Cavalcante GC, Marinho ANR, Anaissi AK, Vinasco-Sandoval T, Ribeiro-dos-Santos A, Vidal AF, et al. Whole mitochondrial genome sequencing highlights mitochondrial impact in gastric cancer. Sci Rep. 2019;9:15716.
Article PubMed PubMed Central Google Scholar
Andrieux P, Chevillard C, Cunha-Neto E, Nunes JPS. Mitochondria as a cellular hub in infection and inflammation. IJMS. 2021;22:11338.
Article CAS PubMed PubMed Central Google Scholar
Yan C, Duanmu X, Zeng L, Liu B, Song Z. Mitochondrial DNA: distribution, mutations, and elimination. Cells. 2019;8:379.
Article CAS PubMed PubMed Central Google Scholar
Chapman J, Ng YS, Nicholls TJ. The maintenance of mitochondrial DNA integrity and dynamics by mitochondrial membranes. Life. 2020;10:164.
Article CAS PubMed PubMed Central Google Scholar
Roger AJ, Muñoz-Gómez SA, Kamikawa R. The origin and diversification of mitochondria. Curr Biol. 2017;27:R1177–92.
Article CAS PubMed Google Scholar
Nguyen NNY, Kim SS, Jo YH. Deregulated mitochondrial DNA in diseases. DNA Cell Biol. 2020;39:1385–400.
Article CAS PubMed Google Scholar
Nissanka N, Moraes CT. Mitochondrial DNA heteroplasmy in disease and targeted nuclease-based therapeutic approaches. EMBO Rep. 2020;21:e49612.
Article CAS PubMed PubMed Central Google Scholar
Pérez-Amado CJ, Bazan-Cordoba A, Hidalgo-Miranda A, Jiménez-Morales S. Mitochondrial heteroplasmy shifting as a potential biomarker of cancer progression. IJMS. 2021;22:7369.
Article PubMed PubMed Central Google Scholar
van den Ameele J, Li AYZ, Ma H, Chinnery PF. Mitochondrial heteroplasmy beyond the oocyte bottleneck. Semin Cell Dev Biol. 2020;97:156–66.
Wang Y, McLean AS. The role of mitochondria in the immune response in critical illness. Crit Care. 2022;26:80.
Article CAS PubMed PubMed Central Google Scholar
Patrick KL, Watson RO. Mitochondria: powering the innate immune response to mycobacterium tuberculosis infection. Infect Immun. 2021;89:e00687-20.
Article PubMed PubMed Central Google Scholar
Chen M, Zhu X, Ran L, Lang H, Yi L, Mi M. Trimethylamine-N-Oxide induces vascular inflammation by activating the NLRP3 inflammasome through the SIRT3-SOD2-mtROS signaling pathway. JAHA. 2017;6:e006347.
Article PubMed PubMed Central Google Scholar
Swanson KV, Deng M, Ting JPY. The NLRP3 inflammasome: molecular activation and regulation to therapeutics. Nat Rev Immunol. 2019;19:477–89.
Article CAS PubMed PubMed Central Google Scholar
Stefano GB, Kream RM. Mitochondrial DNA heteroplasmy in human health and disease. Biomed Rep. 2016;4:259–62.
Article CAS PubMed PubMed Central Google Scholar
Wilton PR, Zaidi A, Makova K, Nielsen R. A population phylogenetic view of mitochondrial heteroplasmy. Genetics. 2018;208:1261–74.
Article PubMed PubMed Central Google Scholar
Prates Mori M, de Souza-Pinto NC. Role of mitochondrial dysfunction in the pathophysiology of DNA repair disorders: mitochondrial role in DNA repair disorders. Cell Biol Int. 2018;42:643–50.
Article CAS PubMed Google Scholar
Roca-Bayerri C, Robertson F, Pyle A, Hudson G, Payne BAI. Mitochondrial DNA damage and brain aging in human immunodeficiency virus. Clin Infect Dis. 2021;73:e466–73.
Article CAS PubMed Google Scholar
Han XY, Seo Y-H, Sizer KC, Schoberle T, May GS, Spencer JS, et al. A new Mycobacterium species causing diffuse lepromatous leprosy. Am J Clin Pathol. 2008;130:856–64.
Article CAS PubMed Google Scholar
Eichelmann K, González González SE, Salas-Alanis JC, Ocampo-Candiani J. Leprosy. An update: Definition, pathogenesis, classification, diagnosis, and treatment. Actas Dermo-Sifiliográficas. 2013;104:554–63.
