Fine particulate matter aggravates smoking induced lung injury via NLRP3/caspase-1 pathway in COPD

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, et al. Global strategy for the diagnosis, management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary. Am J Respir Crit Care Med. 2017;195:557–82.

Article  CAS  PubMed  Google Scholar 

Lamprecht B, McBurnie MA, Vollmer WM, Gudmundsson G, Welte T, Nizankowska-Mogilnicka E, Studnicka M, Bateman E, Anto JM, Burney P, et al. COPD in never smokers: results from the population-based burden of obstructive lung disease study. Chest. 2011;139:752–63.

Article  PubMed  PubMed Central  Google Scholar 

Tan WC, Sin DD, Bourbeau J, Hernandez P, Chapman KR, Cowie R, FitzGerald JM, Marciniuk DD, Maltais F, Buist AS, et al. Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study. Thorax. 2015;70:822–9.

Article  CAS  PubMed  Google Scholar 

Salvi SS, Barnes PJ. Chronic obstructive pulmonary disease in non-smokers. Lancet. 2009;374:733–43.

Article  PubMed  Google Scholar 

Paulin LM, Diette GB, Blanc PD, Putcha N, Eisner MD, Kanner RE, Belli AJ, Christenson S, Tashkin DP, Han M, et al. Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015;191:557–65.

Article  PubMed  PubMed Central  Google Scholar 

Gan WQ, FitzGerald JM, Carlsten C, Sadatsafavi M, Brauer M. Associations of ambient air pollution with chronic obstructive pulmonary disease hospitalization and mortality. Am J Respir Crit Care Med. 2013;187:721–7.

Article  PubMed  Google Scholar 

Liu S, Zhou Y, Liu S, Chen X, Zou W, Zhao D, Li X, Pu J, Huang L, Chen J, et al. Association between exposure to ambient particulate matter and chronic obstructive pulmonary disease: results from a cross-sectional study in China. Thorax. 2017;72:788–95.

Article  PubMed  Google Scholar 

Lamichhane DK, Leem JH, Kim HC. Associations between Ambient Particulate Matter and Nitrogen Dioxide and Chronic Obstructive Pulmonary diseases in adults and effect modification by demographic and lifestyle factors. Int J Environ Res Public Health 2018, 15.

Dai L, Zanobetti A, Koutrakis P, Schwartz JD. Associations of fine particulate matter species with mortality in the United States: a multicity time-series analysis. Environ Health Perspect. 2014;122:837–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Doiron D, de Hoogh K, Probst-Hensch N, Fortier I, Cai Y, De Matteis S, Hansell AL. Air pollution, lung function and COPD: results from the population-based UK Biobank study. Eur Respir J 2019, 54.

Xue H, Li MX. MicroRNA-150 protects against cigarette smoke-induced lung inflammation and airway epithelial cell apoptosis through repressing p53: MicroRNA-150 in CS-induced lung inflammation. Hum Exp Toxicol. 2018;37:920–8.

Article  CAS  PubMed  Google Scholar 

Pan X, Xu K, Li Y, Wang X, Peng X, Li M, Li Y. Interleukin-35 expression protects against cigarette smoke-induced lung inflammation in mice. Biomed Pharmacother. 2019;110:727–32.

Article  CAS  PubMed  Google Scholar 

Li C, Chen J, Yuan W, Zhang W, Chen H, Tan H. Preventive effect of ursolic acid derivative on particulate matter 2.5-induced chronic obstructive pulmonary disease involves suppression of lung inflammation. IUBMB Life. 2020;72:632–40.

Article  CAS  PubMed  Google Scholar 

Ogino K, Nagaoka K, Okuda T, Oka A, Kubo M, Eguchi E, Fujikura Y. PM2.5-induced airway inflammation and hyperresponsiveness in NC/Nga mice. Environ Toxicol. 2017;32:1047–54.

Article  CAS  PubMed  Google Scholar 

Zheng R, Tao L, Jian H, Chang Y, Cheng Y, Feng Y, Zhang H. NLRP3 inflammasome activation and lung fibrosis caused by airborne fine particulate matter. Ecotoxicol Environ Saf. 2018;163:612–9.

Article  CAS  PubMed  Google Scholar 

Vij N, Chandramani-Shivalingappa P, Van Westphal C, Hole R, Bodas M. Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis. Am J Physiol Cell Physiol. 2018;314:C73–87.

Article  PubMed  Google Scholar 

Wang Y, Zhong Y, Liao J, Wang G. PM2.5-related cell death patterns. Int J Med Sci. 2021;18:1024–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miao EA, Rajan JV, Aderem A. Caspase-1-induced pyroptotic cell death. Immunol Rev. 2011;243:206–14.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bergsbaken T, Fink SL, Cookson BT. Pyroptosis: host cell death and inflammation. Nat Rev Microbiol. 2009;7:99–109.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rathinam VA, Fitzgerald KA. Inflammasome complexes: emerging mechanisms and Effector functions. Cell. 2016;165:792–800.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barbe F, Douglas T, Saleh M. Advances in nod-like receptors (NLR) biology. Cytokine Growth Factor Rev. 2014;25:681–97.

