Buratta, S., Tancini, B., Sagini, K., Delo, F., Chiaradia, E., Urbanelli, L., & Emiliani, C. (2020). Lysosomal exocytosis, exosome release and secretory autophagy: The autophagic-and endo-lysosomal systems go extracellular. International journal of molecular sciences., 21(7), 2576.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi, R., Wang, P. Y., Li, X. Y., Chen, J. X., Li, Y., Zhang, X. Z., Zhang, C. G., Jiang, T., Li, W. B., Ding, W., & Cheng, S. J. (2015). Exosomal levels of miRNA-21 from cerebrospinal fluids associated with poor prognosis and tumor recurrence of glioma patients. Oncotarget, 6(29), 26971.

Article  PubMed  PubMed Central  Google Scholar 

Pisitkun, T., Shen, R. F., & Knepper, M. A. (2004). Identification and proteomic profiling of exosomes in human urine. Proceedings of the National Academy of Sciences., 101(36), 13368–13373.

Article  CAS  Google Scholar 

Zlotogorski-Hurvitz, A., Dayan, D., Chaushu, G., Korvala, J., Salo, T., Sormunen, R., & Vered, M. (2015). Human saliva-derived exosomes: Comparing methods of isolation. Journal of Histochemistry & Cytochemistry., 63(3), 181–189.

Article  CAS  Google Scholar 

Li, Z., Wang, Y., Xiao, K., Xiang, S., Li, Z., & Weng, X. (2018). Emerging role of exosomes in the joint diseases. Cellular Physiology and Biochemistry., 47(5), 2008–2017.

Article  CAS  PubMed  Google Scholar 

Liu, S. L., Sun, P., Li, Y., Liu, S. S., & Lu, Y. (2019). Exosomes as critical mediators of cell-to-cell communication in cancer pathogenesis and their potential clinical application. Translational Cancer Research., 8(1), 298.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mosquera-Heredia, M. I., Morales, L. C., Vidal, O. M., Barcelo, E., Silvera-Redondo, C., Vélez, J. I., & Garavito-Galofre, P. (2021). Exosomes: Potential disease biomarkers and new therapeutic targets. Biomedicines., 9(8), 1061.

Article  PubMed  PubMed Central  Google Scholar 

Hawker, G. A., & King, L. K. (2022). The burden of osteoarthritis in older adults. Clinics in Geriatric Medicine., 38(2), 181–192.

Article  PubMed  Google Scholar 

He, Y., Li, Z., Alexander, P. G., Ocasio-Nieves, B. D., Yocum, L., Lin, H., & Tuan, R. S. (2020). Pathogenesis of osteoarthritis: Risk factors, regulatory pathways in chondrocytes, and experimental models. Biology., 9(8), 194.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Uivaraseanu, B., Vesa, C. M., Tit, D. M., Abid, A., Maghiar, O., Maghiar, T. A., Hozan, C., Nechifor, A. C., Behl, T., Patrascu, J. M., & Bungau, S. (2022). Therapeutic approaches in the management of knee osteoarthritis. Experimental and Therapeutic Medicine., 23(5), 1–6.

Article  Google Scholar 

Fan, W. J., Liu, D., Pan, L. Y., Wang, W. Y., Ding, Y. L., Zhang, Y. Y., Ye, R. X., Zhou, Y., An, S. B., & Xiao, W. F. (2022). Exosomes in osteoarthritis: Updated insights on pathogenesis, diagnosis, and treatment. Frontiers in Cell and Developmental Biology., 26(10), 949690.

Article  Google Scholar 

Pan, B. T., & Johnstone, R. M. (1983). Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor. Cell, 33(3), 967–978.

Article  CAS  PubMed  Google Scholar 

Wolf, P. (1967). The nature and significance of platelet products in human plasma. British Journal of Haematology., 13(3), 269–288.

Article  CAS  PubMed  Google Scholar 

Johnstone, R. M., Adam, M., Hammond, J. R., Orr, L., & Turbide, C. (1987). Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). Journal of Biological Chemistry., 262(19), 9412–9420.

Article  CAS  PubMed  Google Scholar 

Valenzuela, M. M., Ferguson Bennit, H. R., Gonda, A., Diaz Osterman, C. J., Hibma, A., Khan, S., & Wall, N. R. (2015). Exosomes secreted from human cancer cell lines contain inhibitors of apoptosis (IAP). Cancer Microenvironment., 8, 65–73.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Williams, R. L., & Urbé, S. (2007). The emerging shape of the ESCRT machinery. Nature reviews Molecular cell biology., 8(5), 355–368.

