Discrimination of pediatric cryptogenic multifocal ulcerous stenosing enteritis from small bowel Crohn’s disease and gastrointestinal tuberculosis: A retrospective study (with videos)

Perlemuter G, Guillevin L, Legman P, Weiss L, Couturier D, Chaussade S. Cryptogenetic multifocal ulcerous stenosing enteritis: an atypical type of vasculitis or a disease mimicking vasculitis. Gut. 2001;48:333–8. https://doi.org/10.1136/gut.48.3.333.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kohoutová D, Bártová J, Tachecí I, et al. Cryptogenic multifocal ulcerous stenosing enteritis: a review of the literature. Gastroenterol Res Pract. 2013;2013: 918031. https://doi.org/10.1155/2013/918031.

Article  PubMed  PubMed Central  Google Scholar 

Debray C, Besancon F, Hardouin JP, Martin E, Marche C, Khoury K. Cryptogenetic plurifocal ulcerative stenosing enteritis. Arch Mal Appar Dig Mal Nutr. 1964;53:193–206.

CAS  PubMed  Google Scholar 

Morgenstern L, Freilich M, Panish JF. The circumferential small-bowel ulcer: clinical aspects in 17 patients. JAMA. 1965;191:637–40. https://doi.org/10.1001/jama.1965.03080080027006.

Article  CAS  PubMed  Google Scholar 

Lindholmer B, Nyman E, Raef L. Non-specific stenosing ulceration of the small bowel: a preliminary report. Acta Chir Scand. 1964;128:310–1.

CAS  PubMed  Google Scholar 

Lew C, Jain A, Chua J, Wong A. Cryptogenic multifocal ulcerous stenosing enteritis: a difficult diagnosis. ANZ J Surg. 2022;92:2373–5. https://doi.org/10.1111/ans.17489.

Article  PubMed  PubMed Central  Google Scholar 

Yan P, Li K, Cao Y, et al. What is the appropriate treatment strategy for cryptogenic multifocal ulcerative stenosing enteritis? A single-center experience from China. Front Med (Lausanne). 2022;9: 926800. https://doi.org/10.3389/fmed.2022.926800.

Article  PubMed  Google Scholar 

Hwang J, Kim JS, Kim AY, et al. Cryptogenic multifocal ulcerous stenosing enteritis: radiologic features and clinical behavior. World J Gastroenterol. 2017;23:4615–23. https://doi.org/10.3748/wjg.v23.i25.4615.

Article  PubMed  PubMed Central  Google Scholar 

Ramos GP, Bartlett DJ, Bledsoe AC, et al. Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE): a 20-year single-center clinical and radiologic experience. Abdom Radiol (NY). 2021;46:3798–809. https://doi.org/10.1007/s00261-021-03005-y.

Article  PubMed  Google Scholar 

Chung SH, Park SU, Cheon JH, et al. Clinical characteristics and treatment outcomes of cryptogenic multifocal ulcerous stenosing enteritis in Korea. Dig Dis Sci. 2015;60:2740–5. https://doi.org/10.1007/s10620-015-3595-y.

Article  PubMed  Google Scholar 

De Schepper H, Macken E, Van Marck V, Spinhoven M, Pelckmans P, Moreels T. Infliximab induces remission in cryptogenic multifocal ulcerous stenosing enteritis: first case. World J Gastroenterol. 2013;19:1661–4. https://doi.org/10.3748/wjg.v19.i10.1661.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Doutre LP, Paccalin J, Perissat J, Traissac FJ. Plurifocal ulcerous stenosing enteritis. A further case. Arch Fr Mal App Dig. 1966;55:537–40.

CAS  PubMed  Google Scholar 

Makharia GK, Srivastava S, Das P, et al. Clinical, endoscopic, and histological differentiations between Crohn’s disease and intestinal tuberculosis. Am J Gastroenterol. 2010;105:642–51. https://doi.org/10.1038/ajg.2009.585.

Article  PubMed  Google Scholar 

Kedia S, Sharma R, Nagi B, et al. Computerized tomography-based predictive model for differentiation of Crohn’s disease from intestinal tuberculosis. Indian J Gastroenterol. 2015;34:135–43. https://doi.org/10.1007/s12664-015-0550-y.

Article  PubMed  Google Scholar 

Singh SK, Srivastava A, Kumari N, Poddar U, Yachha SK, Pandey CM. Differentiation between Crohn disease and intestinal tuberculosis in children. J Pediatr Gastroenterol Nutr. 2018;66:e6–11. https://doi.org/10.1097/MPG.0000000000001625.