Article  CAS  PubMed  Google Scholar 

Latz E, Xiao TS, Stutz A. Activation and regulation of the inflammasomes. Nat Rev Immunol. 2013;13:397–411.

Article  CAS  PubMed  Google Scholar 

Nachmias N, Langier S, Brzezinski RY, Siterman M, Stark M, Etkin S, Avriel A, Schwarz Y, Shenhar-Tsarfaty S, Bar-Shai A. NLRP3 inflammasome activity is upregulated in an in-vitro model of COPD exacerbation. PLoS ONE. 2019;14:e0214622.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang MY, Jiang YX, Yang YC, Liu JY, Huo C, Ji XL, Qu YQ. Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway. Life Sci. 2021;269:119090.

Article  CAS  PubMed  Google Scholar 

Xiong R, Jiang W, Li N, Liu B, He R, Wang B, Geng Q. PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice. Ecotoxicol Environ Saf. 2021;221:112433.

Article  CAS  PubMed  Google Scholar 

Li J, An Z, Song J, Du J, Zhang L, Jiang J, Ma Y, Wang C, Zhang J, Wu W. Fine particulate matter-induced lung in fl ammation is mediated by pyroptosis in mice. Ecotoxicol Environ Saf. 2021;219:112351.

Article  CAS  PubMed  Google Scholar 

Jia H, Liu Y, Guo D, He W, Zhao L, Xia S. PM2.5-induced pulmonary inflammation via activating of the NLRP3/caspase-1 signaling pathway. Environ Toxicol. 2021;36:298–307.

Article  CAS  PubMed  Google Scholar 

Zhao J, Li M, Wang Z, Chen J, Zhao J, Xu Y, Wei X, Wang J, Xie J. Role of PM2.5 in the development and progression of COPD and its mechanisms. Respir Res. 2019;20:120.

Article  PubMed  PubMed Central  Google Scholar 

Wang Z, Zhao J, Wang T, Du X, Xie J. Fine-particulate matter aggravates cigarette smoke extract-induced airway inflammation via Wnt5a-ERK pathway in COPD. Int J Chron Obstruct Pulmon Dis. 2019;14:979–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park S, Ra SW, Kang SY, Kim HC, Lee SW. Effect of particulate matter exposure on patients with COPD and risk reduction through behavioural interventions: the protocol of a prospective panel study. BMJ Open. 2020;10:e039394.

Article  PubMed  PubMed Central  Google Scholar 

Kim H, Na G, Park S, Ra SW, Kang SY, Kim HC, Kim HC, Lee SW. The impact of life behavior and environment on particulate matter in chronic obstructive pulmonary disease. Environ Res. 2021;198:111265.

Article  CAS  PubMed  Google Scholar 

Huh J-Y, Kim H, Na G, Park S, Ra SW, Kang S-Y, Kim HC, Kim H-C, Lee SW. Effects of outdoors and indoors particulate matter 2.5 on COPD: Multicenter prospective observational study. Eur Respir J. 2021;58:PA1788.

Google Scholar 

Sun B, Shi Y, Li Y, Jiang J, Liang S, Duan J, Sun Z. Short-term PM(2.5) exposure induces sustained pulmonary fibrosis development during post-exposure period in rats. J Hazard Mater. 2020;385:121566.

Article  CAS  PubMed  Google Scholar 

Kim KH, Park TS, Kim YS, Lee JS, Oh YM, Lee SD, Lee SW. Resolvin D1 prevents smoking-induced emphysema and promotes lung tissue regeneration. Int J Chron Obstruct Pulmon Dis. 2016;11:1119–28.

CAS  PubMed  PubMed Central  Google Scholar 

Huh JW, Kim SY, Lee JH, Lee JS, Van Ta Q, Kim M, Oh YM, Lee YS, Lee SD. Bone marrow cells repair cigarette smoke-induced emphysema in rats. Am J Physiol Lung Cell Mol Physiol. 2011;301:L255–266.

Article  CAS  PubMed  Google Scholar 

Lee SH, Kim J, Kim NH, Kim OH, Shon CH, Kim SJ, Jang Y, Yun S, Lim SE, Jung SY, et al. Gut microbiota composition and metabolite profiling in smokers: a comparative study between emphysema and asymptomatic individuals with therapeutic implications. Thorax. 2023;78:1080–9.

Article  PubMed  Google Scholar 

Jang YO, Kim OH, Kim SJ, Lee SH, Yun S, Lim SE, Yoo HJ, Shin Y, Lee SW. High-fiber diets attenuate emphysema development via modulation of gut microbiota and metabolism. Sci Rep. 2021;11:7008.

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