Article CAS PubMed Google Scholar
Misch EA, Berrington WR, Vary JC, Hawn TR. Leprosy and the human genome. Microbiol Mol Biol Rev. 2010;74:589–620.
Article CAS PubMed PubMed Central Google Scholar
Cáceres-Durán MÁ. Epidemiological behavior of leprosy in several Latin American countries, 2011–2020 Comportamento epidemiológico da hanseníase em vários países da América Latina, 2011–2020. Rev Panam Salud Publica. 2022;46:e14.
Weekly Epidemiological Record, 2021, vol. 96, 36 [full issue] [Internet]. World Health Organization = Organisation mondiale de la Santé; 2021; p. 421–44. https://apps.who.int/iris/handle/10665/345048
Ridley DS, Jopling WH. Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis. 1966;34:255–73.
Cole ST, Eiglmeier K, Parkhill J, James KD, Thomson NR, Wheeler PR, et al. Massive gene decay in the leprosy bacillus. Nature. 2001;409:1007–11.
Article CAS PubMed Google Scholar
Oliveira MF, Medeiros RCA, Mietto BS, Calvo TL, Mendonça APM, Rosa TLSA, et al. Reduction of host cell mitochondrial activity as Mycobacterium leprae’s strategy to evade host innate immunity. Immunol Rev. 2021;301:193–208.
Article CAS PubMed PubMed Central Google Scholar
de Souza FG, Cavalcante GC. Mitochondria in Mycobacterium infection: From the immune system to mitochondrial haplogroups. IJMS. 2022;23:9511.
Article CAS PubMed PubMed Central Google Scholar
Wang D, Su L-Y, Zhang A-M, Li Y-Y, Li X-A, Chen L-L, et al. Mitochondrial DNA copy number, but not haplogroup, confers a genetic susceptibility to Leprosy in Han Chinese from Southwest China. PLOS ONE. 2012;7:e38848.
Article CAS PubMed PubMed Central Google Scholar
Pinto P, da Silva MB, Moreira FC, Bouth RC, Gobbo AR, Sandoval TV, et al. Leprosy piRnome: exploring new possibilities for an old disease. Sci Rep. 2020;10:12648.
Article CAS PubMed PubMed Central Google Scholar
Gobbo AR, Bouth RC, Moraes TMP, Pinto P, da Costa PF, Barreto JG, et al. NDO-BSA, LID-1, and NDO-LID antibody responses for infection and RLEP by quantitative PCR as a confirmatory test for early Leprosy diagnosis. Front Trop Dis. 2022;3:850886.
Villarroel MF, Orsini MBP, Lima RC, Antunes CMF. Comparative study of the cutaneous sensation of leprosy-suspected lesions using Semmes–Weinstein monofilaments and quantitative thermal testing. Lepr Rev. 2007;78:102–9.
Sambrook J. Molecular cloning: a laboratory manual (2nd edn). (No Title). 1989
Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30:2114–20.
Article CAS PubMed PubMed Central Google Scholar
Li H, Durbin R. Fast and accurate long-read alignment with Burrows–Wheeler transform. Bioinformatics. 2010;26:589–95.
Article PubMed PubMed Central Google Scholar
Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, et al. The sequence alignment/map format and SAMtools. Bioinformatics. 2009;25:2078–9.
Article PubMed PubMed Central Google Scholar
Weissensteiner H, Pacher D, Kloss-Brandstätter A, Forer L, Specht G, Bandelt H-J, et al. HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing. Nucleic Acids Res. 2016;44:W58-63.
Article CAS PubMed PubMed Central Google Scholar
Sherry ST, Ward M, Sirotkin K. dbSNP-database for single nucleotide polymorphisms and other classes of minor genetic variation. Genome Res. 1999;9:677–9.
Article CAS PubMed Google Scholar
Landrum MJ, Lee JM, Benson M, Brown GR, Chao C, Chitipiralla S, et al. ClinVar: improving access to variant interpretations and supporting evidence. Nucleic Acids Res. 2018;46:D1062–7.
Article CAS PubMed Google Scholar
Karczewski KJ, Francioli LC, Tiao G, Cummings BB, Alföldi J, Wang Q, et al. The mutational constraint spectrum quantified from variation in 141,456 humans. Nature. 2020;581:434–43.
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