 2021;24(S1):S209–32.

PubMed  Google Scholar 

Olguner SK, Celiktas M, Oktay K, et al. Comparison of 1-year results of single transforaminal epidural steroid injection among patients with different spinal pathologies-related radicular pain. Niger J Clin Pract. 2020;23(6):835–41. https://doi.org/10.4103/njcp.njcp_24_19.

Article  CAS  PubMed  Google Scholar 

Oliveira CB, Maher CG, Ferreira ML, et al. Epidural corticosteroid injections for lumbosacral radicular pain. Cochrane Database Syst Rev. 2020;4(4):CD013577. https://doi.org/10.1002/14651858.CD013577.

Article  PubMed  Google Scholar 

Napoli A, Alfieri G, Scipione R, Andrani F, Leonardi A, Catalano C. Pulsed radiofrequency for low-back pain and sciatica. Expert Rev Med Devices. 2020;17(2):83–6. https://doi.org/10.1080/17434440.2020.1719828.

Article  CAS  PubMed  Google Scholar 

Byrd D, Mackey S. Pulsed radiofrequency for chronic pain. Curr Pain Headache Rep. 2008;12(1):37–41. https://doi.org/10.1007/s11916-008-0008-3.

Article  PubMed  PubMed Central  Google Scholar 

Abejón D, Garcia-del-Valle S, Fuentes ML, Gómez-Arnau JI, Reig E, van Zundert J. Pulsed radiofrequency in lumbar radicular pain: clinical effects in various etiological groups. Pain Pract. 2007;7(1):21–6. https://doi.org/10.1111/j.1533-2500.2007.00105.x.

Article  PubMed  Google Scholar 

Chao SC, Lee HT, Kao TH, et al. Percutaneous pulsed radiofrequency in the treatment of cervical and lumbar radicular pain. Surg Neurol. 2008;70(1):59–65. https://doi.org/10.1016/j.surneu.2007.05.046. (Discussion: 65).

Article  PubMed  Google Scholar 

Koh W, Choi SS, Karm MH, et al. Treatment of chronic lumbosacral radicular pain using adjuvant pulsed radiofrequency: a randomized controlled study. Pain Med. 2015;16(3):432–41. https://doi.org/10.1111/pme.12624.

Article  PubMed  Google Scholar 

Nagda JV, Davis CW, Bajwa ZH, Simopoulos TT. Retrospective review of the efficacy and safety of repeated pulsed and continuous radiofrequency lesioning of the dorsal root ganglion/segmental nerve for lumbar radicular pain. Pain Physician. 2011;14(4):371–6.

Article  PubMed  Google Scholar 

Shanthanna H, Chan P, McChesney J, Paul J, Thabane L. Pulsed radiofrequency treatment of the lumbar dorsal root ganglion in patients with chronic lumbar radicular pain: a randomized, placebo-controlled pilot study. J Pain Res. 2014. https://doi.org/10.2147/JPR.S55749.

Article  PubMed  PubMed Central  Google Scholar 

Van Boxem K, de Meij N, Kessels A, Van Kleef M, Van Zundert J. Pulsed radiofrequency for chronic intractable lumbosacral radicular pain: a six-month cohort study. Pain Med. 2015;16(6):1155–62. https://doi.org/10.1111/pme.12670.

Article  PubMed  Google Scholar 

Chua NHL, Vissers KC, Sluijter ME. Pulsed radiofrequency treatment in interventional pain management: mechanisms and potential indications—a review. Acta Neurochir (Wien). 2011;153(4):763–71. https://doi.org/10.1007/s00701-010-0881-5.

Article  PubMed  Google Scholar 

Podhajsky RJ, Sekiguchi Y, Kikuchi S, Myers RR. The histologic effects of pulsed and continuous radiofrequency lesions at 42 °C to rat dorsal root ganglion and sciatic nerve. Spine. 2005;30(9):1008–13. https://doi.org/10.1097/01.brs.0000161005.31398.58.

