T.H. received research funding from Chugai Pharmaceutical, Otsuka Pharmaceutical, Kyowa Kirin and Sumitomo Pharma. M.A. received research funding from Chugai Pharmaceutical, Sanofi K.K., Pfizer Seiyaku K.K., Kyowa Kirin, Janssen Pharma K.K., Takeda Pharmaceutical, Teijin Pharma, and Ono Pharmaceutical, and honoraria from Daiichi Sankyo Company. The other authors declare no competing financial interests.