From Coronaries to Cirrhosis: The Role of Percutaneous Coronary Intervention and Dual Antiplatelet Therapy in End-Stage Liver Disease

1. Torrado, J, Buckley, L, Durán, A, et al. Restenosis, stent thrombosis, and bleeding complications: navigating between scylla and charybdis. J Am Coll Cardiol. 2018;71:1676-1695. doi:10.1016/j.jacc.2018.02.023
Google Scholar | Crossref | Medline2. Levine, GN, Bates, ER, Bittl, JA, et al. 2016 ACC/AHA Guideline Focused Update on duration of dual antiplatelet therapy in patients with coronary artery disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention, 2011 ACCF/AHA guideline for coronary artery bypass graft surgery, 2012 ACC/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease, 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction, 2014 AHA/ACC guideline for the management of patients with non–ST-elevation acute coronary syndromes, and 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery. Circulation 2016;134:e123-e155. doi:10.1161/CIR.0000000000000404
Google Scholar | Crossref3. Yusuf, S, Zhao, F, Mehta, SR, Chrolavicius, S, Tognoni, G, Fox, KK; Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494-502. doi:10.1056/NEJMoa010746
Google Scholar | Crossref | Medline | ISI4. Navarese, EP, Kowalewski, M, Kandzari, D, et al. First-generation versus second-generation drug-eluting stents in current clinical practice: updated evidence from a comprehensive meta-analysis of randomised clinical trials comprising 31 379 patients. Open Heart. 2014;1:e000064. doi:10.1136/openhrt-2014-000064
Google Scholar | Crossref | Medline5. Tripodi, A. Hemostasis abnormalities in cirrhosis. Curr Opin Hematol. 2015;22:406-412. doi:10.1097/MOH.0000000000000164
Google Scholar | Crossref | Medline6. Flores, B, Trivedi, HD, Robson, SC, et al. Hemostasis, bleeding and thrombosis in liver disease. J Transl Sci. 2017;3:10. doi:10.15761/JTS.1000182
Google Scholar | Crossref7. Bellemain-Appaix, A, O’Connor, SA, Silvain, J, et al; ACTION Group . Association of clopidogrel pretreatment with mortality, cardiovascular events, and major bleeding among patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis. JAMA. 2012;308:2507-2516. doi:10.1001/jama.2012.50788
Google Scholar | Crossref | Medline | ISI8. Esmonde, S, Sharma, D, Peace, A. Antiplatelet agents in uncertain clinical scenarios—a bleeding nightmare. Cardiovasc Diagn Ther. 2018;8:647-662. doi:10.21037/cdt.2018.06.09
Google Scholar | Crossref | Medline9. Lu, DY, Saybolt, MD, Kiss, DH, et al. One-year outcomes of percutaneous coronary intervention in patients with end-stage liver disease. Clin Med Insights Cardiol. 2020;14:1179546820901491. doi:10.1177/1179546820901491
Google Scholar | SAGE Journals10. Azarbal, B, Poommipanit, P, Arbit, B, et al. Feasibility and safety of percutaneous coronary intervention in patients with end-stage liver disease referred for liver transplantation. Liver Transpl. 2011;17:809-813. doi:10.1002/lt.22301
Google Scholar | Crossref | Medline | ISI11. Russo, MW, Pierson, J, Narang, T, Montegudo, A, Eskind, L, Gulati, S. Coronary artery stents and antiplatelet therapy in patients with cirrhosis. J Clin Gastroenterol. 2012;46:339-344. doi:10.1097/MCG.0b013e3182371258
Google Scholar | Crossref | Medline12. Singh, V, Patel, NJ, Rodriguez, AP, et al. Percutaneous coronary intervention in patients with end-stage liver disease. Am J Cardiol. 2016;117:1729-1734. doi:10.1016/j.amjcard.2016.03.010
Google Scholar | Crossref | Medline13. Krill, T, Brown, G, Weideman, RA, et al. Patients with cirrhosis who have coronary artery disease treated with cardiac stents have high rates of gastrointestinal bleeding, but no increased mortality. Aliment Pharmacol Ther. 2017;46:183-192. doi:10.1111/apt.14121
Google Scholar | Crossref | Medline14. Howard, CE, Nambi, V, Jneid, H, et al. Extended duration of dual-antiplatelet therapy after percutaneous coronary intervention: how long is too long? J Am Heart Assoc. 2019;8:e012639. doi:10.1161/JAHA.119.012639
Google Scholar | Crossref15. Wu, VCC, Chen, SW, Chou, AH, et al. Dual antiplatelet therapy in patients with cirrhosis and acute myocardial infarction—a 13-year nationwide cohort study. PLoS One. 2019;14:e0223380. doi:10.1371/journal.pone.0223380
Google Scholar | Crossref16. Sasso, R, Rockey, DC. Anticoagulation therapy in patients with liver cirrhosis is associated with an increased risk of variceal hemorrhage. Am J Med. 2019;132:758-766. doi:10.1016/j.amjmed.2019.01.006
Google Scholar | Crossref | Medline17. Urban, P, Meredith, IT, Abizaid, A, et al; LEADERS FREE Investigators . Polymer-free drug-coated coronary stents in patients at high bleeding risk. N Engl J Med. 2015;373:2038-2047. doi:10.1056/NEJMoa1503943
Google Scholar | Crossref | Medline | ISI18. Valgimigli, M, Patialiakas, A, Thury, A, et al; ZEUS Investigators . Zotarolimus-eluting versus bare-metal stents in uncertain drug-eluting stent candidates. J Am Coll Cardiol. 2015;65:805-815. doi:10.1016/j.jacc.2014.11.053
Google Scholar | Crossref | Medline19. Varenne, O, Cook, S, Sideris, G, et al; SENIOR Investigators . Drug-eluting stents in elderly patients with coronary artery disease (SENIOR): a randomised single-blind trial. Lancet. 2018;391:41-50. doi:10.1016/S0140-6736(17)32713-7
Google Scholar | Crossref | Medline20. Mehran, R, Baber, U, Sharma, SK, et al. Ticagrelor with or without aspirin in high-risk patients after PCI. N Engl J Med. 2019;381:2032-2042. doi:10.1056/NEJMoa1908419
Google Scholar | Crossref | Medline21. Watanabe, H, Domei, T, Morimoto, T, et al. Effect of 1-month dual antiplatelet therapy followed by clopidogrel vs 12-month dual antiplatelet therapy on cardiovascular and bleeding events in patients receiving PCI: the STOPDAPT-2 randomized clinical trial. JAMA. 2019;321:2414-2427. doi:10.1001/jama.2019.8145
Google Scholar | Crossref | Medline

Comments (0)

No login
gif