Early-onset hepatic veno-occlusive disease after liver transplantation: an institutional experience and analysis of a literature-based cohort

Dignan FL, Wynn RF, Hadzic N, Karani J, Quaglia A, Pagliuca A, et al. BCSH/BSBMT guideline: diagnosis and management of veno-occlusive disease (sinusoidal obstruction syndrome) following haematopoietic stem cell transplantation. Br J Haematol. 2013;163:444–57.

Article  CAS  PubMed  Google Scholar 

Wadleigh M, Ho V, Momtaz P, Richardson P. Hepatic veno-occlusive disease: pathogenesis, diagnosis and treatment. Curr Opin Hematol. 2003;10:451–62.

Article  PubMed  Google Scholar 

McKoy JM, Angelotta C, Bennett CL, Tallman MS, Wadleigh M, Evens AM, et al. Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): an overview from the research on adverse drug events and reports (RADAR) project. Leuk Res. 2007;31:599–604.

Article  CAS  PubMed  Google Scholar 

Brown AC. Liver toxicity related to herbs and dietary supplements: online table of case reports. Part 2 of 5 series. Food Chem Toxicol. 2017;107:472–501.

Article  CAS  PubMed  Google Scholar 

Lin G, Wang JY, Li N, Li M, Gao H, Ji Y, et al. Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum. J Hepatol. 2011;54:666–73.

Article  PubMed  Google Scholar 

Sterneck M, Wiesner R, Ascher N, Roberts J, Ferrell L, Ludwig J, et al. Azathioprine hepatotoxicity after liver transplantation. Hepatology. 1991;14:806–10.

Article  CAS  PubMed  Google Scholar 

Gane E, Langley P, Williams R. Massive ascitic fluid loss and coagulation disturbances after liver transplantation. Gastroenterology. 1995;109:1631–8.

Article  CAS  PubMed  Google Scholar 

Mor E, Pappo O, Bar-Nathan N, Shaharabani E, Shapira Z, Tur-Kaspa R, et al. Defibrotide for the treatment of veno-occlusive disease after liver transplantation. Transplantation. 2001;72:1237–40.

Article  CAS  PubMed  Google Scholar 

Nakazawa Y, Chisuwa H, Mita A, Ikegami T, Hashikura Y, Terada M, et al. Life-threatening veno-occlusive disease after living-related liver transplantation. Transplantation. 2003;75:727–30.

Article  PubMed  Google Scholar 

Takamura H, Nakanuma S, Hayashi H, Tajima H, Kakinoki K, Kitahara M, et al. Severe veno-occlusive disease/sinusoidal obstruction syndrome after deceased-donor and living-donor liver transplantation. Transplant Proc. 2014;46:3523–35.

Article  CAS  PubMed  Google Scholar 

Membreno FE, Ortiz J, Foster PF, Wright F, Ostrower VS, Metter JD, et al. Liver transplantation for sinusoidal obstructive syndrome (veno-occlusive disease): case report with review of the literature and the UNOS database. Clin Transplant. 2008;22:397–404.

Article  PubMed  Google Scholar 

Sebagh M, Azoulay D, Roche B, Hoti E, Karam V, Teicher E, et al. Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation. Liver Transpl. 2011;17:798–808.

Article  PubMed  Google Scholar 

Sanei MH, Schiano TD, Sempoux C, Fan C, Fiel MI. Acute cellular rejection resulting in sinusoidal obstruction syndrome and ascites postliver transplantation. Transplantation. 2011;92:1152–8.

Article  PubMed  Google Scholar 

Wang SE, Shyr YM, Lee RC. Hepatic veno-occlusive disease related to tacrolimus after pancreas transplantation. J Chin Med Assoc. 2013;76:358–60.

Article  PubMed  Google Scholar 

Kishida N, Shinoda M, Itano O, Obara H, Kitago M, Hibi T, et al. Increased incidence of thrombotic microangiopathy after ABO-incompatible living donor liver transplantation. Ann Transplant. 2016;21:755–64.

Article  CAS  PubMed  Google Scholar 

Mohty M, Malard F, Abecassis M, Aerts E, Alaskar AS, Aljurf M, et al. Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation. Bone Marrow Transplant. 2016;51:906–12.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marubbio AT, Danielson B. Hepatic veno-occlusive disease in a renal transplant patient receiving azathioprine. Gastroenterology. 1975;69:739–43.

Article  CAS  PubMed  Google Scholar 

Walter RB, Lukaschek J, Renner EL, Mullhaupt B, Bachli EB. Fatal hepatic veno-occlusive disease associated with terbinafine in a liver transplant recipient. J Hepatol. 2003;38:373–4.

Article  PubMed  Google Scholar 

Izaki T, Inomata Y, Asonuma K, Okajima H, Ohshiro H, Ueno M, et al. Early graft failure due to a veno-occlusive disease after a pediatric living donor liver transplantation. Pediatr Transplant. 2004;8:301–4.

Article  PubMed  Google Scholar 

Senzolo M, Patch D, Cholongitas E, Triantos C, Marelli L, Stigliano R, et al. Severe venoocclusive disease after liver transplantation treated with transjugular intrahepatic portosystemic shunt. Transplantation. 2006;82:132–5.

