Harmony in nature's elixir: a comprehensive exploration of ethanol and nano-formulated extracts from Passiflora incarnata leaves: unveiling in vitro cytotoxicity, acute and sub-acute toxicity profiles in Swiss albino mice

Agbor G, Tarkang P, Fogha J, Biyiti L, Tamze V, Messi H et al (2012) Acute and subacute toxicity studies of aqueous extract of Morinda lucida stem bark. J Pharmacol Toxicol 7(3):158–165

Article  Google Scholar 

Agraharam G, Girigoswami A, Girigoswami K (2021) Nanoencapsulated myricetin to improve antioxidant activity and bioavailability: a study on zebrafish embryos. Chemistry 4(1):1–17. https://doi.org/10.3390/chemistry4010001

Article  CAS  Google Scholar 

Akshaya K, Arthi C, Pavithra A, Poovizhi P, Antinate SS, Hikku G et al (2020) Bioconjugated gold nanoparticles as an efficient colorimetric sensor for cancer diagnostics. Photodiagn Photodyn Ther 30:101699. https://doi.org/10.1016/j.pdpdt.2020.101699

Article  CAS  Google Scholar 

Alelign T, Chalchisa D, Fekadu N, Solomon D, Sisay T, Debella A, Petros B (2020) Evaluation of acute and sub-acute toxicity of selected traditional antiurolithiatic medicinal plant extracts in Wistar albino rats. Toxicol Rep 7:1356–1365

Article  CAS  PubMed  PubMed Central  Google Scholar 

Allkin B (2017) Useful plants—medicines: at least 28,187 plant species are currently recorded as being of medicinal use. Royal Botanic Gardens, Kew, London

Google Scholar 

Balasubramanian D, Girigoswami A, Girigoswami K (2023) Nano resveratrol and its anticancer activity. Curr Appl Sci Technol. https://doi.org/10.55003/cast.2022.03.23.010

Article  Google Scholar 

Biswas K, Janani G, Udayakumar S, Deepika B, Girigoswami K (2023) Rough edges of reduced graphene oxide (rGO) sheets elicit anticancerous activities: an in vitro study. Results Chem 6:101207

Article  CAS  Google Scholar 

Chatterjee S, Harini K, Girigoswami A, Nag M, Lahiri D, Girigoswami K (2023) Nanodecoys: a quintessential candidate to augment theranostic applications for a plethora of diseases. Pharmaceutics 15(1):73. https://doi.org/10.3390/pharmaceutics15010073

Article  CAS  Google Scholar 

Dantas L-P, de Oliveira-Ribeiro A, de Almeida-Souza L-M, Groppo F-C (2017) Effects of Passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction. Med Oral Patol Oral Cir Bucal 22(1):e95

PubMed  Google Scholar 

Deepika B, Gopikrishna A, Girigoswami A, Banu MN, Girigoswami K (2022) Applications of nanoscaffolds in tissue engineering. Curr Pharmacol Rep 8(3):171–187. https://doi.org/10.1007/s40495-022-00284-x

Article  Google Scholar 

Dhawan K, Kumar S, Sharma A (2001a) Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. J Ethnopharmacol 78(2–3):165–170

Article  CAS  PubMed  Google Scholar 

Dhawan K, Kumar S, Sharma A (2001b) Anxiolytic activity of aerial and underground parts of Passiflora incarnata. Fitoterapia 72(8):922–926

Article  CAS  PubMed  Google Scholar 

Erben U, Loddenkemper C, Doerfel K, Spieckermann S, Haller D, Heimesaat MM et al (2014) A guide to histomorphological evaluation of intestinal inflammation in mouse models. Int J Clin Exp Pathol 7(8):4557

PubMed  PubMed Central  Google Scholar 

Esra A, Cakici O (2023) Evaluation of the histopathological changes accompanied for the toxic effects of diazinon on the spleen of mice. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi 26(5):1099–1107

Article  Google Scholar 

Garg P, Garg R (2018) Qualitative and quantitative analysis of leaves and stem of Tinospora cordifolia in different solvent extract. J Drug Deliv Ther 8(5-s):259–264

Article  Google Scholar 

Girigoswami K, Girigoswami A, Deepika B, Gopikrishna A (2023) Method for the preparation of nanoformulation of Passiflora Incarnata leaf extract and its applications thereof. Indian Patent No. 437722. Granted on 07.07.2023

Gowtham P, Girigoswami K, Pallavi P, Harini K, Gurubharath I, Girigoswami A (2022) Alginate-derivative encapsulated carbon coated manganese-ferrite nanodots for multimodal medical imaging. Pharmaceutics 14(12):2550. https://doi.org/10.3390/pharmaceutics14122550

