Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE (2014) Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma, vol 344. Science, New York, N.Y., pp 1396–1401
Wan RJ, Peng W, Xia QX, Zhou HH, Mao XY (2021) Ferroptosis-related gene signature predicts prognosis and immunotherapy in glioma. CNS Neurosci Ther 27:973–986
Article CAS PubMed PubMed Central Google Scholar
Parmigiani E, Ivanek R, Rolando C, Hafen K, Turchinovich G, Lehmann FM, Gerber A, Brkic S, Frank S, Meyer SC, Wakimoto H, Günel M, Louvi A, Mariani L, Finke D, Holländer G, Hutter G, Tussiwand R, Taylor V, Giachino C (2022) Interferon-γ resistance and immune evasion in glioma develop via notch-regulated co-evolution of malignant and immune cells. Dev Cell 57:1847–1865e9
Article CAS PubMed Google Scholar
Szklarczyk D, Kirsch R, Koutrouli M, Nastou K, Mehryary F, Hachilif R, Gable AL, Fang T, Doncheva NT, Pyysalo S, Bork P, Jensen LJ, von Mering C (2023) The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest. Nucleic Acids Res 51:D638–d646
Article CAS PubMed Google Scholar
Han W, Li C, Wang Y, Huo B, Li W, Shi W (2023) Heme Metabolism-related gene TENT5C is a prognostic marker and investigating its immunological role in Colon cancer. Pharmacogenomics Personalized Med 16:1127–1143
Geeleher P, Cox NJ, Huang RS (2014) Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines. Genome Biol 15:R47
Article PubMed PubMed Central Google Scholar
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR (2006) The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease, vol 313. Science, pp 1929–1935. (New York, N.Y.)
Yang C, Zhang H, Chen M, Wang S, Qian R, Zhang L, Huang X, Wang J, Liu Z, Qin W, Wang C, Hang H, Wang H (2022) A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer. eLife 11
Takano S, Ishikawa E, Matsuda M, Yamamoto T, Matsumura A (2014) Interferon-β inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10. Int J Oncol 45:1837–1846
Article CAS PubMed PubMed Central Google Scholar
Zainulabadeen A, Yao P, Zare H (2017) Underexpression of specific Interferon genes is Associated with poor prognosis of Melanoma. PLoS ONE 12:e0170025
Article PubMed PubMed Central Google Scholar
Han XX, Jin S, Yu LM, Wang M, Hu XY, Hu DY, Ren J, Zhang MH, Huang W, Deng JJ, Chen QQ, Gao Z, He H, Cai C (2022) Interferon-beta inhibits human glioma stem cell growth by modulating immune response and cell cycle related signaling pathways. Cell Regeneration (London England) 11:23
Article CAS PubMed Google Scholar
Hoekstra ME, Bornes L, Dijkgraaf FE, Philips D, Pardieck IN, Toebes M, Thommen DS, van Rheenen J, Schumacher TNM (2020) Long-distance modulation of bystander tumor cells by CD8(+) T cell-secreted IFNγ. Nat cancer 1:291–301
Article CAS PubMed PubMed Central Google Scholar
Ding H, Wang G, Yu Z, Sun H, Wang L (2022) Role of interferon-gamma (IFN-γ) and IFN-γ receptor 1/2 (IFNγR1/2) in regulation of immunity, infection, and cancer development: IFN-γ-dependent or independent pathway. Biomed Pharmacotherapy = Biomedecine Pharmacotherapie 155:113683
Frescaline G, Bouderlique T, Huynh MB, Papy-Garcia D, Courty J, Albanese P (2012) Glycosaminoglycans mimetics potentiate the clonogenicity, proliferation, migration and differentiation properties of rat mesenchymal stem cells. Stem cell Res 8:180–192
Article CAS PubMed Google Scholar
