Among 4803 patients, 2941 underwent PCI (805 females [27%]; 2136 males [73%]) and 1862 underwent CABG (391 females [21%] and 1471 males [79%]). Regardless of type of revascularization females were older, had higher body mass index and comorbidity burden. Females versus males had higher rates of death and death/MI (PCI: F 4.2, M 3.0; CABG: F 4.8, M: 3.7 deaths per 100 person-year and PCI: F 6.2, M 4.7; CABG: F 5.9, M: 4.7 deaths per 100 person-year, p<0.01). However, no sex-difference was observed in adjusted survival (PCI: HR 1.15, 95% CI 0.90-1.46; CABG: HR 1.26, 95% CI 0.93-1.70) or death/MI outcomes (PCI: HR 1.14, 95% CI 0.94-1.40; CABG: HR 1.23, 95% CI 0.94-1.61).

Our study revealed that females versus male had higher risk of death or death/MI. However, these differences in outcomes were explained by differences in demographic and clinical characteristics. Our results could be considered when contemplating revascularization strategy based on survival.