Yokoyama Y, Fukaya M, Mizuno T, Ebata T, Asahara T, Nagino M. Clinical importance of “occult-bacterial translocation” in patients undergoing highly invasive gastrointestinal surgery: a review. Surg Today. 2021;51:485–92.
Mizuno T, Yokoyama Y, Nishio H, Ebata T, Sugawara G, Asahara T, et al. Intraoperative bacterial translocation detected by bacterium-specific ribosomal rna-targeted reverse-transcriptase polymerase chain reaction for the mesenteric lymph node strongly predicts postoperative infectious complications after major hepatectomy for biliary malignancies. Ann Surg. 2010;252:1013–9.
Yokoyama Y, Nishigaki E, Abe T, Fukaya M, Asahara T, Nomoto K, et al. Randomized clinical trial of the effect of perioperative synbiotics versus no synbiotics on bacterial translocation after oesophagectomy. Br J Surg. 2014;101:189–99.
Fukaya M, Yokoyama Y, Usui H, Fujieda H, Sakatoku Y, Takahashi T, et al. Impact of synbiotics treatment on bacteremia induced during neoadjuvant chemotherapy for esophageal cancer: a randomised controlled trial. Clin Nutr. 2021;40:5781–91.
Søby JH, Watt SK, Vogelsang RP, Servant F, Lelouvier B, Raskov H, et al. Alterations in blood microbiota after colonic cancer surgery. BJS Open. 2020;4:1227–37.
Article PubMed PubMed Central Google Scholar
Mutignani M, Penagini R, Gargari G, Guglielmetti S, Cintolo M, Airoldi A, et al. Blood bacterial DNA load and profiling differ in colorectal cancer patients compared to tumor-free controls. Cancers (Basel). 2021;13:6363.
Sakaguchi S, Saito M, Tsuji H, Asahara T, Takata O, Fujimura J, et al. Bacterial rRNA-targeted reverse transcription-PCR used to identify pathogens responsible for fever with neutropenia. J Clin Microbiol. 2010;48:1624–8.
Article PubMed PubMed Central Google Scholar
Coburn B, Morris AM, Tomlinson G, Detsky AS. Does this adult patient with suspected bacteremia require blood cultures? JAMA. 2012;308:502–11.
Niikura M, Atobe S, Takahashi A, Kado Y, Sugimoto T, Tsuji H, et al. Development of a rapid and sensitive analytical system for. Emerg Microbes Infect. 2021;10:677–86.
Article PubMed PubMed Central Google Scholar
Suenaga M, Yokoyama Y, Fujii T, Yamada S, Yamaguchi J, Hayashi M, et al. Impact of preoperative occult-bacterial translocation on surgical site infection in patients undergoing pancreatoduodenectomy. J Am Coll Surg. 2021;232:298–306.
Iida T, Kaido T, Yagi S, Yoshizawa A, Hata K, Mizumoto M, et al. Posttransplant bacteremia in adult living donor liver transplant recipients. Liver Transpl. 2010;16:1379–85.
Yao S, Yagi S, Uozumi R, Iida T, Nagao M, Okamura Y, et al. A high portal venous pressure gradient increases gut-related bacteremia and consequent early mortality after living donor liver transplantation. Transplantation. 2018;102:623–31.
Albillos A, de Gottardi A, Rescigno M. The gut-liver axis in liver disease: pathophysiological basis for therapy. J Hepatol. 2020;72:558–77.
Kaido T, Ogawa K, Mori A, Fujimoto Y, Ito T, Tomiyama K, et al. Usefulness of the Kyoto criteria as expanded selection criteria for liver transplantation for hepatocellular carcinoma. Surgery. 2013;154:1053–60.
Alpern ER, Alessandrini EA, Bell LM, Shaw KN, McGowan KL. Occult bacteremia from a pediatric emergency department: current prevalence, time to detection, and outcome. Pediatrics. 2000;106:505–11.
Yao S, Yagi S. Analyses focused on organisms would enhance the value of detecting occult bacteremia. J Am Coll Surg. 2021;233:161–2.
Sato J, Kanazawa A, Ikeda F, Yoshihara T, Goto H, Abe H, et al. Gut dysbiosis and detection of “live gut bacteria” in blood of Japanese patients with type 2 diabetes. Diabetes Care. 2014;37:2343–50.
Nishigaki E, Abe T, Yokoyama Y, Fukaya M, Asahara T, Nomoto K, et al. The detection of intraoperative bacterial translocation in the mesenteric lymph nodes is useful in predicting patients at high risk for postoperative infectious complications after esophagectomy. Ann Surg. 2014;259:477–84.
Yao S, Yagi S, Ogawa E, Hirata M, Miyachi Y, Iwamura S, et al. Dysbiosis and depletion of fecal organic acids correlate with the severity of rejection after rat liver transplantation. Transpl Int. 2022;35:10728.
Article PubMed PubMed Central Google Scholar
Yao S, Yagi S, Hirata M, Miyachi Y, Ogawa E, Uozumi R, et al. Chronological changes in the gut microbiota and intestinal environment in recipients and donors of living donor liver transplantation. J Hepatobiliary Pancreat Sci. 2023;30:439–52.
Camilleri M. Leaky gut: mechanisms, measurement and clinical implications in humans. Gut. 2019;68:1516–26.
Lakbar I, Einav S, Lalevée N, Martin-Loeches I, Pastene B, Leone M. Interactions between gender and sepsis-implications for the future. Microorganisms. 2023;11:746.
Article PubMed PubMed Central Google Scholar
Bang CS, Yoon JH, Kim YJ, Kim JB, Baik GH, Suk KT, et al. Clinical impact of body mass index on bactibilia and bacteremia. BMC Gastroenterol. 2014;14:104.
Article PubMed PubMed Central Google Scholar
Pepper DJ, Demirkale CY, Sun J, Rhee C, Fram D, Eichacker P, et al. Does obesity protect against death in sepsis? A retrospective cohort study of 55,038 adult patients. Crit Care Med. 2019;47:643–50.
Article PubMed PubMed Central Google Scholar
Lebovitz S, Rozen G, Abu Ghosh Z, Korem M, Elinav H, Zayyad H, et al. The relationship between body mass index and in-hospital mortality in bacteremic sepsis. J Clin Med. 2023;12:3848.
Article PubMed PubMed Central Google Scholar
Asahara T, Takahashi A, Yuki N, Kaji R, Takahashi T, Nomoto K. Protective effect of a synbiotic against multidrug-resistant acinetobacter baumannii in a murine infection model. Antimicrob Agents Chemother. 2016;60:3041–50.
Article PubMed PubMed Central Google Scholar
Asahara T, Shimizu K, Takada T, Kado S, Yuki N, Morotomi M, et al. Protective effect of Lactobacillus casei strain Shirota against lethal infection with multi-drug resistant Salmonella enterica serovar Typhimurium DT104 in mice. J Appl Microbiol. 2011;110:163–73.
Feng Y, Wang Y, Wang P, Huang Y, Wang F. Short-chain fatty acids manifest stimulative and protective effects on intestinal barrier function through the inhibition of NLRP3 inflammasome and autophagy. Cell Physiol Biochem. 2018;49:190–205.
Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly-Y M, et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science. 2013;341:569–73.
Neish AS. Microbes in gastrointestinal health and disease. Gastroenterology. 2009;136:65–80.
Stavrou G, Kotzampassi K. Gut microbiome, surgical complications and probiotics. Ann Gastroenterol. 2017;30:45–53.
Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, et al. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature. 2019;569:655–62.
Comments (0)