Brewster GS, Riegel B, Gehrman PR. Insomnia in the older adult. Sleep Med Clin. 2022;17(2):233–9.
Crowley K. Sleep and sleep disorders in older adults. Neuropsychol Rev. 2011;21(1):41–53.
Morin CM, Jarrin DC. Epidemiology of insomnia. Sleep Med Clin. 2022;17(2):173–91.
Patel D, Steinberg J, Patel P. Insomnia in the elderly: a review. J Clin Sleep Med. 2018;14(06):1017–24.
Article PubMed PubMed Central Google Scholar
Dzierzewski JM, Perez E, Ravyts SG, Dautovich N. Sleep and cognition. Sleep Med Clin. 2022;17(2):205–22.
Article PubMed PubMed Central Google Scholar
Rodenbeck A, Hajak G. Neuroendocrine dysregulation in primary insomnia. Rev Neurol (Paris). 2001;157(11 Pt 2):S57–S61.
Spiegel K, Leproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. Lancet. 1999;354(9188):1435–9.
Article CAS PubMed Google Scholar
Chen HW, Zhou R, Cao BF, Liu K, Zhong Q, Huang YN, Liu HM, Zhao JQ, Wu XB. The predictive, preventive, and personalized medicine of insomnia: gut microbiota and inflammation. EPMA J. 2023;14(4):571–83.
American Academy of Sleep Medicine. International classification of sleep disorders: diagnostic and coding manual. 3rd ed. Darien, IL: American Academy of Sleep Medicine; 2014.
Rezaie L, Fobian AD, McCall WV, Khazaie H. Paradoxical insomnia and subjective–objective sleep discrepancy: a review. Sleep Med Rev. 2018;40:196–202.
Martucci M, Conte M, Ostan R, Chiariello A, Miele F, Franceschi C, Salvioli S, Santoro A, Provini F. Both objective and paradoxical insomnia elicit a stress response involving mitokine production. Aging. 2020;12(11):10497–505.
Article CAS PubMed PubMed Central Google Scholar
Geyer JD, Lichstein KL, Ruiter ME, Ward LC, Carney PR, Dillard SC. Sleep education for paradoxical insomnia. Behav Sleep Med. 2011;9(4):266–72.
Article PubMed PubMed Central Google Scholar
van Soest APM, Hermes GDA, Berendsen AAM, van de Rest O, Zoetendal EG, Fuentes S, Santoro A, Franceschi C, de Groot LCPGM, de Vos WM. Associations between pro- and anti-inflammatory gastro-intestinal microbiota, diet, and cognitive functioning in Dutch healthy older adults: The NU-AGE study. Nutrients. 2020;12(11):3471.
Article PubMed PubMed Central Google Scholar
Sen P, Molinero-Perez A, O’Riordan KJ, McCafferty CP, O’Halloran KD, Cryan JF. Microbiota and sleep: awakening the gut feeling. Trends Mol Med. 2021;27(10):935–45.
Article CAS PubMed Google Scholar
Mitrea L, Nemeş S-A, Szabo K, Teleky B-E, Vodnar D-C. Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders. Front Med. 2022;9:813204.
Neroni B, Evangelisti M, Radocchia G, Di Nardo G, Pantanella F, Villa MP, Schippa S. Relationship between sleep disorders and gut dysbiosis: what affects what? Sleep Med. 2021;87:1–7.
Wang Q, Chen B, Sheng D, Yang J, Fu S, Wang J, Zhao C, Wang Y, Gai X, Wang J, Stirling K, Heng X, Man H, Zhang L. Multiomics analysis reveals aberrant metabolism and immunity; inked gut microbiota with insomnia. Microbiology Spectrum. 2022;10(5):e0099822.
Wang Z, Wang Z, Lu T, Chen W, Yan W, Yuan K, Shi L, Liu X, Zhou X, Shi J, Vitiello MV, Han Y, Lu L. The microbiota-gut-brain axis in sleep disorders. Sleep Med Rev. 2022;65:101691.
Article CAS PubMed Google Scholar
Tang M, Song X, Zhong W, Xie Y, Liu Y, Zhang X. Dietary fiber ameliorates sleep disturbance connected to the gut-brain axis. Food Funct. 2022;13(23):12011–20.
Article CAS PubMed Google Scholar
Gil-Hernández E, Ruiz-González C, Rodriguez-Arrastia M, Ropero-Padilla C, Rueda-Ruzafa L, Sánchez-Labraca N, Roman P. Effect of gut microbiota modulation on sleep: a systematic review and meta-analysis of clinical trials. Nutr Rev. 2023;81(12):1556–70.
Boyko N, Costigliola V, Golubnitschaja O. Microbiome in the framework of predictive, preventive and personalised medicine. In: Boyko N, Golubnitschaja O, editors. Microbiome in 3P medicine strategies: the first exploitation guide. Cham: Springer. In: Boyko N, Golubnitschaja O, editors. Microbiome in 3P medicine strategies: the first exploitation guide. Cham: Springer International Publishing; 2023. p. 1–8.
