LETTER TO EDITOR Year : 2022  |  Volume : 11  |  Issue : 4  |  Page : 258

Salivary proteome profile during the fertile phase of menstrual cycle: Correspondence

Pathum Sookaromdee1, Viroj Wiwanitkit2
1 Private Academic Consultant, Bangkok, Thailand
2 Department of Community Medicine, Dr. D. Y Patil University, Pune, Maharashtra, India

Date of Submission30-Nov-2021Date of Acceptance16-Aug-2022Date of Web Publication07-Oct-2022

Correspondence Address:
Dr. Pathum Sookaromdee
Private Academic Consultant, 111 Bangkok 122 Bangkok 103300
Thailand

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/gmit.gmit_130_21

How to cite this article:
Sookaromdee P, Wiwanitkit V. Salivary proteome profile during the fertile phase of menstrual cycle: Correspondence. Gynecol Minim Invasive Ther 2022;11:258
How to cite this URL:
Sookaromdee P, Wiwanitkit V. Salivary proteome profile during the fertile phase of menstrual cycle: Correspondence. Gynecol Minim Invasive Ther [serial online] 2022 [cited 2022 Nov 8];11:258. Available from: https://www.e-gmit.com/text.asp?2022/11/4/258/358043

Dear Editor,

We would like to share ideas on “Salivary proteome profile of women during the fertile phase of menstrual cycle as characterized by mass spectrometry.”[1] Saibaba et al. concluded that “Total salivary proteome profile has been listed …. validation is required before arriving to a candidate bio-marker protein.”[1] We agree that there is potential that salivary proteome might be a useful biomarker. In laboratory medicine, there are many considerations on accuracy and interference of salivary proteome biomarker. Contamination is easy and specimen collection needs a good procedure. In the present report, tooth brushing is used for preparation. However, other sources of interferences such as food and drink as well as quality of tooth brushing and toothpaste should be discussed. Furthermore, underlying physiological condition of the subjects might interfere salivary proteome profile. Nutritional status of subjects might also affect the profile.[2] Further studies to assess those confounding factors are interesting.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 

  References 
1.Saibaba G, Rajesh D, Muthukumar S, Sathiyanarayanan G, Aarthy AP, Archunan G. Salivary proteome profile of women during fertile phase of menstrual cycle as characterized by mass spectrometry. Gynecol Minim Invasive Ther 2021;10:226-34.  
  [Full text]  2.Fonteles CS, Dos Santos CF, da Silva Alves KS, de Miranda Mota AC, Damasceno JX, Fonteles MC. Comparative proteomic analysis of human whole saliva of children with protein-energy undernutrition. Nutrition 2012;28:744-8.