The authors wish to thank the patients and their family for their participation in this study. The authors thank Mme Nathalie Le Metayer for technical help and the Genobiomics platform for NGS facilities. Y.J.C. acknowledges the European Research Council (786142 E-T1IFNs), a UK Medical Research Council Human Genetics Unit core grant (MC_UU_00035/11), and a state subsidy from the Agence Nationale de la Recherche (France) under the ‘Investissements d’avenir’ program bearing the reference ANR-10-IAHU-01.

Contributor Information

For the SAVI group:

7Paediatric Radiology Department, Hôpital Necker-Enfants Malades, AP-HP.Centre Université de Paris, Paris, France.

8MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom.

9Paediatric Pulmonology Department, Hôpital Necker-Enfants Malades, AP-HP.Centre Université de Paris, Paris, France.

10INEM, INSERM U1151, Paris, France.

11Laboratory of Immunogenetics of Pediatric Autoimmunity, Imagine Institute, INSERM UMR 1163, Paris, France.

12Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PT, United Kingdom.

13Dermatology Department, Hôpital Necker-Enfants Malades, AP-HP.Centre Université de Paris, Paris, France.