Shimizu Y, Yamamura R, Yokoi Y, Ayabe T, Ukawa S, Nakamura K, Okada E, Imae A, Nakagawa T, Tamakoshi A, Nakamura K. Shorter sleep time relates to lower human defensin 5 secretion and compositional disturbance of the intestinal microbiota accompanied by decreased short-chain fatty acid production. Gut Microbes. 2023;15(1):2190306.
Feng W, Yang Z, Liu Y, Chen R, Song Z, Pan G, Zhang Y, Guo Z, Ding X, Chen L, Wang Y. Gut microbiota: a new target of traditional Chinese medicine for insomnia. Biomed Pharmacother. 2023;160:114344.
Article CAS PubMed Google Scholar
Holzhausen EA, Peppard PE, Sethi AK, Safdar N, Malecki KC, Schultz AA, Deblois CL, Hagen EW. Associations of gut microbiome richness and diversity with objective and subjective sleep measures in a population sample. Sleep. 2023;47(3):zsad300.
Duvallet C, Gibbons SM, Gurry T, Irizarry RA, Alm EJ. Meta-analysis of gut microbiome studies identifies disease-specific and shared responses. Nat Comm. 2017;8(1):1784.
Liu B, Lin W, Chen S, Xiang T, Yang Y, Yin Y, Xu G, Liu Z, Liu L, Pan J, Xie L. Gut microbiota as an objective measurement for auxiliary diagnosis of insomnia disorder. Front Microbiol. 2019;10:1770.
Article PubMed PubMed Central Google Scholar
Franceschi C, Garagnani P, Morsiani C, Conte M, Santoro A, Grignolio A, Monti D, Capri M, Salvioli S. The continuum of aging and age-related diseases: common mechanisms but different rates. Front Med. 2018;5:61.
Zhao M, Tuo H, Wang S, Zhao L. The effects of dietary nutrition on sleep and sleep disorders. Mediators Inflamm. 2020;2020:3142874.
Article PubMed PubMed Central Google Scholar
Santoro A, Pini E, Scurti M, Palmas G, Berendsen A, Brzozowska A, Pietruszka B, Szczecinska A, Cano N, Meunier N, de Groot CPGM, Feskens E, Fairweather-Tait S, Salvioli S, Capri M, Brigidi P, Franceschi C, NU-AGE Consortium. Combating inflammaging through a Mediterranean whole diet approach: the NU-AGE project’s conceptual framework and design. Mech Ageing Dev. 2014;136–137:3–13.
Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24(4):385–96.
Article CAS PubMed Google Scholar
Berendsen A, Santoro A, Pini E, Cevenini E, Ostan R, Pietruszka B, Rolf K, Cano N, Caille A, Lyon-Belgy N, Fairweather-Tait S, Feskens E, Franceschi C, de Groo CPM. A parallel randomized trial on the effect of a healthful diet on inflammageing and its consequences in European elderly people: design of the NU-AGE dietary intervention study. Mech Ageing Dev. 2013;134(11–12):523–30.
Ostan R, Guidarelli G, Giampieri E, Lanzarini C, Berendsen AAM, Januszko O, Jennings A, Lyon N, Caumon E, Gillings R, Sicinska E, Meunier N, Feskens EJM, Pietruszka B, de Groot LCPGM, Fairweather-Tait S, Capri M, Franceschi C, Santoro A. Cross-sectional analysis of the correlation between daily nutrient intake assessed by 7-day food records and biomarkers of dietary intake among participants of the NU-AGE study. Front Physiol. 2018;9:1359.
Article PubMed PubMed Central Google Scholar
Berendsen A, van de Rest O, Feskens E, Santoro A, Ostan R, Pietruszka B, Brzozowska A, Stelmaszczyk-Kusz A, Jennings A, Gillings R, Cassidy A, Caille A, Caumon E, Malpuech-Brugere C, Franceschi C, de Groot L. Changes in dietary intake and adherence to the NU-AGE diet following a one-year dietary intervention among European older adults—results of the NU-AGE randomized trial. Nutrients. 2018;10(12):1905.
Article PubMed PubMed Central Google Scholar
Barone M, Garelli S, Rampelli S, Agostini A, Matysik S, D’Amico F, Krautbauer S, Mazza R, Salituro N, Fanelli F, Iozzo P, Sanz Y, Candela M, Brigidi P, Pagotto U, Turroni S. Multi-omics gut microbiome signatures in obese women: role of diet and uncontrolled eating behavior. BMC Med. 2022;20:500.
Article CAS PubMed PubMed Central Google Scholar
Masella AP, Bartram AK, Truszkowski JM, Brown DG, Neufeld JD. PANDAseq: paired-end assembler for Illumina sequences. BMC Bioinformatic
Comments (0)