Synthesis of chalcone derivatives (1–5)

The following is a general method for synthesizing pyrazoline derivatives (6–10)

The compound (1) is (E)-3-(4-methoxyphenyl)-1-(pyridine-2-yl) prop-2-en-1-one

The compound (2) is (E)-3-(4-nitrophenyl)-1-(pyridin-2-yl) prop-2-en-1-one

The compound (3) is (E)-3-(4-(dimethylamino) phenyl)-1-(pyridin-2-yl) prop-2-en-1-one

The compound (4) is (E)-3-(4-chlorophenyl)-1-(pyridin-2-yl) prop-2-en-1-one

The compound (5) is (E)-3-phenyl-1-(pyridine-2-yl) prop-2-en-1-one

The compound (6) is 4-(5-(4-methoxyphenyl)-3-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide

The compound (7) is 4-(5-(4-nitrophenyl)-3-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide

4-(5-(4-(dimethylamino) phenyl)-3-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide (8)

The compound (9) is 4-(5-(4-chlorophenyl)-3-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide

The compound (10) is 4-(5-phenyl-3-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide