In a previous study, we demonstrated an association between a low response to rubella vaccination and a decreased acquisition of anti-severe acute respiratory syndrome coronavirus 2 spike immunoglobulin G (anti-S IgG) shortly after the second dose of the BNT162b2 vaccine. The present study aimed to explore whether this association persists in terms of long-term antibody retention following the second dose of BNT162b2. Through multivariable analysis, we found a significant association between a low response to rubella vaccination and reduced anti-S IgG titers approximately eight months after the second dose of BNT162b2.

Antibody

BNT162b2

COVID-19

Rubella

SARS-CoV-2

Vaccine

© 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights reserved.