Article  CAS  PubMed  Google Scholar 

Yue, B., Yang, H., Wang, J., Ru, W., Wu, J., Huang, Y., Lan, X., Lei, C., & Chen, H. (2020). Exosome biogenesis, secretion and function of exosomal miRNAs in skeletal muscle myogenesis. Cell Proliferation., 53(7), e12857.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kalluri, R., & LeBleu, V. S. (2020). The biology, function, and biomedical applications of exosomes. Science, 367(6478), eaau6977.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang, Y., Bi, J., Huang, J., Tang, Y., Du, S., & Li, P. (2020). Exosome: A review of its classification, isolation techniques, storage, diagnostic and targeted therapy applications. International Journal of Nanomedicine., 22, 6917–6934.

Article  Google Scholar 

Shu, S. L., Yang, Y., Allen, C. L., Hurley, E., Tung, K. H., Minderman, H., Wu, Y., & Ernstoff, M. S. (2020). Purity and yield of melanoma exosomes are dependent on isolation method. Journal of Extracellular Vesicles., 9(1), 1692401.

Article  PubMed  Google Scholar 

Patel, G. K., Khan, M. A., Zubair, H., Srivastava, S. K., Khushman, M. D., Singh, S., & Singh, A. P. (2019). Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications. Scientific Reports., 9(1), 5335.

Article  PubMed  PubMed Central  Google Scholar 

Tang, Y. T., Huang, Y. Y., Zheng, L., Qin, S. H., Xu, X. P., An, T. X., Xu, Y., Wu, Y. S., Hu, X. M., Ping, B. H., & Wang, Q. (2017). Comparison of isolation methods of exosomes and exosomal RNA from cell culture medium and serum. International Journal of Molecular Medicine., 40(3), 834–844.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Diaz, G., Bridges, C., Lucas, M., Cheng, Y., Schorey, J. S., Dobos, K. M., & Kruh-Garcia, N. A. (2018). Protein digestion, ultrafiltration, and size exclusion chromatography to optimize the isolation of exosomes from human blood plasma and serum. JoVE (Journal of Visualized Experiments)., 134, e57467.

Google Scholar 

Yu, L. L., Zhu, J., Liu, J. X., Jiang, F., Ni, W. K., Qu, L. S., Ni, R. Z., Lu, C. H., & Xiao, M. B. (2018). A comparison of traditional and novel methods for the separation of exosomes from human samples. BioMed Research International., 26, 2018.

Google Scholar 

Zeringer, E., Barta, T., Li, M., & Vlassov, A. V. (2015). Strategies for isolation of exosomes. Cold Spring Harbor Protocols., 2015(4), 074476.

Article  Google Scholar 

Momen-Heravi, F., Balaj, L., Alian, S., Trachtenberg, A. J., & Kuo, W. P. (2012). Impact of biofluid viscosity on size and sedimentation efficiency of the isolated microvesicles. Frontiers in Physiology., 29(3), 26975.

Google Scholar 

Sall, I. M., & Flaviu, T. A. (2023). Plant and mammalian-derived extracellular vesicles: a new therapeutic approach for the future. Frontiers in Bioengineering and Biotechnology. https://doi.org/10.3389/fbioe.2023.1215650

Article  PubMed  PubMed Central  Google Scholar 

Uddin, M. J., Mohite, P., Munde, S., Ade, N., Oladosu, T. A., Chidrawar, V. R., Patel, R., Bhattacharya, S., Paliwal, H., & Singh, S. (2024). Extracellular vesicles: The future of therapeutics and drug delivery systems. Intelligent Pharmacy. https://doi.org/10.1016/j.ipha.2024.02.004

Article  Google Scholar 

Sharma, P., Ludwig, S., Muller, L., Hong, C. S., Kirkwood, J. M., Ferrone, S., & Whiteside, T. L. (2018). Immunoaffinity-based isolation of melanoma cell-derived exosomes from plasma of patients with melanoma. Journal of Extracellular Vesicles., 7(1), 1435138.

Article  PubMed  PubMed Central  Google Scholar 

Rider, M. A., Hurwitz, S. N., & Meckes, D. G. (2016). ExtraPEG: A polyethylene glycol-based method for enrichment of extracellular vesicles. Scientific Reports., 6(1), 1–4.

Article  Google Scholar 

Yang, D., Zhang, W., Zhang, H., Zhang, F., Chen, L., Ma, L., Larcher, L. M., Chen, S., Liu, N., Zhao, Q., & Tran, P. H. (2020). Progress, opportunity, and perspective on exosome isolation-efforts for efficient exosome-based theranostics. Theranostics., 10(8), 3684.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Slyusarenko, M., Nikiforova, N., Sidina, E., Nazarova, I., Egorov, V., Garmay, Y., Merdalimova, A., Yevlampieva, N., Gorin, D., & Malek, A. (2021). Formation and evaluation of a two-phase polymer system in human plasma as a method for extracellular nanovesicle isolation. Polymers, 13(3), 458.