Therapeutic Plasma Exchange for a Critically Ill Late Preterm Infant with Multisystem Inflammatory Syndrome of Children: A Case Report and Review of the Literature

J Pediatr Infect Dis
DOI: 10.1055/s-0044-1789607

1 Department of Neonatology, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, University of Health Sciences, Istanbul, Türkiye

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1 Department of Neonatology, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, University of Health Sciences, Istanbul, Türkiye

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1 Department of Neonatology, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, University of Health Sciences, Istanbul, Türkiye

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2 Pediatrics, Pediatric Intensive Care Unit Department, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, University of Health Sciences, Istanbul, Türkiye

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3 Pediatric Emergency Department, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, University of Health Sciences, Istanbul, Türkiye

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1 Department of Neonatology, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, University of Health Sciences, Istanbul, Türkiye

› Author Affiliations Funding This research did not receive any grant from the public, commercial, or not-for-profit sector funding agencies.
› Further Information Also available at

Buy Article Permissions and Reprints Abstract

Multisystem inflammatory syndrome of children (MIS-C) is a clinical picture that entered the medical nomenclature after the coronavirus disease 2019 pandemic. Although it primarily affects older children, there have been a limited number of cases reported during the neonatal period. Herein we present a patient, a late preterm infant, with severe MIS-C-related cerebral sinus venous thrombosis who was successfully treated with therapeutic plasma exchange. Practitioners can consider therapeutic plasma exchange as a safe and effective option for the treatment of critically ill MIS-C cases.

Keywords COVID-19 - MIS-C - newborn - therapeutic plasma exchange Ethics Approval

Institutional Review Board approval was received from local Ethics Committee of our university.

Informed Consent

Informed consent was obtained from the parents prior to participation in the study.

Data Availability

All data of the patient are stored in the data recording system of our hospital.

Publication History

Received: 18 January 2024

Accepted: 06 August 2024

Article published online:
29 August 2024

© 2024. Thieme. All rights reserved.

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