Article title

Abstract

Keywords

Introduction

SLNs versus NLCs

Types of SLNs and NLCs

Types of SLNs

Type I (Homogeneous matrix model)

Type II (Drug enriched shell model)

Type III (Drug enriched core model)

Types of NLCs

Imperfect type (Imperfectly structured solid matrix)

Amorphous type (Structureless solid amorphous matrix)

Multiple types (Multiple oils in fat in water)

Methods of preparation

High energy approaches

High-Pressure Homogenization (HPH) method

Hot High-Pressure Homogenization (HHPH) method

Cold High-Pressure Homogenization (CHPH) method

High Shear Homogenization (HSH) and/or ultrasonication (US) method

Low-energy approaches

Microemulsion (MM) technique

Membrane contactor (MC) technique

Phase inversion temperature (PIT) technique

Coacervation (CV) technique

Double emulsion (DE) technique

Microemulsion cooling (MEC) technique

Approaches with organic solvents

Emulsification solvent-evaporation (ESE) technique

Emulsification solvent-diffusion (ESD) technique

Solvent injection (SI) technique

Supercritical fluid (SCF) technique

Particle from Gas Saturated Solution (PGSS) method and Gas Assisted Melting Atomization (GAMA) method

Drug release

Conclusion

Conflict of interest

Acknowledgements

References