Amiodarone extraction by continuous renal replacement therapy: results from an ex vivo study

Podrid PJ. Amiodarone: reevaluation of an old drug. Ann Intern Med. 1995;122:689–700.

Article  PubMed  CAS  Google Scholar 

Zipes DP, Prystowsky EN, Heger JJ. Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects. J Am Coll Cardiol. 1984;3:1059–71.

Article  PubMed  CAS  Google Scholar 

Freedman M, Somberg J. Pharmacology and pharmacokinetics of amiodarone. J Clin Pharmacol. 1991;31:1061–9.

Article  PubMed  CAS  Google Scholar 

Desai AD, Chun S, Sung RJ. The role of intravenous amiodarone in the management of cardiac arrhythmias. Ann Intern Med. 1997;127:294–303.

Article  PubMed  CAS  Google Scholar 

Rotmensch HH, Belhassen B, Swanson BN, Shoshani D, Spielman SR, Greenspon AJ, et al. Steady-state serum amiodarone concentrations: relationships with antiarrhythmic efficacy and toxicity. Ann Intern Med. 1984;101:462–9.

Article  PubMed  CAS  Google Scholar 

McDonald MG, Au NT, Rettie AE. P450-based drug-drug interactions of amiodarone and its metabolites: diversity of inhibitory mechanisms. Drug Metab Dispos. 2015;43:1661–9.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Korth-Bradley JM, Rose GM, De Vane PJ, Peters J, Chiang ST. Population pharmacokinetics of intravenous amiodarone in patients with refractory ventricular tachycardia/fibrillation. J Clin Pharmacol. 1996;36:715–9.

Article  PubMed  CAS  Google Scholar 

Shekar K, Roberts JA, Mcdonald CI, Ghassabian S, Anstey C, Wallis SC, et al. Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study. Crit Care. 2015;19:1–8.

Article  Google Scholar 

Wildschut ED, Ahsman MJ, Allegaert K, Mathot RAA, Tibboel D. Determinants of drug absorption in different ECMO circuits. Intensive Care Med. 2010;36:2109–16.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Pea F, Viale P, Pavan F, Furlanut M. Pharmacokinetic considerations for antimicrobial therapy in patients receiving renal replacement therapy. Clin Pharmacokinet. 2007;46:997–1038.

Article  PubMed  CAS  Google Scholar 

Latini R, Tognoni G, Kates RE. Clinical pharmacokinetics of amiodarone. Clin Pharmacokinet. 1984;9:136–56.

Article  PubMed  CAS  Google Scholar 

Chaijamorn W, Shaw AR, Lewis SJ, Mueller BA. Ex vivo ceftolozane/tazobactam clearance during continuous renal replacement therapy. Blood Purif. 2017;44:16–23.

Article  PubMed  CAS  Google Scholar 

Choi G, Gomersall CD, Lipman J, Wong A, Joynt GM, Leung P, et al. The effect of adsorption, filter material and point of dilution on antibiotic elimination by haemofiltration an in vitro study of levofloxacin. Int J Antimicrob Agents. 2004;24:468–72.

PubMed  CAS  Google Scholar 

Hospira, Inc., Lake Forest, IL [Internet]. 1995. Amiodarone HCl injection for intravenous use [package insert]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/075955s015lbl.pdf

Lehnert A, Foissac F, Bouazza N, Urien S, Oualha M, Renolleau S, et al. Amiodarone/N-desethylamiodarone population pharmacokinetics in paediatric patients. Br J Clin Pharmacol. 2022;88:5369–77.

Article  PubMed  CAS  Google Scholar 

Juenke JEM, Brown PI, McMillin GA, Urry FM. A rapid procedure for the monitoring of amiodarone and N-desethylamiodarone by HPLC-UV detection. J Anal Toxicol. 2004;28:63–6.

Article  PubMed  CAS  Google Scholar 

Beal S. Ways to fit a PK model with some data below the quantification limit. J Pharmacokinet Pharmacodyn. 2001;28:481–504.

Article  PubMed  CAS  Google Scholar 

Harris L, Hind CRK, Mckenna WJ, Savage C, Krikler SJ, Storeyt GCA, et al. Renal elimination of amiodarone and its desethyl metabolite. Postgrad Med J. 1983;59:440–2.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bonati M, Galletti F, Volpi A, Cumetti C, Rumolo R, Bassini O, et al. Amiodarone in patients on long-term dialysis. N Engl J Med. 1983;308:906.

Article  PubMed  CAS  Google Scholar 

McDaniel CG, Honeycutt CC, Watt KM. Amiodarone extraction by the extracorporeal membrane oxygenation circuit. J Extra Corpor Technol. 2021;53:68–74.

Article  PubMed  PubMed Central  Google Scholar 

Lescroart M, Pressiat C, Péquignot B, Tran N, Hébert JL, Alsagheer N, et al. Impaired pharmacokinetics of amiodarone under veno-venous extracorporeal membrane oxygenation: from bench to bedside. Pharmaceutics. 2022;14:1–15.

Article  Google Scholar 

Onichimowski D, Ziółkowski H, Nosek K, Jaroszewski J, Rypulak E, Czuczwar M. Comparison of adsorption of selected antibiotics on the filters in continuous renal replacement therapy circuits: in vitro studies. J Artif Organs. 2020;23:163–70.

Article  PubMed  CAS  Google Scholar 

Onichimowski D, Nosek K, Ziółkowski H, Jaroszewski J, Pawlos A, Czuczwar M. Adsorption of vancomycin, gentamycin, ciprofloxacin and tygecycline on the filters in continuous renal replacement therapy circuits: in full blood in vitro study. J Artif Organs. 2020;24:65–73.

Article  PubMed  PubMed Central  Google Scholar 

Troyanov S, Cardinal J, Geadah D, Parent D, Courteau S, Caron S, et al. Solute clearances during continuous venovenous haemofiltration at various ultrafiltration flow rates using multiflow-100 and HF1000 filters. Nephrol Dial Transplant. 2003;18:961–6.

Article  PubMed  Google Scholar 

Jamal JA, Mueller BA, Choi GYS, Lipman J, Roberts JA. How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy? Diagn Microbiol Infect Dis. 2015;82:92–103.

Article  PubMed  CAS  Google Scholar 

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