Formulation and evaluation of retinyl palmitate and vitamin E nanoemulsion for skin care

Article title

Abstract

Keywords

Introduction

Material and methods

Materials

Methods

Analytical methods

Solubility of retinyl palmitate and vitamin E

Formulation of the Nanoemulsion (NE)

Preparation of surfactant and co surfactant mixture (Smix)

Preparation of the nanoemulsion (NE)

Preparation of the final formulation

Characterization of the prepared NE

Measurement of droplet size and charge

Assay of RP and VE in the selected formulae (FF1 and FF2)

Rheological study

Diffusion study

Skin irritation/corrosive potential test

Preliminary stability study at room temperature

Statistical analysis

Results and discussion

Method of analysis of Retinyl palmitate (RP) and vitamin E (VE)

Solubility study of retinol palmitate (RP) and vitamin E (VE)

Formulation of the Nanoemulsion (NE)

Characterization of NE

Rheological study

Diffusion study

Irritation study

Preliminary stability test at room temperature

Conclusions

Author contributions

References

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