Assessing the Impact of Bariatric Surgery on Retinol-Binding Protein 4 (RBP4): A Systematic Review and Meta-Analysis

Alshubrami S, et al. Impact of gastric sleeve surgery on plasma retinol binding protein 4 and adipsin levels in healthy male population. Pak J Med Sci. 2020;36(7):1495–9.

Article  PubMed  PubMed Central  Google Scholar 

Bloomberg RD, et al. Nutritional deficiencies following bariatric surgery: what have we learned? Obes Surg. 2005;15(2):145–54.

Article  PubMed  Google Scholar 

Zhou W, et al. Involvement of RBP4 in diabetic atherosclerosis and the role of vitamin D intervention. J Diabetes Res. 2018;2018:7329861.

Haider DG, et al. Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects. J Clin Endocrinol Metab. 2007;92(3):1168–71.

Article  CAS  PubMed  Google Scholar 

Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Investig. 2000;106(4):473–81.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Perseghin G, et al. Metabolic defects in lean nondiabetic offspring of NIDDM parents: a cross-sectional study. Diabetes. 1997;46(6):1001–9.

Article  CAS  PubMed  Google Scholar 

Yang Q, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature. 2005;436(7049):356–62.

Article  ADS  CAS  PubMed  Google Scholar 

Graham TE, et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med. 2006;354(24):2552–63.

Article  CAS  PubMed  Google Scholar 

Faqihi EJ, et al. The effect of bariatric surgery on the relation between retinol-binding protein 4 (RBP4) and vitamin D plasma levels in male obese population. Cureus. 2022;14(12):e32733.

PubMed  PubMed Central  Google Scholar 

von Eynatten M, et al. Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease. Diabetologia. 2007;50(9):1930–7.

Article  Google Scholar 

Qi Q, et al. Elevated retinol-binding protein 4 levels are associated with metabolic syndrome in Chinese people. J Clin Endocrinol Metab. 2007;92(12):4827–34.

Article  CAS  PubMed  Google Scholar 

Lee JW, et al. Visceral adiposity is associated with serum retinol binding protein-4 levels in healthy women. Obesity (Silver Spring). 2007;15(9):2225–32.

Article  CAS  PubMed  Google Scholar 

Kotnik P, Fischer-Posovszky P, Wabitsch M. RBP4: a controversial adipokine. Eur J Endocrinol. 2011;165(5):703–11.

Article  CAS  PubMed  Google Scholar 

Nono Nankam, PA and Blüher M. Retinol-binding protein 4 in obesity and metabolic dysfunctions. Mol Cell Endocrinol. 2021;531:111312

Klöting N, et al. Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass. Cell Metab. 2007;6(1):79–87.

Article  PubMed  Google Scholar 

Broch M, et al. Association of retinol-binding protein-4 (RBP4) with lipid parameters in obese women. Obes Surg. 2010;20(9):1258–64.

Article  PubMed  Google Scholar 

Bachmayer C, et al. Healthy obese and post bariatric patients - metabolic and vascular patterns. Exp Clin Endocrinol Diabetes. 2013;121(8):483–7.

Article  CAS  PubMed  Google Scholar 

Gómez-Ambrosi J, et al. Serum retinol-binding protein 4 is not increased in obesity or obesity-associated type 2 diabetes mellitus, but is reduced after relevant reductions in body fat following gastric bypass. Clin Endocrinol (Oxf). 2008;69(2):208–15.

Article  PubMed  Google Scholar 

Hany M, et al. Can leptin/ghrelin ratio and retinol-binding protein 4 predict improved insulin resistance in patients with obesity undergoing sleeve gastrectomy? Obes Surg. 2022;32(12):3942–50.

Article  PubMed  PubMed Central  Google Scholar 

Oberbach A, et al. Combined serum proteomic and metabonomic profiling after laparoscopic sleeve gastrectomy in children and adolescents. J Laparoendosc Adv Surg Tech. 2012;22(2):184–8.

Article  Google Scholar 

Siejka A, et al. Long-term impact of vertical banded gastroplasty (VBG) on plasma concentration of leptin, soluble leptin receptor, ghrelin, omentin-1, obestatin, and retinol binding protein 4 (RBP4) in patients with severe obesity. Cytokine. 2013;64(2):490–3.

Article  CAS  PubMed  Google Scholar 

Swarbrick MM, et al. Longitudinal changes in pancreatic and adipocyte hormones following Roux-en-Y gastric bypass surgery. Diabetologia. 2008;51(10):1901–11.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang X, et al. Changes of serum retinol-binding protein 4 associated with improved insulin resistance after laparoscopic sleeve gastrectomy in Chinese obese patients. Diabetol Metab Syndr. 2020;12:7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tschoner A, et al. Retinol-binding protein 4, visceral fat, and the metabolic syndrome: effects of weight loss. Obesity (Silver Spring). 2008;16(11):2439–44.

Article  CAS  PubMed  Google Scholar 

Kalani A, et al. The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis. Obes Sci Pract. 2017;3(3):319–32.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brzozowska MM, et al. Effects of bariatric surgery and dietary intervention on insulin resistance and appetite hormones over a 3 year period. Sci Rep. 2023;13(1):6032.

Jüllig M, et al. Lower fetuin-A, retinol binding protein 4 and several metabolites after gastric bypass compared to sleeve gastrectomy in patients with type 2 diabetes. PLoS ONE. 2014;9(5):e96489.

Article  ADS  PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif