WHO. Ageing and health [Internet]. [cited 2022 Dec 2]. Available from: https://www.who.int/news-room/fact-sheets/detail/ageing-and-health.

Fantahun M, Berhane Y, Högberg U, Wall S, Byass P. Ageing of a rural Ethiopian population: who are the survivors? Public Health. 2009;123(4):326–30.

Article  CAS  PubMed  Google Scholar 

World Health Organization. UN Decade of Healthy Ageing [Internet]. 2020 [cited 2023 Jan 3]. Available from: https://www.who.int/initiatives/decade-of-healthy-ageing.

Safiliou-Rothschild C. Are older people responsible for high healthcare costs? In: CESifo Forum. München: ifo Institut für Wirtschaftsforschung an der Universität München; 2009. p. 57–64.

FDA. As You Age: You and Your Medicines [Internet]. 2019 [cited 2022 Dec 2]. Available from: https://www.fda.gov/drugs/information-consumers-and-patients-drugs/you-age-you-and-your-medicines.

Amarya S, Singh K, Sabharwal M. Ageing process and physiological changes. In: Gerontology. IntechOpen; 2018.

Shi S, Mörike K, Klotz U. The clinical implications of ageing for rational drug therapy. Eur J Clin Pharmacol. 2008;64(2):183–99.

Article  PubMed  Google Scholar 

Lavan AH, O’Grady J, Gallagher PF. Appropriate prescribing in the elderly: Current perspectives. World. 2015;2.

Panel 2019 American Geriatrics Society Beers Criteria® Update Expert, Fick DM, Semla TP, Steinman M, Beizer J, Brandt N, et al. American Geriatrics Society 2019 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2019;67(4):674–94.

Article  Google Scholar 

O’Mahony D, O’Sullivan D, Byrne S, O’Connor MN, Ryan C, Gallagher P. STOPP/START criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing. 2014;44(2):213–8.

Article  PubMed  PubMed Central  Google Scholar 

Renom-Guiteras A, Meyer G, Thürmann PA. The EU(7)-PIM list: a list of potentially inappropriate medications for older people consented by experts from seven European countries. Eur J Clin Pharmacol. 2015;71(7):861–75.

Article  PubMed  PubMed Central  Google Scholar 

Foubert K, Capiau A, Mehuys E, De Bolle L, Somers A, Petrovic M, et al. Ghent older people’s prescriptions community pharmacy screening (GheOP3S)-tool version 2: update of a tool to detect drug-related problems in older people in primary care. Drugs Aging. 2021;38(6):523–33.

Article  PubMed  PubMed Central  Google Scholar 

Holt S, Schmiedl S, Thürmann PA. Potentially inappropriate medications in the elderly. Dtsch Arztebl Int. 2010;107(31–32):543.

PubMed  PubMed Central  Google Scholar 

Gallagher P, Lang PO, Cherubini A, Topinková E, Cruz-Jentoft A, Montero Errasquín B, et al. Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals. Eur J Clin Pharmacol. 2011;67(11):1175–88.

Article  PubMed  Google Scholar 

Najjar M, Sulaiman S, Balubaid H, Sallout M, Alessa M. Potentially inappropriate medication-related adverse drug reaction among hospitalized geriatric patients: a combined interventional study. J Gerontol Geriatr Med. 2019;5:39.

Google Scholar 

Abdelwahed AA, El-Dahiyat F, Aljawamis D, Al Ajimi J, Bin Rafeea KJ. Potentially inappropriate medications in older adults according to Beers criteria 2019: prevalence and risk factors. Int J Clin Pract. 2021;75(11): e14715.

Article  PubMed  Google Scholar 

Awad A, Hanna O. Potentially inappropriate medication use among geriatric patients in primary care setting: a cross-sectional study using the Beers, STOPP, FORTA and MAI criteria. PLoS ONE. 2019;14(6): e0218174.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alshammari H, Al-Saeed E, Ahmed Z, Aslanpour Z. Prevalence and predictors of potentially inappropriate medications among patients aged≥ 65 years on hospital admissions in Kuwait. Clin Interv Aging. 2022;17:1025–36.

Article  PubMed  PubMed Central  Google Scholar 

Harugeri A, Joseph J, Parthasarathi G, Ramesh M, Guido S. Potentially inappropriate medication use in elderly patients: a study of prevalence and predictors in two teaching hospitals. J Postgrad Med. 2010;56(3):186.

Article  CAS  PubMed  Google Scholar 

Nagendra Vishwas H, Harugeri A, Parthasarathi G, Ramesh M. Potentially inappropriate medication use in Indian elderly: comparison of Beers’ criteria and Screening Tool of Older Persons’ potentially inappropriate Prescriptions. Geriatr Gerontol Int. 2012;12(3):506–14.

Article  Google Scholar 

Sharma R, Bansal P, Garg R, Ranjan R, Kumar R, Arora M. Prevalence of potentially inappropriate medication and its correlates in elderly hospitalized patients: a cross-sectional study based on Beers criteria. J Family Community Med. 2020;27(3):200.

Article  PubMed  PubMed Central  Google Scholar 

Tian F, Li H, Chen Z, Xu T. Potentially inappropriate medications in Chinese older outpatients in tertiary hospitals according to Beers criteria: a cross-sectional study. Int J Clin Pract. 2021;75(8): e14348.

Article  PubMed  Google Scholar 

Akande-Sholabi W, Adebusoye LA, Olowookere OO. Potentially inappropriate medication use among older patients attending a geriatric centre in south-west Nigeria. Pharm Pract. 2018;16(3):1235.