Article  PubMed  Google Scholar 

Seetharaman J, Srivastava A, Yadav RR, et al. Visceral fat indices: do they help differentiate Crohn’s disease and intestinal tuberculosis in children? J Crohns Colitis. 2023;17:2026–32. https://doi.org/10.1093/ecco-jcc/jjad109.

Article  PubMed  Google Scholar 

Chen D, Liu W, Zhou W, Zheng W, Wu D, Qian J. Retrospective study of the differential diagnosis between cryptogenic multifocal ulcerous stenosing enteritis and small bowel Crohn’s disease. BMC Gastroenterol. 2020;20:252. https://doi.org/10.1186/s12876-020-01389-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsumoto T, Iida M, Matsui T, Yao T. Chronic nonspecific multiple ulcers of the small intestine: a proposal of the entity from Japanese gastroenterologists to Western enteroscopists. Gastrointest Endosc. 2007;66:S99–107. https://doi.org/10.1016/j.gie.2007.01.004.

Article  PubMed  Google Scholar 

Ruemmele FM, Veres G, Kolho KL, et al. Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn’s disease. J Crohns Colitis. 2014;8:1179–207. https://doi.org/10.1016/j.crohns.2014.04.005.

Article  CAS  PubMed  Google Scholar 

Paustian FF, Bockus HL. So-called primary ulcerohypertrophic ileocecal tuberculosis. Am J Med. 1959;27:509–18. https://doi.org/10.1016/0002-9343(59)90016-6.

Article  CAS  PubMed  Google Scholar 

Makanjuola D. Is it Crohn’s disease or intestinal tuberculosis? CT analysis. Eur J Radiol. 1998;28:55–61. https://doi.org/10.1016/s0720-048x(97)00097-1.

Kijmassuwan T, Tanpowpong P, Molagool S, Treepongkaruna S. A rare cause of multiple small bowel ulcers and strictures in a 10-year old child. Turk J Gastroenterol. 2018;29:112–5. https://doi.org/10.5152/tjg.2018.17232.

Article  PubMed  PubMed Central  Google Scholar 

Uchida K, Nakajima A, Ushijima K, et al. Pediatric-onset chronic nonspecific multiple ulcers of small intestine: a nationwide survey and genetic study in Japan. J Pediatr Gastroenterol Nutr. 2017;64:565–8. https://doi.org/10.1097/MPG.0000000000001321.

Article  PubMed  Google Scholar 

Singh A, Sahu MK, Panigrahi MK, Misra D. Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE): a tale of three decades. ACG Case Rep J. 2017;4:e44. https://doi.org/10.14309/crj.2017.44.

Article  PubMed  PubMed Central  Google Scholar 

Sharma R, Kumble S, Madhusudhan, et al. Intestinal tuberculosis versus Crohn’s disease: clinical and radiological recommendations. Indian J Radiol Imaging. 2016;26:161–72. https://doi.org/10.4103/0971-3026.184417.

Article  PubMed  PubMed Central  Google Scholar 

Kim CW, Yu CS, Yoon YS, Yoon SN, Lim SB, Kim JC. Steroid-refractory cryptogenic multifocal ulcerous stenosing enteritis. Am J Surg. 2011;202:e48–51. https://doi.org/10.1016/j.amjsurg.2010.09.020.

Article  PubMed  Google Scholar 

Adler DH, Cogan JD, Phillips JA 3rd, et al. Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. J Clin Invest. 2008;118:2121–31. https://doi.org/10.1172/JCI30473.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Umeno J, Hisamatsu T, Esaki M, et al. A Hereditary enteropathy caused by mutations in the SLCO2A1 gene, encoding a prostaglandin transporter. PLoS Genet. 2015;11: e1005581. https://doi.org/10.1371/journal.pgen.1005581.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hosoe N, Ohmiya N, Hirai F, et al. Chronic enteropathy associated with SLCO2A1 gene [CEAS]—characterization of an enteric disorder to be considered in the differential diagnosis of Crohn’s disease. J Crohns Colitis. 2017;11:1277–81. https://doi.org/10.1093/ecco-jcc/jjx068.

Article  PubMed  Google Scholar 

Singh A. Cryptogenic multifocal ulcerating stenosing enteropathy (CMUSE) and/or chronic non-specific multiple ulcers of the small intestine (CNSU) and non-granulomatous ulcerating jejunoileitis (NGUJI). Curr Gastroenterol Rep. 2019;21:53. https://doi.org/10.1007/s11894-019-0721-6.

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