Barbara G, Feinle-Bisset C, Ghoshal UC et al. the intestinal microenvironment and functional gastrointestinal disorders. Gastroenterology 2016;150:1305–1318.

Article  Google Scholar 

Shin A, Preidis GA, Shulman R et al. The gut microbiome in adult and pediatric functional gastrointestinal disorders. Clin Gastroenterol Hepatol 2019;17:256–274.

Article  CAS  PubMed  Google Scholar 

De Palma G, Shimbori C, Reed DE et al. Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice. Sci Transl Med 2022;14:eabj1895.

Article  PubMed  Google Scholar 

Bhattarai Y, Muniz Pedrogo DA, Kashyap PC. Irritable bowel syndrome: a gut microbiota-related disorder? Am J Physiol Gastrointest Liver Physiol 2017;312:G52–G62.

Article  PubMed  Google Scholar 

Pimentel M, Lembo A, Chey WD et al. Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med 2011;364:22–32.

Article  CAS  PubMed  Google Scholar 

Rezaie A, Heimanson Z, McCallum R et al. Lactulose breath testing as a predictor of response to rifaximin in patients with irritable bowel syndrome with diarrhea. Am J Gastroenterol 2019;114:1886–1893.

Article  PubMed  PubMed Central  Google Scholar 

Pimentel M, Chatterjee S, Chow EJ et al. Neomycin improves constipation-predominant irritable bowel syndrome in a fashion that is dependent on the presence of methane gas: subanalysis of a double-blind randomized controlled study. Dig Dis Sci 2006;51:1297–1301.

Article  CAS  PubMed  Google Scholar 

Lesmana E, Grover M. Editorial: faecal microbiota transplantation in IBS-moving closer or away from success? Aliment Pharmacol Ther 2023;58:950–951.

Article  PubMed  Google Scholar 

Villanueva-Millan MJ, Leite G, Wang J et al. Methanogens and hydrogen sulfide producing bacteria guide distinct gut microbe profiles and irritable bowel syndrome subtypes. Am J Gastroenterol 2022;117:2055–2066.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Villanueva-Millan MJ, Leite G, Morales W et al. Hydrogen sulfide producers drive a diarrhea-like phenotype and a methane producer drives a constipation-like phenotype in animal models. Dig Dis Sci. (Epub ahead of print). https://doi.org/10.1007/s10620-023-08197-5