Google Scholar 

Mekonnen A, Bhagavathula AS. Inappropriate medication use in the elderly population attending gondar University hospital: a preliminary assessment. Int J Pharm Pharm Sci. 2014;6(10):540–3.

Google Scholar 

Sada O. Irrational use of medications among elderly patients in an Ethiopian referral hospital. Afr J Pharm Pharmacol. 2017;11(15):191–4.

Article  Google Scholar 

Teka F, Teklay G, Ayalew E, Kassa TT. Prevalence of potentially inappropriate medications in Ayder referral hospital, Tigray region, Northern Ethiopia: prospective study. J Drug Deliv Ther. 2016;6(6):16–21.

Google Scholar 

Abegaz TM, Birru EM, Mekonnen GB. Potentially inappropriate prescribing in Ethiopian geriatric patients hospitalized with cardiovascular disorders using START/STOPP criteria. PLoS ONE. 2018;13(5): e0195949.

Article  PubMed  PubMed Central  Google Scholar 

Tesfaye BT, Tessema MT, Yizengaw MA, Bosho DD. Potentially inappropriate medication use among older adult patients on follow-up at the chronic care clinic of a specialized teaching hospital in Ethiopia. A cross-sectional study. BMC Geriatr. 2021;21(1):1–11.

Article  Google Scholar 

Moriarty F, Bennett K, Fahey T, Kenny RA, Cahir C. Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people. Eur J Clin Pharmacol. 2015;71(4):473–82.

Article  PubMed  PubMed Central  Google Scholar 

DeRhodes KH. The dangers of ignoring the beers criteria—the prescribing cascade. JAMA Intern Med. 2019;179(7):863.

Article  PubMed  Google Scholar 

Muhlack DC, Hoppe LK, Weberpals J, Brenner H, Schöttker B. The association of potentially inappropriate medication at older age with cardiovascular events and overall mortality: a systematic review and meta-analysis of cohort studies. J Am Med Dir Assoc. 2017;18(3):211–20.

Article  PubMed  Google Scholar 

Cardwell K, Kerse N, Hughes CM, Teh R, Moyes SA, Menzies O, et al. Does potentially inappropriate prescribing predict an increased risk of admission to hospital and mortality? A longitudinal study of the ‘oldest old.’ BMC Geriatr. 2020;20(1):1–9.

Article  Google Scholar 

Page RL II, Ruscin JM. The risk of adverse drug events and hospital-related morbidity and mortality among older adults with potentially inappropriate medication use. Am J Geriatr Pharmacother. 2006;4(4):297–305.

Article  PubMed  Google Scholar 

Galli TB, Reis WC, Andrzejevski VM. Potentially inappropriate prescribing and the risk of adverse drug reactions in critically ill older adults. Pharm Pract. 2016;14(4):818.

Google Scholar 

Onder G, Landi F, Liperoti R, Fialova D, Gambassi G, Bernabei R. Impact of inappropriate drug use among hospitalized older adults. Eur J Clin Pharmacol. 2005;61(5):453–9.

Article  PubMed  Google Scholar 

Laroche M, Charmes J, Nouaille Y, Picard N, Merle L. Is inappropriate medication use a major cause of adverse drug reactions in the elderly? Br J Clin Pharmacol. 2007;63(2):177–86.

Article  PubMed  Google Scholar 

Henschel F, Redaelli M, Siegel M, Stock S. Correlation of incident potentially inappropriate medication prescriptions and hospitalization: an analysis based on the PRISCUS list. Drugs-Real World Outcomes. 2015;2(3):249–59.

Article  PubMed  PubMed Central  Google Scholar 

Unutmaz GD, Soysal P, Tuven B, Isik AT. Costs of medication in older patients: before and after comprehensive geriatric assessment. Clin Interv Aging. 2018;13:607.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stockl KM, Le L, Zhang S, Harada AS. Clinical and economic outcomes associated with potentially inappropriate prescribing in the elderly. Am J Manag Care. 2010;16(1):e1-10.

PubMed  Google Scholar 

Fick D. Potentially inappropriate medication use in a Medicare managed care population: association with higher costs and utilization. J Manag Care Pharm. 2001;7(5):407–13.

Google Scholar 

Fu AZ, Jiang JZ, Reeves JH, Fincham JE, Liu GG, Perri M III. Potentially inappropriate medication use and healthcare expenditures in the US community-dwelling elderly. Med Care. 2007;45:472–6.

Article  PubMed  Google Scholar 

Fick DM, Mion LC, Beers MH, Waller JL. Health outcomes associated with potentially inappropriate medication use in older adults. Res Nurs Health. 2008;31(1):42–51.

Article  PubMed  PubMed Central  Google Scholar 

Heider D, Matschinger H, Meid AD, Quinzler R, Adler JB, Günster C, et al. Health service use, costs, and adverse events associated with potentially inappropriate medication in old age in Germany: retrospective matched cohort study. Drugs Aging. 2017;34(4):289–301.

Article  PubMed  Google Scholar 

Akazawa M, Imai H, Igarashi A, Tsutani K. Potentially inappropriate medication use in elderly Japanese patients. Am J Geriatr Pharmacother. 2010;8(2):146–60.

Article  PubMed  Google Scholar 

Dionne PA, Vasiliadis HM, Latimer E, Berbiche D, Preville M. Economic impact of inappropriate benzodiazepine prescribing and related drug interactions among elderly persons. Psychiatr Serv. 2013;64(4):331–8.

Article  PubMed  Google Scholar