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guerra Ruiz AR, Crespo J, López Martínez RM, Iruzubieta P, Casals Mercadal G, Lalana Garcés M et al (2021) Measurement and clinical usefulness of bilirubin in liver disease. Adv Lab Med/avances En Medicina De Laboratorio 2(3):352–361

Article  PubMed  Google Scholar 

Guerrero FA, Medina GM (2017) Effect of a medicinal plant (Passiflora incarnata L.) on sleep. Sleep Sci 10(03):96–100

Article  PubMed  PubMed Central  Google Scholar 

Hanif MO, Bali A, Ramphul K. (2023) Acute Renal Tubular Necrosis Jul 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29939592

Harini K, Alomar SY, Vajagathali M, Manoharadas S, Thirumalai A, Girigoswami K, Girigoswami A (2024) Niosomal bupropion: exploring therapeutic frontiers through behavioral profiling. Pharmaceuticals 17(3):366

Article  CAS  PubMed  PubMed Central  Google Scholar 

Janda K, Wojtkowska K, Jakubczyk K, Antoniewicz J, Skonieczna-Żydecka K (2020) Passiflora incarnata in neuropsychiatric disorders—a systematic review. Nutrients 12(12):3894

Article  PubMed  PubMed Central  Google Scholar 

Kengkoom K, Chaimongkolnukul K, Cherdyu S, Inpunkaew R, Ampawong S (2012) Acute and sub-chronic oral toxicity studies of the extracts from herbs in Phikud Navakot. Afr J Biotech 11(48):10903–10911

Article  Google Scholar 

Khan H, Nabavi SM (2019) Passiflora (Passiflora incarnata). In: Nonvitamin and nonmineral nutritional supplements. Elsevier, Amsterdam, pp 361–366

Google Scholar 

Khandker SS, Alam M, Uddin F, Shapla UM, Lubna N, Mazumder TA et al (2022) Subchronic toxicity study of Alternanthera philoxeroides in Swiss albino mice having antioxidant and anticoagulant activities. J Toxicol. https://doi.org/10.1155/2022/8152820

Article  PubMed  PubMed Central  Google Scholar 

Kifayatullah M, Mustafa MS, Sengupta P, Sarker MMR, Das A, Das SK (2015) Evaluation of the acute and sub-acute toxicity of the ethanolic extract of Pericampylus glaucus (Lam.) Merr. in BALB/c mice. J Acute Dis 4(4):309–315

Article  Google Scholar 

Kim M, Lim H-S, Lee H-H, Kim T-H (2017) Role identification of Passiflora incarnata Linnaeus: a mini review. J Menopausal Med 23(3):156–159

Article  PubMed  PubMed Central  Google Scholar 

Kumar V, Bansal V, Madhavan A, Kumar M, Sindhu R, Awasthi MK et al (2022) Active pharmaceutical ingredient (API) chemicals: a critical review of current biotechnological approaches. Bioengineered 13(2):4309–4327

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lawal B, Shittu OK, Oibiokpa FI, Mohammed H, Umar SI, Haruna GM (2016) Antimicrobial evaluation, acute and sub-acute toxicity studies of Allium sativum. J Acute Dis 5(4):296–301

Article  Google Scholar 

Le J, Ji H, Zhou X, Wei X, Chen Y, Fu Y et al (2021) Pharmacology, toxicology, and metabolism of sennoside A, A medicinal plant-derived natural compound. Front Pharmacol 12:714586

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ma W-D, Zou Y-P, Wang P, Yao X-H, Sun Y, Duan M-H et al (2014) Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway. Food Chem Toxicol 70:1–8

Article  CAS  PubMed  Google Scholar 

Minegishi S, Luft FC, Titze J, Kitada K (2020) Sodium handling and interaction in numerous organs. Am J Hypertens 33(8):687–694

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miroddi M, Calapai G, Navarra M, Minciullo P, Gangemi S (2013) Passiflora incarnata L.: ethnopharmacology, clinical application, safety and evaluation of clinical trials. J Ethnopharmacol 150(3):791–804

Article  CAS  PubMed  Google Scholar 

Mone A, Chang S, Poppers D (2016) Worsening hepatic function in paroxysmal nocturnal hemoglobinuria (PNH) leading to hemolysis, gallstones, and progressive hepatic fibrosis: 1812. Am J Gastroenterol 111:S868–S869

Article  Google Scholar 

Mudaraddi R, Kulkarni SP, Trivedi DJ, Patil VS, Kamble PS (2015) Association of serum electrolytes and urea levels with cardiac markers in acute myocardial infarction. Int J Clin Biochem Res 29:14–77

Google Scholar 

Mukherjee P, Roy S, Ghosh D, Nandi S (2022) Role of animal models in biomedical research: a review. Lab Anim Res 38(1):18

Article  CAS  PubMed  PubMed Central  Google Scholar 

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