Secretome hypoxia-mesenchymal stem cells decrease tumor necrosis factor-α and interleukin-18 in kidney of type 2 diabetes mellitus model rats

Abo El- Nasr NME, Saleh DO, Mahmoud SS, et al. Olmesartan attenuates type 2 diabetes-associated liver injury: cross-talk of AGE/RAGE/JNK, STAT3/SCOS3 and RAS signaling pathways. Eur J Pharmacol 2020;874:173010. doi:10.1016/j.ejphar.2020.173010.

Adel Abdel-Moneim, Sanaa M. Abd El-Twab, Nabil A, Salma A. El Kazafy. Effect of antidiabetic therapy on TNF-α, IL-18, IL-23 and IL-35 levels in T2DM patients with coincidental Helicobacter pylori infection. J Taibah Univ Sci 2020;14:1377-85. doi:10.1080/16583655.2020.1824669.

Sharma I, Liao Y, Zheng X, Kanwar YS. New pandemic: obesity and associated nephropathy. Front Med (Lausanne) 2021;8:673556. doi:10.3389/fmed.2021.673556.

Zaharieva E, Kamenov Z, Velikova T, Tsakova A, El-Darawish Y, Okamura H. Interleukin-18 serum level is elevated in type 2 diabetes and latent autoimmune diabetes. Endocr Connect 2018;7:179-85. doi:10.1530/EC-17-0273.

Sawaf H, Thomas G, Taliercio JJ, et al. Therapeutic advances in diabetic nephropathy. J Clin Med 2022;11 : 378. doi: 10.3390/jcm11020378.

Boi R, Ebefors K, Henricsson M, Borén J, Nyström J. Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions. Sci Rep 2022;12:7322. doi:10.1038/s41598-022-10907-4.

Dias I, Pinheiro D, Ribeiro Silva K, et al. Secretome effect of adipose tissue-derived stem cells cultured two-dimensionally and three-dimensionally in mice with streptozocin induced type 1 diabetes. Curr Res Pharmacol Drug Discov 2021;2:100069. doi:10.1016/j.crphar.2021.100069.

Nguyen LT, Hoang DM, Nguyen KT, et al. Type 2 diabetes mellitus duration and obesity alter the efficacy of autologously transplanted bone marrow-derived mesenchymal stem/stromal cells. Stem Cells Transl Med 2021;10:1266-78. doi:10.1002/sctm.20-0506.

Sávio-Silva C, Beyerstedt S, Soinski-Sousa PE, et al. Mesenchymal stem cell therapy for diabetic kidney disease: a review of the studies using syngeneic, autologous, allogeneic, and xenogeneic cells. Stem Cells Int 2020;2020: 8833725. doi:10.1155/2020/8833725.

Song C, Wang S, Fu Z, et al. IGFBP5 promotes diabetic kidney disease progression by enhancing PFKFB3-mediated endothelial glycolysis. Cell Death Dis 2022;13:340. doi:10.1038/s41419-022-04803-y.

World Health Organization. Obesity and overweight. Geneva : World Health Organization;2021.

Yu M, Ma L, Yuan Y, et al. Cranial suture regeneration mitigates skull and neurocognitive defects in craniosynostosis. Cell 2021;184:243-56.e18. doi:10.1016/j.cell.2020.11.037.

Su Y, Xu C, Cheng W, Zhao Y, Sui L, Zhao Y. Pretreated mesenchymal stem cells and their secretome: enhanced immunotherapeutic strategies. Int J Mol Sci 2023;24: 1277. doi:10.3390/ijms24021277.

Raggi F, Pelassa S, Pierobon D, et al. Regulation of human macrophage M1-M2 polarization balance by hypoxia and the triggering receptor expressed on myeloid cells-1. Front Immunol 2017;8:1-18. doi:10.3389/fimmu.2017.01097.

Lin W, Li HY, Yang Q, et al. Administration of mesenchymal stem cells in diabetic kidney disease: a systematic review and meta-analysis. Stem Cell Res Ther 2021;12:43. doi:10.1186/s13287-020-02108-5.

Chadid T, Morris A, Surowiec A, et al. Reversible secretome and signaling defects in diabetic mesenchymal stem cells from peripheral arterial disease patients. J Vasc Surg 2018;68:137S-51S.e2. doi:10.1016/j.jvs.2018.05.223.

Putra A, Ridwan FB, Putridewi AI, et al. The role of tnf-α induced mscs on suppressive inflammation by increasing tgf-β and il-10. Open Access Maced J Med Sci 2018;6:1779-83. doi:10.3889/oamjms.2018.404.

Ozkan S, Isildar B, Ercin M, et al. Therapeutic potential of conditioned medium obtained from deferoxamine preconditioned umbilical cord mesenchymal stem cells on diabetic nephropathy model. Stem Cell Res Ther 2022;13:438. doi:10.1186/s13287-022-03121.6

Sutrisman IP, Antari AD, Putra A, Irawan RCS, Handoyo FE. Secretome hypoxia-mesenchymal stem cells regulate IL-10 concentrations in STZ-induced type 1 diabetes rats. Int J Cell Biomed Sci 2022;1:56-64.

Holthaus M, Santhakumar N, Wahlers T, Paunel-Görgülü A. The secretome of preconditioned mesenchymal stem cells drives polarization and reprogramming of M2a macrophages toward an IL-10-producing phenotype. Int J Mol Sci 2022;23: 4104. doi:10.3390/ijms23084104.

Putra A, Pertiwi D, Milla MN, et al. Hypoxia-preconditioned MSCs have superior effect in ameliorating renal function on acute renal failure animal model. Open Access Maced J Med Sci 2019;7:305-10. doi:10.3889/oamjms.2019.049.

Muhar AM, Putra A, Warli SM, Munir D. Hypoxia-mesenchymal stem cells inhibit intra-peritoneal adhesions formation by upregulation of the il-10 expression. Open Access Maced J Med Sci 2019;7:3937-43. doi:10.3889/oamjms.2019.713.

Donate-Correa J, Ferri CM, Sánchez-Quintana F, et al. Inflammatory cytokines in diabetic kidney disease: pathophysiologic and therapeutic implications. Front Med (Lausanne) 2021;7: 628289. doi:10.3389/fmed.2020.628289.

Mühl H, Dhingra S, Booz GW, et al. IL-10/STAT3/SOCS3 axis is involved in the anti-inflammatory effect of benznidazole. Front Immunol 2019;10:1267. doi:10.3389/fimmu.2019.01267

Saraiva M, O’Garra A. The regulation of IL-10 production by immune cells. Nat Rev Immunol 2010;10:170-81. doi:10.1038/nri2711.

Astari L, Cahyono H, Widjajanto E. Correlation of interleukin-10, superoxide dismutase (SOD), and malondialdehyde (MDA) levels with HbA1c in pediatric type 1 diabetes mellitus. J Trop Life Sci 2017;7:286-92. doi:10.11594/jtls.07.03.15.

Kotsis V, Martinez F, Trakatelli C, Redon J. Impact of obesity in kidney diseases. Nutrients 2021;13: 4482. doi:10.3390/nu13124482.

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