Article  PubMed  Google Scholar 

Park D, Chang MC. The mechanism of action of pulsed radiofrequency in reducing pain: a narrative review. J Yeungnam Med Sci. 2022;39(3):200–5. https://doi.org/10.12701/jyms.2022.00101.

Article  PubMed  PubMed Central  Google Scholar 

Cho HK, Kang JH, Kim SY, et al. Changes in neuroglial activity in multiple spinal segments after caudal epidural pulsed radiofrequency in a rat model of lumbar disc herniation. Pain Physician. 2016;19(8):E1197–209.

PubMed  Google Scholar 

Moffett J, Fray LM, Kubat NJ. Activation of endogenous opioid gene expression in human keratinocytes and fibroblasts by pulsed radiofrequency energy fields. J Pain Res. 2012;5:347–57. https://doi.org/10.2147/JPR.S35076.

Article  PubMed  PubMed Central  Google Scholar 

Hagiwara S, Iwasaka H, Takeshima N, Noguchi T. Mechanisms of analgesic action of pulsed radiofrequency on adjuvant-induced pain in the rat: roles of descending adrenergic and serotonergic systems. Eur J Pain. 2009;13(3):249–52. https://doi.org/10.1016/j.ejpain.2008.04.013.

Article  CAS  PubMed  Google Scholar 

Erdine S, Bilir A, Cosman ER, Cosman ER. Ultrastructural changes in axons following exposure to pulsed radiofrequency fields. Pain Pract. 2009;9(6):407–17. https://doi.org/10.1111/j.1533-2500.2009.00317.x.

Article  PubMed  Google Scholar 

Vallejo R, Tilley DM, Williams J, Labak S, Aliaga L, Benyamin RM. Pulsed radiofrequency modulates pain regulatory gene expression along the nociceptive pathway. Pain Physician. 2013;16(5):E601-613.

Article  PubMed  Google Scholar 

Jiang R, Li P, Yao YX, et al. Pulsed radiofrequency to the dorsal root ganglion or the sciatic nerve reduces neuropathic pain behavior, decreases peripheral pro-inflammatory cytokines and spinal β-catenin in chronic constriction injury rats. Reg Anesth Pain Med. 2019. https://doi.org/10.1136/rapm-2018-100032.

Article  PubMed  Google Scholar 

Arons M, Pilmane M, Bhaskar A, Kopsky DJ, Romanenko V, Rohof O. Pulsed radiofrequency increases nestin and matrix metalloproteinase-2 expression in porcine lumbar dorsal root ganglion. Anesthesiol Pain Med. 2022;12(1): e110531. https://doi.org/10.5812/aapm.110531.

Article  Google Scholar 

Hong LW, Chen KT. A real-world evidence of a consecutive treatment of 42 spine-related pain using dorsal root ganglion-pulsed radiofrequency (DRG-PRF). Clin Neurol Neurosurg. 2020;197:106186. https://doi.org/10.1016/j.clineuro.2020.106186.

Article  PubMed  Google Scholar 

Kim WH, Sim WS, Shin BS, et al. Effects of two different doses of epidural steroid on blood glucose levels and pain control in patients with diabetes mellitus. Pain Physician. 2013;16(6):557–68.

PubMed  Google Scholar 

Botwin KP, Gruber RD, Bouchlas CG, Torres-Ramos FM, Freeman TL, Slaten WK. Complications of fluoroscopically guided transforaminal lumbar epidural injections. Arch Phys Med Rehabil. 2000;81(8):1045–50. https://doi.org/10.1053/apmr.2000.7166.

Article  CAS  PubMed  Google Scholar 

Baker R, Dreyfuss P, Mercer S, Bogduk N. Cervical transforaminal injection of corticosteroids into a radicular artery: a possible mechanism for spinal cord injury. Pain. 2003;103(1–2):211–5. https://doi.org/10.1016/s0304-3959(02)00343-3.

Article  PubMed  Google Scholar 

Moon HS, Kim YD, Song BH, Cha YD, Song JH

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