Aguiar CB, Lobão-Soares B, Alvarez-Silva M, Trentin AG (2005) Glycosaminoglycans modulate C6 glioma cell adhesion to extracellular matrix components and alter cell proliferation and cell migration. BMC Cell Biol 6:31
Wang L (2016) Mitochondrial purine and pyrimidine metabolism and beyond. Nucleosides Nucleotides Nucleic Acids 35:578–594
Article CAS PubMed Google Scholar
Basappa KS, Rangappa, Sugahara K (2014) Roles of glycosaminoglycans and glycanmimetics in tumor progression and metastasis. Glycoconj J 31:461–467
Article CAS PubMed Google Scholar
Nakamizo A, Miyamatsu Y, Hirose H, Amano T, Matsuo S, Fujiwara M, Shimamura T, Yoshimoto K (2022) Metabolic remodeling of pyrimidine synthesis pathway and serine synthesis pathway in human glioblastoma. Sci Rep 12:16277
Article CAS PubMed PubMed Central Google Scholar
Wang LM, Englander ZK, Miller ML, Bruce JN (2023) Malignant Glioma Adv Experimental Med Biology 1405:1–30
Davis ME (2018) Epidemiology and overview of Gliomas. Semin Oncol Nurs 34:420–429
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987–996
Article CAS PubMed Google Scholar
Ghotme KA, Barreto GE, Echeverria V, Gonzalez J, Bustos RH, Sanchez M, Leszek J, Yarla NS, Gomez RM, Tarasov VV, Ashraf GM, Aliev G (2017) Gliomas: New perspectives in diagnosis, treatment and prognosis. Curr Top Med Chem 17:1438–1447
Article CAS PubMed Google Scholar
Yu R, Zhu B, Chen D (2022) Type I interferon-mediated tumor immunity and its role in immunotherapy. Cell Mol Life Sci 79:191
Article CAS PubMed PubMed Central Google Scholar
Lukhele S, Rabbo DA, Guo M, Shen J, Elsaesser HJ, Quevedo R, Carew M, Gadalla R, Snell LM, Mahesh L, Ciudad MT, Snow BE, You-Ten A, Haight J, Wakeham A, Ohashi PS, Mak TW, Cui W, McGaha TL, Brooks DG (2022) The transcription factor IRF2 drives interferon-mediated CD8(+) T cell exhaustion to restrict anti-tumor immunity. Immunity 55:2369–2385e10
Article CAS PubMed PubMed Central Google Scholar
Platanias LC (2005) Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 5:375–386
Article CAS PubMed Google Scholar
Lasfar A, Abushahba W, Balan M, Cohen-Solal KA (2011) Interferon lambda: a new sword in cancer immunotherapy. Clin Dev Immunol 2011:349575
Article PubMed PubMed Central Google Scholar
Tarassishin L, Lee SC (2013) Interferon regulatory factor 3 alters glioma inflammatory and invasive properties. J Neurooncol 113:185–194
Article CAS PubMed Google Scholar
Garrison JI, Berens ME, Shapiro JR, Treasurywala S, Floyd-Smith G (1996) Interferon-beta inhibits proliferation and progression through S phase of the cell cycle in five glioma cell lines. J Neurooncol 30:213–223
Article CAS PubMed Google Scholar
Jin X, Kim SH, Jeon HM, Beck S, Sohn YW, Yin J, Kim JK, Lim YC, Lee JH, Kim SH, Kang SH, Pian X, Song MS, Park JB, Chae YS, Chung YG, Lee SH, Choi YJ, Nam DH, Choi YK, Kim H (2012) Interferon regulatory factor 7 regulates glioma stem cells via interleukin-6 and notch signalling. Brain 135:1055–1069
Seliger B, Maeurer MJ, Ferrone S (2000) Antigen-processing machinery breakdown and tumor growth. Immunol Today 21:455–464
Article CAS PubMed Google Scholar
Yang I, Kremen TJ, Giovannone AJ, Paik E, Odesa SK, Prins RM, Liau LM (2004) Modulation of major histocompatibility complex class I molecules and major histocompatibility complex-bound immunogenic peptides induced by interferon-alpha and interferon-gamma treatment of human glioblastoma multiforme. J Neurosurg 100:310–319
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