Article  PubMed  Google Scholar 

Kitajima K, Vaillant JC, Charlotte F, Eyraud D, Hannoun L. Intractable ascites without mechanical vascular obstruction after orthotopic liver transplantation: etiology and clinical outcome of sinusoidal obstruction syndrome. Clin Transplant. 2010;24:139–48.

Article  PubMed  Google Scholar 

Yamada N, Urahashi T, Ihara Y, Sanada Y, Wakiya T, Okada N, et al. Veno-occlusive disease/sinusoidal obstruction syndrome associated with potential antibody-mediated rejection after pediatric living donor liver transplantation: a case report. Transpl Proc. 2012;44:810–3.

Article  CAS  Google Scholar 

Campos-Varela I, Castells L, Dopazo C, Perez-Lafuente M, Allende H, Len O, et al. Transjugular intrahepatic portosystemic shunt for the treatment of sinusoidal obstruction syndrome in a liver transplant recipient and review of the literature. Liver Transpl. 2012;18:201–5.

Article  PubMed  Google Scholar 

Chen H, Wang X, Fan T, Li J, Wang L, Shen Z. A case of veno-occlusive disease following liver transplantation. Exp Ther Med. 2014;7:141–4.

Article  CAS  PubMed  Google Scholar 

Shen T, Feng XW, Geng L, Zheng SS. Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. World J Gastroenterol: WJG. 2015;21:6422–6.

Article  PubMed  PubMed Central  Google Scholar 

Nakanuma S, Miyashita T, Hayashi H, Tajima H, Takamura H, Tsukada T, et al. Extravasated platelet aggregation in liver zone 3 may correlate with the progression of sinusoidal obstruction syndrome following living donor liver transplantation: a case report. Exp Ther Med. 2015;9:1119–24.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shen T, Tang X, Xiang H, Zheng S. Graft failure from hepatic veno-occlusive disease after a liver transplant: a case report. Exp Clin Transplant. 2016;14:575–9.

PubMed  Google Scholar 

Marin-Gomez LM, Alamo-Martinez JM, Suarez-Artacho G, Ramirez-Santos J, Bernal-Bellido C, Barrera-Pulido L, et al. Is the sinusoidal obstructive syndrome post-liver transplantation a pathologic entity with a multifactorial etiology? Rev Esp Enferm Dig. 2015;107:235–8.

PubMed  Google Scholar 

Hou Y, Tam NL, Xue Z, Zhang X, Liao B, Yang J, et al. Management of hepatic vein occlusive disease after liver transplantation: a case report with literature review. Medicine (Baltimore). 2018;97: e11076.

Article  PubMed  Google Scholar 

Poli E, Kounis I, Guettier C, Verstuyft C, Coilly A, Sobesky R, et al. Post-liver transplantation sinusoidal obstruction syndrome with refractory ascites induced by mycophenolate mofetil. Hepatology. 2020;71:1508–10.

Article  PubMed  Google Scholar 

Liu Y, Sun LY, Zhu ZJ, Wei L, Qu W, Zeng ZG. Is sinusoidal obstructive syndrome a recurrent disease after liver transplantation? A case report. World J Clin Cases. 2021;9:489–95.

Article  PubMed  PubMed Central  Google Scholar 

Baliellas C, Llado L, Serrano T, Gonzalez-Vilatarsana E, Cachero A, Lopez-Dominguez J, et al. Sinusoidal obstruction syndrome as a manifestation of acute antibody-mediated rejection after liver transplantation. Am J Transplant. 2021;21:3775–9.

Article  PubMed  Google Scholar 

Lee TB, Yang K, Ko HJ, Shim JR, Choi BH, Lee JH, et al. Successful defibrotide treatment of a patient with veno-occlusive disease after living-donor liver transplantation: a case report. Medicine (Baltimore). 2021;100: e26463.

Article  CAS  PubMed  Google Scholar 

Zhou SN, Feng DN, Zhang N, Sun YL, Li YW, Zhou X, et al. Hepatic sinusoidal obstruction syndrome due to tacrolimus in a liver-transplantation recipient. Gastroenterol Rep (Oxf). 2021;9:485–7.

Article  PubMed  Google Scholar 

Bras G, Jelliffe DB, Stuart KL. Veno-occlusive disease of liver with nonportal type of cirrhosis, occurring in Jamaica. AMA Arch Pathol. 1954;57:285–300.

CAS  PubMed  Google Scholar 

Dhillon AP, Burroughs AK, Hudson M, Shah N, Rolles K, Scheuer PJ. Hepatic venular stenosis after orthotopic liver transplantation. Hepatology. 1994;19:106–11.

Article  CAS  PubMed  Google Scholar 

Caballero-Marcos A, Peligros I, Perez-Rojas J, Campos-Varela I, Colmenero J, Gomez-Bravo MA, et al. Sinusoidal obstruction syndrome after liver transplantation: a multicenter observational study. Liver Transpl. 2022;28:1257.

Article  PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif