Patients who live with advanced breast cancer (ABC) face many challenges: an incurable chronic disease with shorter survival time; frequent medical treatments, chronic side effects (eg, functional and occupational disability, pain, fatigue, cognitive impairment, sexual dysfunction), and practical concerns (eg, work and family role disruption, financial strain). The impact of the initial diagnosis of cancer is “revisited” at multidimensional levels: physical, psychological/emotional, family, social, existential, occupational, financial, spiritual, etc., and an insidious and pervasive uncertainty about the future and the threat of dying follows the patient throughout their life.1 Patients facing ABC are more discouraged, and less hopeful, and are at greater risk for emotional severe distress, including symptoms of depression and anxiety, as well as existential distress and loneliness.1 The prevalence of severe distress has been estimated as 32% and above in early breast cancer (BC),2 can affect more than 60% of ABC women and this number increases with the progression of disease.3 As such it is of utmost importance to regularly screen for distress and psychosocial needs in this population and address them adequately during their treatment and care to ensure the best quality cancer treatment and care.